Long-term health-related quality of life after trauma with and without traumatic brain injury: a prospective cohort study
| العنوان: | Long-term health-related quality of life after trauma with and without traumatic brain injury: a prospective cohort study |
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| المؤلفون: | Kiwanuka, Olivia, Lassarén, Philipp, Thelin, Eric P., Hånell, Anders, Sandblom, Gabriel, Fagerdahl, Ami, Boström, Lennart |
| المصدر: | Scientific Reports. 13(1) |
| الوصف: | To purpose was to assess and compare the health-related quality of life (HRQoL) and risk of depression two years after trauma, between patients with and without traumatic brain injury (TBI) in a mixed Swedish trauma cohort. In this prospective cohort study, TBI and non-TBI trauma patients included in the Swedish Trauma registry 2019 at a level II trauma center in Stockholm, Sweden, were contacted two years after admission. HRQoL was assessed with RAND-36 and EQ-5D-3L, and depression with Montgomery Åsberg depression Rating Scale self-report (MADRS-S). Abbreviated Injury Score (AIS) head was used to grade TBI severity, and American Society of Anesthesiologists (ASA) score was used to assess comorbidities. Data were compared using Chi-squared test, Mann Whitney U test and ordered logistic regression, and Bonferroni correction was applied. A total of 170 of 737 eligible patients were included. TBI was associated with higher scores in 5/8 domains of RAND-36 and 3/5 domains of EQ-5D (p < 0.05). No significant difference in MADRS-S. An AIS (head) of three or higher was associated with lower scores in five domains of RAND-36 and two domains of EQ-5D but not for MADRS-S. An ASA-score of three was associated with lower scores in all domains of both RAND-36 (p < 0.05, except mental health) and EQ-5D (p < 0.001, except anxiety/depression), but not for MADRS-S. In conclusion, patients without TBI reported a lower HRQoL than TBI patients two years after trauma. TBI severity assessed according to AIS (head) was associated with HRQoL, and ASA-score was found to be a predictor of HRQoL, emphasizing the importance of considering pre-injury health status when assessing outcomes in TBI patients. |
| وصف الملف: | electronic |
| الوصول الحر: | https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-500323Test https://doi.org/10.1038/s41598-023-30082-4Test https://uu.diva-portal.org/smash/get/diva2:1750959/FULLTEXT01.pdfTest |
| قاعدة البيانات: | SwePub |
| تدمد: | 20452322 |
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| DOI: | 10.1038/s41598-023-30082-4 |