دورية أكاديمية
Retinal vascular impairment in Wolfram syndrome: an optical coherence tomography angiography study
| العنوان: | Retinal vascular impairment in Wolfram syndrome: an optical coherence tomography angiography study |
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| المؤلفون: | Marco Battista, Maria Lucia Cascavilla, Domenico Grosso, Enrico Borrelli, Giulio Frontino, Giulia Amore, Michele Carbonelli, Riccardo Bonfanti, Andrea Rigamonti, Costanza Barresi, Chiara Viganò, Beatrice Tombolini, Anna Crepaldi, Marina Montemagni, Chiara La Morgia, Francesco Bandello, Piero Barboni |
| المصدر: | Scientific Reports, Vol 12, Iss 1, Pp 1-8 (2022) |
| بيانات النشر: | Nature Portfolio, 2022. |
| سنة النشر: | 2022 |
| المجموعة: | LCC:Medicine LCC:Science |
| مصطلحات موضوعية: | Medicine, Science |
| الوصف: | Abstract To evaluate differences in macular and optic disc circulation in patients affected by Wolfram Syndrome (WS) employing optical coherence tomography-angiography (OCTA) imaging. In this retrospective study, 18 eyes from 10 WS patients, 16 eyes of 8 patients affected by type I diabetes and 17 eyes from 17 healthy controls were enrolled. All patients were imaged through OCT and OCTA and vascular parameters, as perfusion density (PD) and vessel length density (VLD) were measured. OCTA showed reduced PD in WS patients at the macular superficial capillary plexus (SCP, 27.8 ± 5.3%), deep vascular complex (DVC, 33.2 ± 1.9%) and optic nerve head (ONH, 21.2 ± 9.1%) compared to both diabetic patients (SCP 33.9 ± 1.9%, P |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2045-2322 |
| العلاقة: | https://doaj.org/toc/2045-2322Test |
| DOI: | 10.1038/s41598-022-06150-6 |
| الوصول الحر: | https://doaj.org/article/42ecc47043b447c5adc77d1ea7996e15Test |
| رقم الانضمام: | edsdoj.42ecc47043b447c5adc77d1ea7996e15 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 20452322 |
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| DOI: | 10.1038/s41598-022-06150-6 |