المؤلفون: Tanghöj, Gustaf, Naumburg, Estelle

المصدر: Scientific Reports; 2/27/2024, Vol. 14 Issue 1, p1-6, 6p

مصطلحات موضوعية: ATRIAL septal defects, CONGENITAL heart disease, PREMATURE labor, CHILDBIRTH, HEART failure, DOWN syndrome

مصطلحات جغرافية: SWEDEN

مستخلص: Atrial septal defect secundum is a common type of congenital heart defect and even more common among children born premature. The aim of this study was to assess premature birth as a potential associated risk factors for cardiac morbidity in children with isolated ASD II. In this retrospective national registry-based case–control study all children born in Sweden between 2010 and 2015 with an isolated ASD II diagnosis were included. Association between premature birth and cardiac morbidity in children with isolated ASD II was assessed by different outcomes-models using conditional logistic regression and adjustments were made for confounding factors. Overall, 11% of children with an isolated ASD II received treatment for heart failure. Down syndrome was the only independent risk factors for associated with cardiac morbidity in children with ASD II (OR = 2.25 (95%CI 1.25–4.07). Preterm birth in children was not associated with an increased risk of ASD II cardiac morbidity. [ABSTRACT FROM AUTHOR]

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المؤلفون: Gebreslasie, Kahsay Zenebe, Weldemariam, Solomon, Gebre, Gelawdyos, Zenebe, Dawit, Mehari, Mihreteab, Birhane, Aklil, Dewey, Rebecca Susan

المصدر: Scientific Reports; 1/16/2024, Vol. 14 Issue 1, p1-7, 7p

مصطلحات موضوعية: INTIMATE partner violence, LOW birth weight, BIRTH weight, PREGNANCY, PREMATURE labor, CHILDBIRTH, PREGNANT women

مصطلحات جغرافية: TIGRAY Kifle Hager (Ethiopia), ETHIOPIA

مستخلص: Intimate partner Violence (IPV) can affect any woman, irrespective of their economic status, religion, or culture. This is a human-rights issue and due to its prevalence and adverse effects on pregnancy and birth, it must be given greater attention. Further, there is a lack of data in the Tigray region about adverse birth outcomes due to intimate partner violence during pregnancy. The aim of this study was to assess intimate partner violence during pregnancy and its association with low birth weight and preterm birth in Tigray region. Across-sectional study design was used. 647 women were involved in the study. Simple random sampling techniques were employed to select health facilities and systematic sampling was used to select study participants. Data were entered using Epi info version 3.5.1 and was analyzed using SPSSversion 20. Logistic regression analysis was conducted to assess the association between exposure to intimate partner violence during pregnancy and preterm birth and low birth weight while adjusting for possible confounders. The prevalence of intimate partner violence during pregnancy was 7.3% and the prevalence of low birth weight and preterm birth were 18.5% and 10.8% respectively. There was a statistically significant association between exposure to intimate partner violence during pregnancy and low birth weight. After adjustment for socioeconomic status, women's habits and obstetric factors, the pregnant women who were exposed to intimate partner violence during pregnancy were two times more likely to have a child with a low birth weight (2.39 (95% CI: 1.26–4.55)). The prevalence of intimate partner violence during pregnancy, low birth weight, and preterm birth in this study was high. Women who experienced intimate partner violence during pregnancy had an increased risk of low birth weight. These findings justify a call to the federal minster of health to take measures aimed at avoiding intimate partner violence during pregnancy to reduce adverse birth outcomes. [ABSTRACT FROM AUTHOR]

: Copyright of Scientific Reports is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

المؤلفون: Girchenko, Polina¹ (AUTHOR) polina.girchenko@helsinki.fi, Robinson, Rachel¹ (AUTHOR), Rantalainen, Ville Juhani¹ (AUTHOR), Lahti-Pulkkinen, Marius^1,2,3 (AUTHOR), Heinonen-Tuomaala, Kati^1,4 (AUTHOR), Lemola, Sakari^5,6 (AUTHOR), Wolke, Dieter⁵ (AUTHOR), Schnitzlein, Daniel^7,8 (AUTHOR), Hämäläinen, Esa⁹ (AUTHOR), Laivuori, Hannele^10,11,12,13 (AUTHOR), Villa, Pia M.¹⁴ (AUTHOR), Kajantie, Eero^15,16 (AUTHOR), Räikkönen, Katri¹ (AUTHOR)

المصدر: Scientific Reports. 1/18/2022, Vol. 12 Issue 1, p1-10. 10p.

مصطلحات موضوعية: *CHILD psychiatry, *PREMATURE labor, *BEHAVIOR disorders in children, *DEPRESSION in women, *MENTAL depression, *CHILDBIRTH

مستخلص: Preterm birth has been linked with postpartum depressive (PPD) disorders and high symptom levels, but evidence remains conflicting and limited in quality. It remains unclear whether PPD symptoms of mothers with preterm babies were already elevated before childbirth, and whether PPD symptoms mediate/aggravate the effect of preterm birth on child mental disorders. We examined whether preterm birth associated with maternal PPD symptoms, depressive symptoms trajectories from antenatal to postpartum stage, and whether PPD symptoms mediated/aggravated associations between preterm birth and child mental disorders. Mothers of preterm (n = 125) and term-born (n = 3033) children of the Prediction and Prevention of Preeclampsia and Intrauterine Growth Restriction study reported depressive symptoms four times within 8 weeks before and twice within 12 months after childbirth. Child mental and behavioral disorder diagnoses until age 8.4–12.8 years came from medical register. Preterm birth associated with higher PPD symptoms (mean difference = 0.19 SD, 95% CI 0.01, 0.37, p = 0.04), and higher odds (odds ratio = 2.23, 95% CI 1.22, 4.09, p = 0.009) of the mother to belong to a group that had consistently high depressive symptoms levels trajectory from antenatal to postpartum stage. PPD symptoms partially mediated and aggravated the association between preterm birth and child mental disorders. Preterm birth, maternal PPD symptoms and child mental disorders are associated, calling for timely prevention interventions. [ABSTRACT FROM AUTHOR]

المؤلفون: Aki Yamashita, Kei Kawana, Kensuke Tomio, Ayumi Taguchi, Yosuke Isobe, Ryo Iwamoto, Koji Masuda, Hitomi Furuya, Takeshi Nagamatsu, Kazunori Nagasaka, Takahide Arimoto, Katsutoshi Oda, Osamu Wada-Hiraike, Takahiro Yamashita, Yuji Taketani, Kang, Jing X., Shiro Kozuma, Hiroyuki Arai, Makoto Arita, Yutaka Osuga

المصدر: Scientific Reports; 11/1/2013, p1-7, 7p

مصطلحات موضوعية: UNSATURATED fatty acids, CHILDBIRTH, EICOSAPENTAENOIC acid, OBSTETRICS, OMEGA-3 fatty acids, PREMATURE infants, PREMATURE labor

مستخلص: Omega-3 polyunsaturated fatty acids such as eicosapentaenoic acid (EPA) have anti-inflammatory effects. Preterm birth is an important problem in modern obstetrics and one of the main causes is an inflammation. We here showed that abundance of omega-3 fatty acids reduced the incidence of preterm birth induced by LPS with fat-1 mice, capable of converting omega-6 to omega-3 fatty acids. We also indicated that the gene expression of IL-6 and IL-1b in uteruses and the number of cervical infiltrating macrophages were reduced in fat-1 mice. The analyses of lipid metabolomics showed the high level of 18-hydroxyeicosapentaenoate in fat-1 mice, which was derived from EPA and was metabolized to anti-inflammatory product named resolvin E3 (RvE3). We finally showed that the administration of RvE3 to LPS-exposed pregnant wild type mice lowered the incidence of preterm birth. Our data suggest that RvE3 could be a potential new therapeutic for the prevention of preterm birth. [ABSTRACT FROM AUTHOR]

: Copyright of Scientific Reports is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)