يعرض 1 - 10 نتائج من 19 نتيجة بحث عن '"(1"', وقت الاستعلام: 0.75s تنقيح النتائج
  1. 1
    HCV-specific CD4+ T cells of patients with acute and chronic HCV infection display high expression of TIGIT and other co-inhibitory molecules

    المؤلفون: Silke Kummer, William W. Kwok, Thomas Jacobs, Julian Schulze zur Wiesch, Ansgar W. Lohse, Sven Peine, Matthias Marget, Tobias Boettler, Christin Ackermann, Thomas Kuntzen, Robin Woost, Maike Smits, Johanna M. Eberhard

    المصدر: Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
    Scientific Reports

    مصطلحات موضوعية: Adult, CD4-Positive T-Lymphocytes, Male, 0301 basic medicine, CD226, Programmed Cell Death 1 Receptor, BTLA, lcsh:Medicine, Hepacivirus, Immunological memory, Article, Young Adult, 03 medical and health sciences, 0302 clinical medicine, TIGIT, MHC class I, Humans, Medicine, Receptors, Immunologic, Receptor, lcsh:Science, Hepatitis A Virus Cellular Receptor 2, Aged, Multidisciplinary, biology, Hepatitis C virus, business.industry, T-cell receptor, lcsh:R, Histocompatibility Antigens Class II, virus diseases, Hepatitis C, Chronic, Middle Aged, Receptors, OX40, Hepatitis C, digestive system diseases, Chronic infection, 030104 developmental biology, Acute Disease, Immunology, biology.protein, Female, lcsh:Q, business, 030217 neurology & neurosurgery, CD8

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df54b52b1f824ed57f6415d962a118eaTest
    http://link.springer.com/article/10.1038/s41598-019-47024-8Test


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  2. 2
    Immunoprofiling of Colitis-associated and Sporadic Colorectal Cancer and its Clinical Significance

    المؤلفون: Jeong-Sik Byeon, Sang-Yeob Kim, Su In Jo, Jae Seung Soh, Sung Wook Hwang, Dong-Hoon Yang, Suk-Kyun Yang, Jihun Kim, Sang Hyoung Park, Eun-Ju Do, Hye Jin Lee, Seung-Jae Myung, Byong Duk Ye

    المصدر: Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
    Scientific Reports

    مصطلحات موضوعية: 0301 basic medicine, Oncology, Cancer microenvironment, Adult, Male, medicine.medical_specialty, CD3 Complex, medicine.medical_treatment, Programmed Cell Death 1 Receptor, lcsh:Medicine, CD8-Positive T-Lymphocytes, Article, 03 medical and health sciences, 0302 clinical medicine, Immune system, Internal medicine, Neoplasms, Medicine, Humans, Clinical significance, cardiovascular diseases, Colitis, lcsh:Science, Aged, Multidisciplinary, business.industry, lcsh:R, FOXP3, Cancer, nutritional and metabolic diseases, Forkhead Transcription Factors, Immunotherapy, Middle Aged, medicine.disease, Immunohistochemistry, Colon cancer, 030104 developmental biology, Female, lcsh:Q, business, Colorectal Neoplasms, 030217 neurology & neurosurgery, CD8

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f57b8b93981a47c773eff93736694474Test
    http://link.springer.com/article/10.1038/s41598-019-42986Test-1


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  3. 3
    Continuous monitoring of neutrophils to lymphocytes ratio for estimating the onset, severity, and subsequent prognosis of immune related adverse events

    المؤلفون: Kojiro Hata, Takashi Nakagawa, Ryosuke Matsukane, Masatoshi Eto, Haruna Minami, Nobuaki Egashira, Kimitaka Suetsugu, Isamu Okamoto, Masaki Mori, Satohiro Masuda, Takamichi Ito, Hiroyuki Watanabe, Toshikazu Tsuji, Yoichi Nakanishi

    المصدر: Scientific Reports
    Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)

    مصطلحات موضوعية: 0301 basic medicine, Adult, Male, medicine.medical_specialty, Adolescent, Neutrophils, Science, Programmed Cell Death 1 Receptor, Gastroenterology, Article, 03 medical and health sciences, 0302 clinical medicine, Immune system, Internal medicine, Neoplasms, medicine, Biomarkers, Tumor, Humans, Lymphocytes, Adverse effect, Immune Checkpoint Inhibitors, Pneumonitis, Aged, Retrospective Studies, Aged, 80 and over, Multidisciplinary, Receiver operating characteristic, business.industry, Hazard ratio, fungi, Cancer, Retrospective cohort study, Middle Aged, medicine.disease, Neoplasm Proteins, 030104 developmental biology, Oncology, 030220 oncology & carcinogenesis, Biomarker (medicine), Medicine, Female, business, Biomarkers

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fd44ea4bfa5176e1264d8c08fe5da99Test
    http://europepmc.org/articles/PMC7809015Test


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  4. 4
    Quantitative and functional characteristics of circulating and bone marrow PD-1- and TIM-3-positive T cells in treated multiple myeloma patients

    المؤلفون: Vera V. Sergeevicheva, Egor V. Batorov, Tatiana A. Aristova, Galina Y. Ushakova, Irina V Shishkova, Alexander A. Ostanin, Elena R. Chernykh, Svetlana A. Sizikova, N. V. Pronkina, Ekaterina Ya. Shevela

    المصدر: Scientific Reports

    مصطلحات موضوعية: 0301 basic medicine, Adult, Male, T cell, Programmed Cell Death 1 Receptor, Double negative, Myeloma, CD8-Positive T-Lymphocytes, Granzymes, Article, Immunophenotyping, 03 medical and health sciences, Interferon-gamma, 0302 clinical medicine, Bone Marrow, T-Lymphocyte Subsets, medicine, Cytotoxic T cell, Humans, Multiple myeloma, Multidisciplinary, Chemistry, Middle Aged, medicine.disease, Molecular biology, Granzyme B, 030104 developmental biology, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Tumour immunology, Female, Bone marrow, Multiple Myeloma, Intracellular, CD8

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e93de12d5815bda00dc8e3a37eccf5c3Test
    https://pubmed.ncbi.nlm.nih.gov/33257767Test


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  5. 5
    Risk factors of immune checkpoint inhibitor-related interstitial lung disease in patients with lung cancer: a single-institution retrospective study

    المؤلفون: Mitsuhiro Goda, Keisuke Ishizawa, Masayuki Chuma, Rie Matsuoka, Kenta Yagi, Yasuhiko Nishioka, Naoto Okada, Takumi Sakurada, Yoshito Zamami

    المصدر: Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
    Scientific Reports

    مصطلحات موضوعية: Male, 0301 basic medicine, Oncology, Lung Neoplasms, Programmed Cell Death 1 Receptor, lcsh:Medicine, B7-H1 Antigen, 0302 clinical medicine, Carcinoma, Non-Small-Cell Lung, CTLA-4 Antigen, lcsh:Science, Immune Checkpoint Inhibitors, Aged, 80 and over, Multidisciplinary, Incidence (epidemiology), Mortality rate, Interstitial lung disease, Antibodies, Monoclonal, Middle Aged, respiratory system, Nivolumab, Female, Risk assessment, hormones, hormone substitutes, and hormone antagonists, Adult, medicine.medical_specialty, Antibodies, Monoclonal, Humanized, Risk Assessment, behavioral disciplines and activities, Article, 03 medical and health sciences, Internal medicine, Carcinoma, medicine, Humans, Lung cancer, Adverse effect, Aged, Retrospective Studies, business.industry, lcsh:R, Retrospective cohort study, medicine.disease, respiratory tract diseases, body regions, Early Diagnosis, 030104 developmental biology, Risk factors, lcsh:Q, Lung Diseases, Interstitial, business, 030217 neurology & neurosurgery

    وصف الملف: application/pdf

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe7819bf7544453aee274331eacf36bbTest
    https://doi.org/10.1038/s41598-020-70743-2Test


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  6. 6
    Differential expression of individual transcript variants of PD-1 and PD-L2 genes on Th-1/Th-2 status is guaranteed for prognosis prediction in PCNSL

    المؤلفون: Junya Fukai, Hiroaki Hondoh, Atsushi Kawaguchi, Jumpei Homma, Ryuya Yamanaka, Ryuichi Sato, Masakazu Nakano, Seishi Ogawa, Kei Tashiro, Kenichi Yoshida, Yasuo Takashima, Koji Kajiwara, Yasuo Iwadate, Azusa Hayano, Shin Ishizawa

    المصدر: Scientific Reports
    Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)

    مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Science, T cell, Programmed Cell Death 1 Receptor, Biology, HAVCR2, Article, Central Nervous System Neoplasms, Prognostic markers, 03 medical and health sciences, Th2 Cells, 0302 clinical medicine, Gene expression, medicine, Humans, Gene, Aged, Aged, 80 and over, Multidisciplinary, Sequence Analysis, RNA, Gene Expression Profiling, Statistics, Primary central nervous system lymphoma, High-Throughput Nucleotide Sequencing, Cancer, Middle Aged, Th1 Cells, Prognosis, Programmed Cell Death 1 Ligand 2 Protein, medicine.disease, Molecular medicine, Immune checkpoint, Up-Regulation, Gene Expression Regulation, Neoplastic, CNS cancer, 030104 developmental biology, medicine.anatomical_structure, Risk factors, Cancer research, Medicine, Female, Lymphoma, Large B-Cell, Diffuse, 030217 neurology & neurosurgery

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b6dc115c09b762750c955588f123db7Test
    https://doi.org/10.1038/s41598-019-46473-5Test


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  7. 7
    Risk factors for immune-related adverse events associated with anti-PD-1 pembrolizumab

    المؤلفون: Jaejoon Lee, Jeeyun Lee, Jong-Mu Sun, Yeonghee Eun, Hoon-Suk Cha, Hyung-Jin Kim, Eun-Mi Koh, In Young Kim

    المصدر: Scientific Reports
    Scientific Reports, Vol 9, Iss 1, Pp 1-8 (2019)

    مصطلحات موضوعية: 0301 basic medicine, Adult, Male, medicine.medical_specialty, Cancer therapy, Adolescent, Programmed Cell Death 1 Receptor, lcsh:Medicine, Cancer immunotherapy, Pembrolizumab, Logistic regression, Antibodies, Monoclonal, Humanized, Endocrine System Diseases, Skin Diseases, Article, 03 medical and health sciences, Young Adult, 0302 clinical medicine, Antineoplastic Agents, Immunological, Risk Factors, Internal medicine, Republic of Korea, medicine, Humans, Musculoskeletal Diseases, lcsh:Science, Adverse effect, Pneumonitis, Aged, Retrospective Studies, Aged, 80 and over, Multidisciplinary, business.industry, lcsh:R, Retrospective cohort study, Odds ratio, Pneumonia, Middle Aged, medicine.disease, Confidence interval, 030104 developmental biology, Logistic Models, 030220 oncology & carcinogenesis, lcsh:Q, Female, business, Body mass index

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5764bab20dbe34003e8175b6f14120e2Test
    http://europepmc.org/articles/PMC6773778Test


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  8. 8
    Real-world evidence and clinical observations of the treatment of advanced non-small cell lung cancer with PD-1/PD-L1 inhibitors

    المؤلفون: Congcong Shang, Li Zhang, Jingcheng Zhang, Peng Song

    المصدر: Scientific Reports
    Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)

    مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Oncology, medicine.medical_specialty, Lung Neoplasms, medicine.medical_treatment, Programmed Cell Death 1 Receptor, lcsh:Medicine, Kaplan-Meier Estimate, Article, B7-H1 Antigen, 03 medical and health sciences, 0302 clinical medicine, T-Lymphocyte Subsets, Carcinoma, Non-Small-Cell Lung, Positron Emission Tomography Computed Tomography, Internal medicine, medicine, Humans, Outpatient clinic, Enzyme Inhibitors, lcsh:Science, Author Correction, Lung cancer, Survival analysis, Aged, Aged, 80 and over, Multidisciplinary, business.industry, lcsh:R, Therapeutic effect, Immunotherapy, Middle Aged, medicine.disease, Magnetic Resonance Imaging, Progression-Free Survival, ErbB Receptors, Clinical trial, 030104 developmental biology, Response Evaluation Criteria in Solid Tumors, lcsh:Q, Female, business, 030217 neurology & neurosurgery, Progressive disease

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cd88b18ed3f11ab3578a828394394f6Test
    https://doi.org/10.1038/s41598-019-40748-7Test


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  9. 9
    Impaired activation of lesional CD8+ T-cells is associated with enhanced expression of Programmed Death-1 in Indian Post Kala-azar Dermal Leishmaniasis

    المؤلفون: Ritika Sengupta, Debanjan Mukhopadhyay, Esther von Stebut, Mitali Chatterjee, Nilay Kanti Das, Shibabrata Mukherjee, Susmita Roy, Uttara Chatterjee, Claudia Braun, Sneha Mitra

    المصدر: Scientific Reports
    Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)

    مصطلحات موضوعية: Male, 0301 basic medicine, Disease reservoir, Programmed Cell Death 1 Receptor, lcsh:Medicine, CD8-Positive T-Lymphocytes, Monocytes, 0302 clinical medicine, Medicine, lcsh:Science, education.field_of_study, ZAP-70 Protein-Tyrosine Kinase, Multidisciplinary, biology, integumentary system, Interleukin-10, Interleukin 10, Leishmaniasis, Visceral, Female, Adult, Receptors, CCR4, Adolescent, Population, Leishmania donovani, Article, Interleukin-7 Receptor alpha Subunit, Young Adult, 03 medical and health sciences, Immune system, parasitic diseases, Humans, Author Correction, education, Post-kala-azar dermal leishmaniasis, Perforin, business.industry, Macrophages, lcsh:R, medicine.disease, biology.organism_classification, 030104 developmental biology, Visceral leishmaniasis, Gene Expression Regulation, Granzyme, Immunology, biology.protein, lcsh:Q, Chemokine CCL17, business, 030217 neurology & neurosurgery

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d68163300d4edcd29ceead4a7f230f11Test
    http://europepmc.org/articles/PMC6345993Test


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  10. 10
    Analysis of expression of the PD-1/PD-L1 immune checkpoint system and its prognostic impact in gastroenteropancreatic neuroendocrine tumors

    المؤلفون: Rebeca Martínez-Hernández, Mónica Marazuela, Ana Serrano-Somavilla, Rogelio García-Centeno, Concepción Blanco-Carrera, José Luis Muñoz de Nova, Ihab Abdulkader, Elena Martín-Pérez, José A. Díaz, José Manuel Cabezas-Agrícola, Magdalena Adrados, Javier Caneiro-Gómez, Miguel Sampedro-Núñez, José Cameselle-Teijeiro, Roberto González-Amaro

    المساهمون: Universidade de Santiago de Compostela. Departamento de Ciencias Forenses, Anatomía Patolóxica, Xinecoloxía e Obstetricia, e Pediatría

    المصدر: Scientific Reports
    Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
    Consejería de Sanidad de la Comunidad de Madrid
    Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
    instname
    Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)

    مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Programmed Cell Death 1 Receptor, lcsh:Medicine, Context (language use), Neuroendocrine tumors, Peripheral blood mononuclear cell, Article, B7-H1 Antigen, Flow cytometry, 03 medical and health sciences, 0302 clinical medicine, Stomach Neoplasms, PD-L1, Intestinal Neoplasms, medicine, Humans, lcsh:Science, Aged, Retrospective Studies, Multidisciplinary, medicine.diagnostic_test, biology, business.industry, lcsh:R, Middle Aged, Prognosis, medicine.disease, Immune checkpoint, Neoplasm Proteins, Gene Expression Regulation, Neoplastic, Pancreatic Neoplasms, Neuroendocrine Tumors, 030104 developmental biology, 030220 oncology & carcinogenesis, Cancer research, biology.protein, Immunohistochemistry, lcsh:Q, Female, business, Progressive disease

    وصف الملف: application/pdf

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5fd66ff35f294aa7ac1863c50bf418fTest
    https://doi.org/10.1038/s41598-018-36129Test-1


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