المؤلفون: Scott, Robert A, Freitag, Daniel F, Li, Li, Chu, Audrey Y, Surendran, Praveen, Young, Robin, Grarup, Niels, Stancáková, Alena, Chen, Yuning, Varga, Tibor V, Yaghootkar, Hanieh, Luan, Jian’an, Zhao, Jing Hua, Willems, Sara M, Wessel, Jennifer, Wang, Shuai, Maruthur, Nisa, Michailidou, Kyriaki, Pirie, Ailith, van der Lee, Sven J, Gillson, Christopher, Al Olama, Ali Amin, Amouyel, Philippe, Arriola, Larraitz, Arveiler, Dominique, Aviles-Olmos, Iciar, Balkau, Beverley, Barricarte, Aurelio, Barroso, Inês, Garcia, Sara Benlloch, Bis, Joshua C, Blankenberg, Stefan, Boehnke, Michael, Boeing, Heiner, Boerwinkle, Eric, Borecki, Ingrid B, Bork-Jensen, Jette, Bowden, Sarah, Caldas, Carlos, Caslake, Muriel, consortium, The CVD50, Cupples, L Adrienne, Cruchaga, Carlos, Czajkowski, Jacek, Hoed, Marcel den, Dunn, Janet A, Earl, Helena M, Ehret, Georg B, Ferrannini, Ele, Ferrieres, Jean, Foltynie, Thomas, Ford, Ian, Forouhi, Nita G, Gianfagna, Francesco, Gonzalez, Carlos, Grioni, Sara, Hiller, Louise, Jansson, Jan-Håkan, Jørgensen, Marit E, Jukema, J Wouter, Kaaks, Rudolf, Kee, Frank, Kerrison, Nicola D, Key, Timothy J, Kontto, Jukka, Kote-Jarai, Zsofia, Kraja, Aldi T, Kuulasmaa, Kari, Kuusisto, Johanna, Linneberg, Allan, Liu, Chunyu, Marenne, Gaëlle, Mohlke, Karen L, Morris, Andrew P, Muir, Kenneth, Müller-Nurasyid, Martina, Munroe, Patricia B, Navarro, Carmen, Nielsen, Sune F, Nilsson, Peter M, Nordestgaard, Børge G, Packard, Chris J, Palli, Domenico, Panico, Salvatore, Peloso, Gina M, Perola, Markus, Peters, Annette, Poole, Christopher J, Quirós, J Ramón, Rolandsson, Olov, Sacerdote, Carlotta, Salomaa, Veikko, Sánchez, María-José, Sattar, Naveed, Sharp, Stephen J, Sims, Rebecca, Slimani, Nadia, Smith, Jennifer A, Thompson, Deborah J, Trompet, Stella

المصدر: Science Translational Medicine. 8(341)

مصطلحات موضوعية: Pharmacology and Pharmaceutical Sciences, Biomedical and Clinical Sciences, Clinical Research, Diabetes, Human Genome, Cardiovascular, Prevention, Obesity, Genetics, Heart Disease, Heart Disease - Coronary Heart Disease, Clinical Trials and Supportive Activities, Aetiology, Development of treatments and therapeutic interventions, 5.1 Pharmaceuticals, 2.1 Biological and endogenous factors, Metabolic and endocrine, Good Health and Well Being, Alleles, Coronary Disease, Diabetes Mellitus, Type 2, Dipeptidyl Peptidase 4, Genotype, Glucagon-Like Peptide-1 Receptor, Humans, Receptor, Cannabinoid, CB2, Receptor, Serotonin, 5-HT2C, Receptors, Somatostatin, Sodium-Glucose Transporter 1, CVD50 consortium, GERAD_EC Consortium, Neurology Working Group of the Cohorts for Heart, Aging Research in Genomic Epidemiology, Alzheimer’s Disease Genetics Consortium, Pancreatic Cancer Cohort Consortium, European Prospective Investigation into Cancer and Nutrition–Cardiovascular Disease, EPIC-InterAct, CHARGE consortium, CHD Exome+ Consortium, CARDIOGRAM Exome Consortium, Biological Sciences, Medical and Health Sciences, Medical biotechnology, Biomedical engineering

الوصول الحر: https://escholarship.org/uc/item/0zq8d76wTest

المؤلفون: Brandon C. P. Clavette, Xiaoshan Min, Joanne Lin, Elizabeth A. Killion, Robert J.M. Kurzeja, David Lloyd, Liying Deng, Zhulun Wang, Clarence Hale, Christopher Murawsky, Stone D.-H. Shi, Murielle M. Véniant, Jinghong Wang, James B. Rottman, Christina Abbott, Todd Hager, Lu Shu Chen, Junming Yie, Ian Foltz, Qing Chen, Stephen A. Thibault, Darren L. Bates, Renee Komorowski, Larissa Atangan, Glenn Sivits, Tina Meng

المصدر: Science Translational Medicine. 10

مصطلحات موضوعية: Primates, 0301 basic medicine, endocrine system, medicine.medical_specialty, Recombinant Fusion Proteins, Glucagon-Like Peptides, Mice, Obese, Genome-wide association study, Gastric Inhibitory Polypeptide, Weight Gain, Antibodies, Glucagon-Like Peptide-1 Receptor, Receptors, Gastrointestinal Hormone, 03 medical and health sciences, 0302 clinical medicine, Weight loss, Insulin-Secreting Cells, Internal medicine, Weight Loss, Conditional gene knockout, Adipocytes, Animals, Humans, Medicine, Obesity, Receptor, Respiratory exchange ratio, biology, business.industry, Respiration, Feeding Behavior, General Medicine, Liraglutide, medicine.disease, Diet, Immunoglobulin Fc Fragments, 030104 developmental biology, Endocrinology, 030220 oncology & carcinogenesis, Knockout mouse, biology.protein, Drug Therapy, Combination, medicine.symptom, Antibody, business, hormones, hormone substitutes, and hormone antagonists

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4219a5cd6927493203264b2541e2f88bTest
https://doi.org/10.1126/scitranslmed.aat3392Test

المؤلفون: Kim G. Madsen, Flemming L. Søndergaard, Jonas Ahnfelt-Rønne, Andrew J. Benie, Simon Bjerregaard, Jeanett Borregaard, Tine A. Bækdal, Betty Lomstein Pedersen, Susanne Schéele, Charles Pyke, Marie-Louise Hartoft-Nielsen, Stephen T. Buckley, Tomas Alanentalo, Rikke Bjerring Skyggebjerg, Rikke Kaae Kirk, Lotte Bjerre Knudsen, Stine J. Maarbjerg, Holger M. Strauss, Andreas Vegge, Csaba Fekete, Erzsébet Farkas, Per-Olof Wahlund

المصدر: Science Translational Medicine. 10

مصطلحات موضوعية: Adult, Male, Absorption (pharmacology), Time Factors, Adolescent, Glucagon-Like Peptides, Administration, Oral, 02 engineering and technology, Pharmacology, 030226 pharmacology & pharmacy, Glucagon-Like Peptide-1 Receptor, Intestinal absorption, Young Adult, 03 medical and health sciences, Dogs, 0302 clinical medicine, Glucagon-Like Peptide 1, Oral administration, Animals, Humans, Transcellular, Glucagon-like peptide 1 receptor, Aged, Tight junction, Chemistry, Semaglutide, Cell Membrane, Stomach, Proteolytic enzymes, Epithelial Cells, General Medicine, Hydrogen-Ion Concentration, Middle Aged, 021001 nanoscience & nanotechnology, Rats, Intestinal Absorption, Gastric Mucosa, 0210 nano-technology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da23aec5d09c52d95e43b0ca9e999cdbTest
https://doi.org/10.1126/scitranslmed.aar7047Test

المؤلفون: James L Mitchell, Rigmor Jensen, Maria Uldall, Alexandra J Sinclair, Snorre Malm Hagen, David J. Hodson, Hannah Botfield, Ana Maria Gonzalez, Connar Westgate

المصدر: Science Translational Medicine. 9

مصطلحات موضوعية: 0301 basic medicine, Agonist, endocrine system, medicine.medical_specialty, Consciousness, Intracranial Pressure, medicine.drug_class, Glucagon-Like Peptide-1 Receptor, Rats, Sprague-Dawley, 03 medical and health sciences, 0302 clinical medicine, Cerebrospinal fluid, Internal medicine, Cyclic AMP, medicine, Animals, Humans, RNA, Messenger, Receptor, Glucagon-like peptide 1 receptor, Intracranial pressure, Kidney, Venoms, business.industry, digestive, oral, and skin physiology, Antagonist, General Medicine, 3. Good health, Disease Models, Animal, 030104 developmental biology, medicine.anatomical_structure, Endocrinology, Postmortem Changes, Choroid Plexus, Exenatide, Female, Choroid plexus, Sodium-Potassium-Exchanging ATPase, Peptides, business, hormones, hormone substitutes, and hormone antagonists, 030217 neurology & neurosurgery, Hydrocephalus

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87911b2ba2bdba79994b9b14a26bd5fbTest
https://doi.org/10.1126/scitranslmed.aan0972Test

المؤلفون: Michele Lau, Kirk M. Habegger, Emmanuelle Hainaut, Louis Vignati, Susanna M. Hofmann, David L. Smiley, Nickki Ottaway, Diego Perez-Tilve, Richard D. DiMarchi, Sarah Kathleen Haas Lockie, Elena Sebokova, Paul T. Pfluger, Lianshan Zhang, Vasily M. Gelfanov, William Riboulet, Brian Finan, Kristy M. Heppner, Bin Yang, Matthias H. Tschöp, Dennis Bruemmer, Jazzminn Hembree, Daniel J. Drucker, Jonathan Hauptman, Jaswant Gidda, Jenna Holland, Sabine Uhles, Karin Conde-Knape, Timo D. Müller, Henriette Kirchner, Tao Ma, Christine Raver, Anish Konkar, Mathieu Brecheisen

المصدر: Science translational medicine. 5(209)

مصطلحات موضوعية: Male, Acylation, Pharmacology, Mice, Glucagon-Like Peptide 1, Receptors, Glucagon, Medicine, Insulin, Receptor, Glucose tolerance test, medicine.diagnostic_test, digestive, oral, and skin physiology, General Medicine, Haplorhini, Middle Aged, Treatment Outcome, Gastrointestinal hormone, Female, hormones, hormone substitutes, and hormone antagonists, medicine.drug, Agonist, Adult, endocrine system, medicine.medical_specialty, Adolescent, medicine.drug_class, Incretin, Rodentia, Gastric Inhibitory Polypeptide, Incretins, Glucagon-Like Peptide-1 Receptor, Receptors, Gastrointestinal Hormone, Young Adult, Insulin resistance, Internal medicine, Weight Loss, Animals, Humans, Aged, business.industry, Liraglutide, Venoms, Glucose Tolerance Test, medicine.disease, Rats, Endocrinology, Diabetes Mellitus, Type 2, Hyperglycemia, Exenatide, business, Peptides

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1deb1be5ea21c3d6fd22b8faa196937Test
https://pubmed.ncbi.nlm.nih.gov/24336503Test