المؤلفون: Jones, Robert C, Karkanias, Jim, Krasnow, Mark A, Pisco, Angela Oliveira, Quake, Stephen R, Salzman, Julia, Yosef, Nir, Bulthaup, Bryan, Brown, Phillip, Harper, William, Hemenez, Marisa, Ponnusamy, Ravikumar, Salehi, Ahmad, Sanagavarapu, Bhavani A, Spallino, Eileen, Aaron, Ksenia A, Concepcion, Waldo, Gardner, James M, Kelly, Burnett, Neidlinger, Nikole, Wang, Zifa, Crasta, Sheela, Kolluru, Saroja, Morri, Maurizio, Tan, Serena Y, Travaglini, Kyle J, Xu, Chenling, Alcántara-Hernández, Marcela, Almanzar, Nicole, Antony, Jane, Beyersdorf, Benjamin, Burhan, Deviana, Calcuttawala, Kruti, Carter, Matthew M, Chan, Charles KF, Chang, Charles A, Chang, Stephen, Colville, Alex, Culver, Rebecca N, Cvijović, Ivana, D'Amato, Gaetano, Ezran, Camille, Galdos, Francisco X, Gillich, Astrid, Goodyer, William R, Hang, Yan, Hayashi, Alyssa, Houshdaran, Sahar, Huang, Xianxi, Irwin, Juan C, Jang, SoRi, Juanico, Julia Vallve, Kershner, Aaron M, Kim, Soochi, Kiss, Bernhard, Kong, William, Kumar, Maya E, Kuo, Angera H, Li, Baoxiang, Loeb, Gabriel B, Lu, Wan-Jin, Mantri, Sruthi, Markovic, Maxim, McAlpine, Patrick L, de Morree, Antoine, Mrouj, Karim, Mukherjee, Shravani, Muser, Tyler, Neuhöfer, Patrick, Nguyen, Thi D, Perez, Kimberly, Puluca, Nazan, Qi, Zhen, Rao, Poorvi, Raquer-McKay, Hayley, Schaum, Nicholas, Scott, Bronwyn, Seddighzadeh, Bobak, Segal, Joe, Sen, Sushmita, Sikandar, Shaheen, Spencer, Sean P, Steffes, Lea C, Subramaniam, Varun R, Swarup, Aditi, Swift, Michael, Van Treuren, Will, Trimm, Emily, Veizades, Stefan, Vijayakumar, Sivakamasundari, Vo, Kim Chi, Vorperian, Sevahn K, Wang, Wanxin, Weinstein, Hannah NW, Winkler, Juliane, Wu, Timothy TH, Xie, Jamie, Yung, Andrea R, Zhang, Yue, Detweiler, Angela M

المصدر: Science. 376(6594)

مصطلحات موضوعية: Biological Sciences, Bioinformatics and Computational Biology, Genetics, Human Genome, Generic health relevance, Atlases as Topic, B-Lymphocytes, Cells, Humans, Organ Specificity, RNA Splicing, Single-Cell Analysis, T-Lymphocytes, Transcriptome, Tabula Sapiens Consortium*, General Science & Technology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/0285358rTest
https://escholarship.org/content/qt0285358r/qt0285358r.pdfTest

المؤلفون: Winkler, Ethan A, Kim, Chang N, Ross, Jayden M, Garcia, Joseph H, Gil, Eugene, Oh, Irene, Chen, Lindsay Q, Wu, David, Catapano, Joshua S, Raygor, Kunal, Narsinh, Kazim, Kim, Helen, Weinsheimer, Shantel, Cooke, Daniel L, Walcott, Brian P, Lawton, Michael T, Gupta, Nalin, Zlokovic, Berislav V, Chang, Edward F, Abla, Adib A, Lim, Daniel A, Nowakowski, Tomasz J

المصدر: Science. 375(6584)

مصطلحات موضوعية: Biomedical and Clinical Sciences, Immunology, Stem Cell Research, Stem Cell Research - Nonembryonic - Human, Neurosciences, Brain Disorders, Stroke, 1.1 Normal biological development and functioning, Aetiology, 2.1 Biological and endogenous factors, Underpinning research, Adult, Blood Vessels, Brain, Cells, Cultured, Cerebral Cortex, Cerebral Hemorrhage, Cerebrovascular Circulation, Endothelial Cells, Fibroblasts, Humans, Inflammation, Intracranial Arteriovenous Malformations, Monocytes, Muscle, Smooth, Vascular, Pericytes, RNA-Seq, Single-Cell Analysis, Transcriptome, General Science & Technology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/2gg255fbTest

المؤلفون: Krumm, Niklas, Huddleston, John, Coe, Bradley, Baker, Carl, Nordenfelt, Susanne, Bamshad, Michael, Jorde, Lynn, Posukh, Olga, Sahakyan, Hovhannes, Watkins, W, Yepiskoposyan, Levon, Abdullah, M, Bravi, Claudio, Capelli, Cristian, Hervig, Tor, Wee, Joseph, Tyler-Smith, Chris, van Driem, George, Romero, Irene, Jha, Aashish, Karachanak-Yankova, Sena, Toncheva, Draga, Comas, David, Kivisild, Toomas, Ruiz-Linares, Andres, Sajantila, Antti, Metspalu, Ene, Parik, Jüri, Villems, Richard, Starikovskaya, Elena, Ayodo, George, Beall, Cynthia, Di Rienzo, Anna, Hammer, Michael, Khusainova, Rita, Khusnutdinova, Elza, Klitz, William, Winkler, Cheryl, Labuda, Damian, Metspalu, Mait, Tishkoff, Sarah, Dryomov, Stanislav, Sukernik, Rem, Patterson, Nick, Reich, David, Eichler, Evan, Mallick, Swapan, Nelson, Bradley, Hormozdiari, Fereydoun, Henn, Brenna, Sudmant, Peter

المصدر: Science. 349(6253)

مصطلحات موضوعية: Animals, Black People, DNA Copy Number Variations, Evolution, Molecular, Gene Duplication, Genome, Human, Hominidae, Humans, Native Hawaiian or Other Pacific Islander, Phylogeny, Polymorphism, Single Nucleotide, Population, Selection, Genetic, Sequence Deletion

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/02p8q93cTest

المؤلفون: Sudmant, Peter H, Mallick, Swapan, Nelson, Bradley J, Hormozdiari, Fereydoun, Krumm, Niklas, Huddleston, John, Coe, Bradley P, Baker, Carl, Nordenfelt, Susanne, Bamshad, Michael, Jorde, Lynn B, Posukh, Olga L, Sahakyan, Hovhannes, Watkins, W Scott, Yepiskoposyan, Levon, Abdullah, M Syafiq, Bravi, Claudio M, Capelli, Cristian, Hervig, Tor, Wee, Joseph TS, Tyler-Smith, Chris, van Driem, George, Romero, Irene Gallego, Jha, Aashish R, Karachanak-Yankova, Sena, Toncheva, Draga, Comas, David, Henn, Brenna, Kivisild, Toomas, Ruiz-Linares, Andres, Sajantila, Antti, Metspalu, Ene, Parik, Jüri, Villems, Richard, Starikovskaya, Elena B, Ayodo, George, Beall, Cynthia M, Di Rienzo, Anna, Hammer, Michael F, Khusainova, Rita, Khusnutdinova, Elza, Klitz, William, Winkler, Cheryl, Labuda, Damian, Metspalu, Mait, Tishkoff, Sarah A, Dryomov, Stanislav, Sukernik, Rem, Patterson, Nick, Reich, David, Eichler, Evan E

المصدر: Science. 349(6253)

مصطلحات موضوعية: Genetics, Human Genome, Animals, Black People, DNA Copy Number Variations, Evolution, Molecular, Gene Duplication, Genome, Human, Hominidae, Humans, Native Hawaiian or Other Pacific Islander, Phylogeny, Polymorphism, Single Nucleotide, Population, Selection, Genetic, Sequence Deletion, General Science & Technology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/0217q99xTest

المؤلفون: Teemu Smura, Frederic A. Meunier, Minou Djannatian, Jonas Franz, Martin Sebastian Winkler, Christine Stadelmann, Leonora Szirovicza, Brit Mollenhauer, Ari Helenius, Pamela Österlund, Olli Vapalahti, Tuğberk Kaya, Sarah J. Butcher, Maria Anastasina, Lev Levanov, Ravi Ojha, Suvi Kuivanen, Ludovico Cantuti-Castelvetri, Mikael Simons, Hannimari Kallio-Kokko, Ozgun Gokce, Giuseppe Balistreri, Katri Kallio, Merja Joensuu, Liliana D. Pedro, Allan Tobi, Franziska van der Meer, Tambet Teesalu, Jussi Hepojoki

المساهمون: Molecular and Integrative Biosciences Research Programme, Viral Zoonosis Research Unit, Department of Virology, Medicum, Macromolecular structure and function, Institute of Biotechnology, Helsinki Institute of Life Science HiLIFE, HUSLAB, Biosciences, Helsinki One Health (HOH), Veterinary Microbiology and Epidemiology, Veterinary Biosciences, Olli Pekka Vapalahti / Principal Investigator, Helsinki Institute of Sustainability Science (HELSUS), University of Zurich, Balistreri, Giuseppe, Simons, Mikael

المصدر: Science
Science, 370 (6518)
Science (New York, N.y.)
Science / Science now 370(6518), 856-860 (2020). doi:10.1126/science.abd2985
Signal Transduction and Targeted Therapy

مصطلحات موضوعية: Male, virology [Pneumonia, Viral], Ace2 protein, mouse, viruses, PROTEIN, Metal Nanoparticles, genetics [Peptidyl-Dipeptidase A], genetics [Serine Endopeptidases], Mice, 0302 clinical medicine, Neuropilin 1, SPIKE, immunology [Neuropilin-1], metabolism [Peptide Fragments], physiology [Betacoronavirus], skin and connective tissue diseases, Furin, Lung, virology [Coronavirus Infections], Infectivity, 11832 Microbiology and virology, 0303 health sciences, chemistry [Neuropilin-1], Multidisciplinary, biology, Serine Endopeptidases, Antibodies, Monoclonal, virus diseases, spike protein, SARS-CoV-2, Microbio, Research Highlight, NRP1 protein, human, 3. Good health, medicine.anatomical_structure, virology [Olfactory Mucosa], Spike Glycoprotein, Coronavirus, Infectious diseases, VIRUS, Female, Angiotensin-Converting Enzyme 2, Antibody, Coronavirus Infections, Protein Binding, neuropilin-2, human, chemistry [Spike Glycoprotein, Coronavirus], Pneumonia, Viral, 10184 Institute of Veterinary Pathology, ACE2 protein, human, Respiratory Mucosa, Peptidyl-Dipeptidase A, metabolism [Lung], Virus, 03 medical and health sciences, Betacoronavirus, Medical research, Olfactory Mucosa, Protein Domains, metabolism [Respiratory Mucosa], metabolism [Serine Endopeptidases], Report, medicine, Animals, Humans, metabolism [Neuropilin-2], metabolism [Peptidyl-Dipeptidase A], genetics [Betacoronavirus], Pandemics, 030304 developmental biology, 1000 Multidisciplinary, Host Microbial Interactions, SARS-CoV-2, HEK 293 cells, fungi, COVID-19, genetics [Neuropilin-1], Virus Internalization, Virology, Peptide Fragments, Neuropilin-1, Neuropilin-2, Mice, Inbred C57BL, metabolism [Olfactory Mucosa], immunology [Antibodies, Monoclonal], HEK293 Cells, TMPRSS2 protein, human, metabolism [Spike Glycoprotein, Coronavirus], ddc:320, Mutation, biology.protein, Tissue tropism, 570 Life sciences, Caco-2 Cells, metabolism [Neuropilin-1], Cell Biol, Olfactory epithelium, 030217 neurology & neurosurgery, Reports

وصف الملف: application/application/pdf; ZORA202286.pdf - application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30d602d02c0f3dd0c2860bc58f052583Test

المؤلفون: Efi E. Massasa, Shalev Itzkovitz, Roni Winkler, Rom Shenhav, Orel Mizrahi, Noam Stern-Ginossar, Shaked Baydatch, Ofra Golani, Andreas E. Moor, Matan Golan, Tomer Weizman, Doron Lemze

المصدر: Science. 357:1299-1303

مصطلحات موضوعية: Male, Ribosomal Proteins, 0301 basic medicine, Biology, Ribosome, Article, Intestinal absorption, Mice, 03 medical and health sciences, Ribosomal protein, P-bodies, Protein biosynthesis, Humans, Animals, RNA, Messenger, Intestinal Mucosa, RNA Processing, Post-Transcriptional, Messenger RNA, Multidisciplinary, Translation (biology), Fasting, Molecular biology, Protein subcellular localization prediction, Single Molecule Imaging, Cell biology, Mice, Inbred C57BL, Protein Transport, 030104 developmental biology, Intestinal Absorption, Protein Biosynthesis, Transcriptome, Ribosomes

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b99a867979d27041ab3580d7201cae7Test
https://doi.org/10.1126Test/science.aan2399

المؤلفون: Pamela J. Hicks, George W. Nelson, Martin R. Pollak, Giulio Genovese, Andrea L. Uscinski Knob, Laurence Lecordier, Etienne Pays, Pierrick Uzureau, Barry I. Freedman, David J. Friedman, Donald W. Bowden, Cheryl A. Winkler, Taras K. Oleksyk, Carl D. Langefeld, Andrea J. Bernhardy, Jeffrey B. Kopp, Michael D. Ross, Benoit Vanhollebeke

المصدر: Science. 329:841-845

مصطلحات موضوعية: Trypanosoma brucei rhodesiense, Apolipoprotein L1, Polymorphism, Single Nucleotide, Article, Linkage Disequilibrium, Cohort Studies, Focal segmental glomerulosclerosis, Gene Frequency, medicine, Humans, Genetic Predisposition to Disease, Selection, Genetic, Alleles, Genetic Association Studies, Sequence Deletion, Genetics, Multidisciplinary, Myosin Heavy Chains, biology, Glomerulosclerosis, Focal Segmental, Molecular Motor Proteins, Case-control study, Glomerulosclerosis, Odds ratio, medicine.disease, Immunity, Innate, Recombinant Proteins, Black or African American, Apolipoproteins, Logistic Models, Trypanosomiasis, African, Haplotypes, Case-Control Studies, HIV-associated nephropathy, Africa, Hypertension, Immunology, biology.protein, Kidney Failure, Chronic, Apolipoprotein L, Lipoproteins, HDL, Kidney disease

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49b76cc33ce7ea45d2ca1944301612dfTest
https://doi.org/10.1126Test/science.1193032

المؤلفون: David Stern, Xiaohua C. Huang, Anthony Berno, Stephen P. A. Fodor, Earl Hubbell, Jim Winkler, Macdonald S. Morris, Robert Yang, Mark S. Chee, David J. Lockhart

المصدر: Science. 274:610-614

مصطلحات موضوعية: medicine.medical_specialty, Mitochondrial DNA, Gene Expression, Computational biology, Biology, medicine.disease_cause, DNA, Mitochondrial, Polymerase Chain Reaction, Human mitochondrial genetics, chemistry.chemical_compound, Genetic linkage, Molecular genetics, medicine, Humans, Genetic variability, Cloning, Molecular, Genetics, Base Composition, Mutation, Genome, Polymorphism, Genetic, Multidisciplinary, Base Sequence, Genetic Variation, Nucleic Acid Hybridization, Phycoerythrin, Sequence Analysis, DNA, Fluoresceins, Mitochondria, chemistry, Fluorescein, Oligonucleotide Probes, Molecular probe, Algorithms, DNA

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b05d15c98425bdc8d2e5babf2c4a639fTest
https://doi.org/10.1126Test/science.274.5287.610

المؤلفون: Jeong M. Kim, Jeffrey B. Kopp, Cheryl A. Winkler, Hui Wu, Andrey S. Shaw, Jeffrey H. Miner, Gopa Green, Emil R. Unanue

المصدر: Science. 300:1298-1300

مصطلحات موضوعية: Heterozygote, medicine.medical_specialty, RNA Splicing, Kidney Glomerulus, Immunoglobulins, Antigen-Antibody Complex, Polymerase Chain Reaction, Basement Membrane, Pathogenesis, Mice, Focal segmental glomerulosclerosis, Immune system, Internal medicine, medicine, Animals, Humans, Genetic Predisposition to Disease, Chromatography, High Pressure Liquid, Adaptor Proteins, Signal Transducing, Mice, Knockout, Kidney, Polymorphism, Genetic, Multidisciplinary, biology, Glomerulosclerosis, Focal Segmental, Genetic Variation, Proteins, Epithelial Cells, Glomerulonephritis, Exons, medicine.disease, Endocytosis, Glomerular Mesangium, Cytoskeletal Proteins, Proteinuria, medicine.anatomical_structure, Endocrinology, Ferritins, Mutation, Immunology, biology.protein, Kidney Diseases, Antibody, Haploinsufficiency, Kidney disease

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f81211e636f16c0cf4de34bb0df137b2Test
https://doi.org/10.1126Test/science.1081068

المؤلفون: Hinrich W. H. Göhlmann, Peter Williams, Min Zhu, Didier de Chaffoy, Ennis Lee, Jerome Guillemont, Emmanuelle Cambau, Jean-Marc Neefs, Chantal Truffot-Pernot, Jef Van Gestel, Emma Huitric, Peter Verhasselt, Sven Hoffner, Vincent Jarlier, Philip Timmerman, Koen Andries, Nacer Lounis, Hans Winkler

المصدر: Science

مصطلحات موضوعية: Male, Molecular Sequence Data, Mycobacterium smegmatis, Antitubercular Agents, Drug Evaluation, Preclinical, SQ109, Microbial Sensitivity Tests, Biology, Microbiology, Mycobacterium tuberculosis, Mice, chemistry.chemical_compound, Minimum inhibitory concentration, Drug Resistance, Bacterial, Tuberculosis, Multidrug-Resistant, medicine, Animals, Humans, Point Mutation, Tuberculosis, Amino Acid Sequence, Diarylquinolines, Enzyme Inhibitors, Multidisciplinary, Dose-Response Relationship, Drug, Isoniazid, Pyrazinamide, biology.organism_classification, Protein Subunits, chemistry, Bacterial Proton-Translocating ATPases, Pretomanid, Quinolines, Drug Therapy, Combination, Bedaquiline, Delamanid, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8984ee0a57e605d7184faa01eb0ca800Test
https://hdl.handle.net/10067/514780151162165141Test