The fusarium graminearum genome reveals a link between localized polymorphism and pathogen specialization
| العنوان: | The fusarium graminearum genome reveals a link between localized polymorphism and pathogen specialization |
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| المؤلفون: | David R. Nelson, Hans-Werner Mewes, H. Corby Kistler, Weihong Qi, Kerry O'Donnell, John C. Kennell, Scott E. Baker, Liane R. Gale, Igor V. Tetko, Jon K. Magnuson, Gary J. Muehlbauer, Martin Münsterkötter, Martijn Rep, Karen Hilburn, Jiqiang Yao, B. Gillian Turgeon, Thérèse Ouellet, Hadi Quesneville, Li-Jun Ma, Todd J. Ward, Linda J. Harris, Gerhard Adam, Kim E. Hammond-Kosack, Sarah E. Calvo, Scott Kroken, M. Isabel G. Roncero, Kye Yong Seong, Jin-Rong Xu, Gertrud Mannhaupt, Yueh-Long Chang, Antonio Di Pietro, Ulrich Güldener, Christina A. Cuomo, Evan Mauceli, Rudolf Mitterbauer, John F. Antoniw, Rubella S. Goswami, David DeCaprio, Martin Urban, Cees Waalwijk, Jonathan D. Walton, Sante Gnerre, Frances Trail, Thomas K. Baldwin, Bruce W. Birren |
| المساهمون: | Broad Institute of MIT and Harvard (BROAD INSTITUTE), Harvard Medical School [Boston] (HMS)-Massachusetts Institute of Technology (MIT)-Massachusetts General Hospital [Boston], Technische Universität Munchen - Université Technique de Munich [Munich, Allemagne] (TUM), Institute for Bioinformatics (MIPS), GSF National Research Center for Environment and Health, Purdue University [West Lafayette], Michigan State University [East Lansing], Michigan State University System, Cornell University [New York], Universidad de Córdoba [Cordoba], Pacific Northwest National Laboratory (PNNL), University of Amsterdam [Amsterdam] (UvA), Universität für Bodenkultur Wien [Vienne, Autriche] (BOKU), Rothamsted Research, University of Minnesota [Twin Cities] (UMN), University of Minnesota System, Agriculture and Agri-Food [Ottawa] (AAFC), U.S. Department of Agriculture - Agricultural Research Service - Cereal Disease Laboratory (USDA), USDA-ARS : Agricultural Research Service, Saint Louis University (SLU), University of Arizona, University of Tennessee Memphis, The University of Tennessee Health Science Center [Memphis] (UTHSC), USDA ARS, National Center for Agricultural Utilization Research (USDA ARS,), Institut Jacques Monod (IJM (UMR_7592)), Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Institute of Bioorganic Chemistry and Photochemistry, National Ukrainian Academy of Sciences, Institute Bioorganic Chemistry an Photochemistry, Plant Research International (PRI), Wageningen University and Research [Wageningen] (WUR), Molecular Plant Pathology (SILS, FNWI), Technische Universität München [München] (TUM), Cornell University, University of Minnesota [Twin Cities], Wageningen University and Research Centre [Wageningen] (WUR) |
| المصدر: | Science Science, American Association for the Advancement of Science, 2007, 317 (5843), pp.1400-2. ⟨10.1126/science.1143708⟩ Science, 317(5843), 1400-1402 Science 317 (2007) 5843 Science, 317(5843), 1400-1402. American Association for the Advancement of Science |
| سنة النشر: | 2007 |
| مصطلحات موضوعية: | localized polymorphism, MESH: Sequence Analysis, DNA, neurospora, Sequence analysis, Molecular Sequence Data, Single-nucleotide polymorphism, Genomics, Gene mutation, Biology, dna, medicine.disease_cause, Genome, Polymorphism, Single Nucleotide, Evolution, Molecular, 03 medical and health sciences, MESH: Plant Diseases, Fusarium, MESH: Polymorphism, Genetic, medicine, Point Mutation, DNA, Fungal, Gene, MESH: Evolution, Molecular, 030304 developmental biology, Plant Diseases, MESH: Point Mutation, Genetics, 0303 health sciences, Mutation, MESH: Fusarium, Multidisciplinary, Polymorphism, Genetic, MESH: Molecular Sequence Data, Biointeracties and Plant Health, 030306 microbiology, Point mutation, MESH: Polymorphism, Single Nucleotide, food and beverages, Hordeum, Sequence Analysis, DNA, [SDV.BIBS]Life Sciences [q-bio]/Quantitative Methods [q-bio.QM], MESH: DNA, Fungal, MESH: Hordeum, MESH: Genome, Fungal, Fusarium graminearum genome, PRI Biointeractions en Plantgezondheid, Genome, Fungal, [INFO.INFO-BI]Computer Science [cs]/Bioinformatics [q-bio.QM] |
| الوصف: | We sequenced and annotated the genome of the filamentous fungus Fusarium graminearum , a major pathogen of cultivated cereals. Very few repetitive sequences were detected, and the process of repeat-induced point mutation, in which duplicated sequences are subject to extensive mutation, may partially account for the reduced repeat content and apparent low number of paralogous (ancestrally duplicated) genes. A second strain of F. graminearum contained more than 10,000 single-nucleotide polymorphisms, which were frequently located near telomeres and within other discrete chromosomal segments. Many highly polymorphic regions contained sets of genes implicated in plant-fungus interactions and were unusually divergent, with higher rates of recombination. These regions of genome innovation may result from selection due to interactions of F. graminearum with its plant hosts. |
| وصف الملف: | application/pdf; application/octet-stream |
| اللغة: | English |
| تدمد: | 0036-8075 1095-9203 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c68ac4143eb517beca1ad1b7fc5cb8fTest https://doi.org/10.1126/science.1143708Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....9c68ac4143eb517beca1ad1b7fc5cb8f |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 00368075 10959203 |
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