التفاصيل البيبلوغرافية
| العنوان: |
Native-valve infective endocarditis caused by Enterobacteriaceae: Report on 9 cases and literature review. |
| المؤلفون: |
Aubron, Cecile, Charpentier, Julien, Trouillet, Jean-Louis, Offenstadt, Georges, Mercat, Alain, Bernardin, Gilles, Hyvernat, Herve, Wolff, Michel |
| المصدر: |
Scandinavian Journal of Infectious Diseases; Oct2006, Vol. 38 Issue 10, p873-881, 9p, 2 Charts |
| مصطلحات موضوعية: |
INFECTIVE endocarditis, CARDIAC infections, ENTEROBACTERIACEAE, CRITICAL care medicine, INTENSIVE care units, SALMONELLA |
| مستخلص: |
Although the demographic characteristics of patients who develop infective endocarditis (IE) have changed over the last few decades, Enterobacteriaceae remain rarely responsible. We report the clinical and epidemiological characteristics of 9 patients with native-valve Enterobacteriaceae IE from 6 French medical intensive care units over a 10-y period and have identified 29 additional cases in the literature. Nearly a third of the 38 patients were immunocompromized and/or had previously known valvular heart disease. Salmonella spp. and Yersinia spp. were the most frequently isolated microorganisms reported in the literature. The overall mortality rate was 24% (9/38) and was lower for operated patients (10% (1/10)) compared to those who did not undergo valve surgery (31% (8/26)). Our results confirmed the rarity of native-valve endocarditis caused by Enterobacteriaceae, pathogens frequently responsible for nosocomial and community-acquired bacteraemias. This paradox may be explained by susceptibility to the bactericidal action of serum and the inability of these bacteria to colonize the endocardium. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
