التفاصيل البيبلوغرافية
| العنوان: |
Food allergy—From food avoidance to active treatment. |
| المؤلفون: |
Costa, Célia, Coimbra, Alice, Vítor, Artur, Aguiar, Rita, Ferreira, Ana Luísa, Todo‐Bom, Ana |
| المصدر: |
Scandinavian Journal of Immunology; Jan2020, Vol. 91 Issue 1, pN.PAG-N.PAG, 1p |
| مصطلحات موضوعية: |
FOOD allergy, IMMUNOGLOBULIN E, ALLERGIES, SEROTHERAPY |
| مستخلص: |
The prevalence of food allergy (FA) has increased too rapidly, possibly due to environmental factors. The guidelines recommend strict allergen avoidance, but FA is still the main cause of anaphylaxis in all age groups. Immunotherapy is the only treatment able to change the course of allergic disease, and oral immunotherapy (OIT) is the more effective route in FA. However, it carries the risk of adverse reactions, including anaphylaxis. To improve OIT safety, adjuvant therapy with the immunoglobulin E (IgE) monoclonal antibody omalizumab has been extensively used. Results suggest particular benefit in patients with high risk of fatal anaphylaxis. An alternative approach is to use omalizumab instead of OIT to prevent severe allergic reactions upon accidental exposure. This paper reviews current evidence regarding IgE‐mediated FA, focusing on natural tolerance and food sensitization acquisition, and on avoidance measures and their limitations. [ABSTRACT FROM AUTHOR] |
|
Copyright of Scandinavian Journal of Immunology is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
| قاعدة البيانات: |
Complementary Index |
Full Text Finder