Reversible acral and mucosal hyperpigmentation in a patient with B12 deficiency secondary to polyglandular autoimmune syndrome type II
| العنوان: | Reversible acral and mucosal hyperpigmentation in a patient with B12 deficiency secondary to polyglandular autoimmune syndrome type II |
|---|---|
| المؤلفون: | Meiling Yuen, Rachel Wheatley, Ishan Asokan, Jenna J. Lullo, Jan Smogorzewski |
| المصدر: | SAGE Open Medical Case Reports, Vol 8 (2020) SAGE Open Medical Case Reports |
| بيانات النشر: | SAGE Publishing, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | Autoimmune disease, medicine.medical_specialty, lcsh:R5-920, Syndrome type, business.industry, Cutaneous hyperpigmentation, Case Report, 030209 endocrinology & metabolism, 030206 dentistry, General Medicine, medicine.disease, Hyperpigmentation, Dermatology, 03 medical and health sciences, Malnutrition, 0302 clinical medicine, B12 deficiency, medicine, hyperpigmentation, medicine.symptom, business, lcsh:Medicine (General), polyglandular autoimmune syndrome type II |
| الوصف: | Reversible cutaneous hyperpigmentation often occurs in the setting of nutritional deficiencies and protein energy malnourishment, with atypical presentations arising from autoimmune disease. Here, we present a 52-year-old female with hypertension, type 1 diabetes, and Hashimoto’s thyroiditis, under the diagnosis of polyglandular autoimmune syndrome type II, referred for evaluation of asymptomatic hyperpigmentation of the palms, soles, hard palate, and tongue for 6 months. The patient underwent a significant work-up, including esophagogastroduodenoscopy, which revealed hypertrophic gastropathy as well as evidence of acquired B12 deficiency secondary to pernicious anemia. The patient was initiated on B12 supplementation, with eventual resolution of mucocutaneous findings. |
| اللغة: | English |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c654699ff479e923ea707f2cdd9ca740Test https://doaj.org/article/84679a34cf074274be27b60b222adf43Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....c654699ff479e923ea707f2cdd9ca740 |
| قاعدة البيانات: | OpenAIRE |
| الوصف غير متاح. |