IgA deficiency evidence after anti-TNF-α treatment in a psoriatic arthritis patient: case report
| العنوان: | IgA deficiency evidence after anti-TNF-α treatment in a psoriatic arthritis patient: case report |
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| المؤلفون: | M. Lofrano, M. N. D. Di Minno, Raffaele Scarpa, Salvatore Iervolino, Rosario Peluso, Francesca Foglia |
| المساهمون: | S., Iervolino, M., Lofrano, DI MINNO, Matteo, F., Foglia, R., Scarpa, Peluso, Rosario |
| المصدر: | Reumatismo, Vol 64, Iss 1, Pp 40-43 (2012) |
| بيانات النشر: | PAGEPress Publications, 2012. |
| سنة النشر: | 2012 |
| مصطلحات موضوعية: | psoriatic arthritis, lcsh:Internal medicine, business.industry, Incidence (epidemiology), lcsh:R, lcsh:Medicine, Selective IgA deficiency, medicine.disease, Therapeutic approach, Psoriatic arthritis, Rheumatology, Immunology, medicine, IgA deficiency, Tumor necrosis factor alpha, IgA deficiency, TNF-α blocking therapy, psoriatic arthritis, infective diseases, business, lcsh:RC31-1245, Immunodeficiency, Subclinical infection, TNF-alpha treatment |
| الوصف: | It is known that the use of anti-TNF-α drugs is related to an increased incidence of infective diseases. This therapy can not be administered to patients having active infections and it has to be considered with caution in case of acquired or congenital immunodeficiency diseases. We report the case of a 28-years-old man affected by psoriatic arthritis; he developed some infections during treatment with TNF-α blockers. The infections were caused by a selective IgA deficiency, that was not evident before the anti-TNF-α blockers administration and disappeared after withdrawing the biological therapy. This case-report draws our attention to the possibility of cases of subclinical immunodeficiency, unknown by the patients, but important in the prognosis and in the therapeutic approach to these diseases. Therefore, it is important to evaluate carefully the immunologic status of patients during the pre-therapeutic screening for TNF-α blocking therapy. |
| وصف الملف: | STAMPA |
| اللغة: | English |
| تدمد: | 2240-2683 0048-7449 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dad8e25d9421f940c57c5984bdc81f1Test http://www.reumatismo.org/index.php/reuma/article/view/525Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....9dad8e25d9421f940c57c5984bdc81f1 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 22402683 00487449 |
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