التفاصيل البيبلوغرافية
| العنوان: |
Incremental step test in patients with pulmonary hypertension. |
| المؤلفون: |
Vieira, E.B.1 (AUTHOR), Ota-Arakaki, J.S.1 (AUTHOR) j.ota@unifesp.br, Dal Corso, S.2 (AUTHOR), Ivanaga, I.1 (AUTHOR), Fonseca, A.X.C.1 (AUTHOR), Oliveira, R.K.F.1 (AUTHOR), Rodrigues-Júnior, J.C.2 (AUTHOR), Ferreira, E.V.M.1 (AUTHOR), Nery, L.E.1 (AUTHOR), Ramos, R.P.1 (AUTHOR) |
| المصدر: |
Respiratory Physiology & Neurobiology. Jan2020, Vol. 271, pN.PAG-N.PAG. 1p. |
| مصطلحات موضوعية: |
*PULMONARY hypertension, *EXERCISE tests, *CARDIOPULMONARY system, *REGRESSION analysis, *LINEAR statistical models |
| مستخلص: |
• IST is a useful tool in the clinical evaluation of patients with pre-capillary PH. • The step test demonstrated a greater ability to detect effort-induced desaturation. • Estimated work of IST is associated with V̇O 2 PEAK independently of age and gender. Cardiopulmonary exercise testing (CPET) on a treadmill or cycle ergometer provides an integrated assessment of the cardiorespiratory system during exertion and is widely used in clinical practice. An incremental step test (IST) can be an alternative for eliciting maximal exercise responses. Therefore, 20 patients with pre-capillary PH (65% female, 41 ± 15 yrs) randomly performed a symptom-limited CPET on a cycle ergometer and IST. Metabolic, cardiovascular, ventilatory and gas exchange variables were recorded during both tests. There was a greater desaturation and higher V̇O 2PEAK in IST compared to CPET. The V̇O 2GET, HR PEAK (% pred), Δ V̇ E/ΔV̇CO 2 and ΔHR/ΔV̇O 2 were similar in both IST and CPET. By linear regression analyses, the work performed on IST [W = (mass × 9,8 m/s2 x vertical distance)] was a predictor of peak V̇O 2 independent of the gender and age (r2 = 077, p = 0001). In conclusion, IST elicited higher peak cardiopulmonary responses and has a good agreement with known severity markers in patients with pre-capillary PH. [ABSTRACT FROM AUTHOR] |
| قاعدة البيانات: |
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