Integrated Use of Lung Ultrasound and Chest X-Ray in the Detection of Interstitial Lung Disease
| العنوان: | Integrated Use of Lung Ultrasound and Chest X-Ray in the Detection of Interstitial Lung Disease |
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| المؤلفون: | Paola Forti, Luca Vizioli, Marco Zoli, Marco Giovagnoli, Anna Maria Chiesa, Federica Ciccarese, Martina Mughetti, Maurizio Zompatori |
| المساهمون: | Vizioli, L., Ciccarese, F., Forti, P., Chiesa, A.M., Giovagnoli, M., Mughetti, M., Zompatori, M., Zoli, M. |
| المصدر: | Respiration. 93:15-22 |
| بيانات النشر: | S. Karger AG, 2016. |
| سنة النشر: | 2016 |
| مصطلحات موضوعية: | Male, Pulmonary and Respiratory Medicine, Chest ultrasound, medicine.medical_specialty, Radiography, Combined use, behavioral disciplines and activities, Sensitivity and Specificity, 03 medical and health sciences, 0302 clinical medicine, X ray computed, medicine, Humans, Prospective cohort study, Aged, Ultrasonography, interstitial lung disease, 030203 arthritis & rheumatology, Lung ultrasound, business.industry, Interstitial lung disease, Gold standard (test), Middle Aged, respiratory system, medicine.disease, respiratory tract diseases, 030228 respiratory system, Female, Radiography, Thoracic, Radiology, Lung Diseases, Interstitial, Tomography, X-Ray Computed, business |
| الوصف: | Background: Current data have shown that lung ultrasound (LUS) may be useful in the detection of interstitial lung disease (ILD) by the evaluation of B-lines, the sonographic marker of pulmonary interstitial syndrome. Nevertheless, no prospective study has compared LUS to chest X-ray (CXR) for ILD assessment, and there is no general agreement on the specific echographic diagnostic criteria for defining ILD. Objectives: The aims of this study were (1) to compare the accuracy of LUS and CXR in the detection of ILD using high-resolution CT (HRCT) as the gold standard and (2) to compare the accuracy of different echographic diagnostic criteria for ILD diagnosis. Methods: LUS was performed on 104 patients undergoing HRCT for suspected ILD. In 49 patients, a CXR scan performed within 3 months of HRCT was analyzed. ILD was defined as the presence of ≥5 B-lines in ≥3 chest areas. A total B-line score (TBLS) was also calculated, as in previous studies. The observers evaluating LUS and CXR were blinded to the HRCT results and clinical data. Results: On HRCT, ILD was assessed in 50 patients. CXR was specific (91%; 95% CI 80-100) but not sensitive (48%; 95% CI 28-67). Conversely, LUS showed high sensitivity (92%; 95% CI 84-99) and low specificity (79%; 95% CI 69-90). Using a TBLS, sensitivity did not change, while specificity decreased. Conclusions: LUS could be a sensitive tool for ILD detection. CXR and LUS have different but complementary features, and their combined use could reduce the need for HRCT. The use of different diagnostic criteria for defining ILD does not affect sensitivity but influences specificity. |
| وصف الملف: | STAMPA |
| تدمد: | 1423-0356 0025-7931 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ebbc0d9a420457cdd5a51ebf2a90e57Test https://doi.org/10.1159/000452225Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....5ebbc0d9a420457cdd5a51ebf2a90e57 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14230356 00257931 |
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