التفاصيل البيبلوغرافية
| العنوان: |
Exposure to endocrine disrupting chemicals (bisphenols, parabens, and triclosan) and their associations with preterm birth in humans. |
| المؤلفون: |
Kek, Tina1 (AUTHOR) tina.kek@kclj.si, Geršak, Ksenija2,3 (AUTHOR), Virant-Klun, Irma1 (AUTHOR) |
| المصدر: |
Reproductive Toxicology. Apr2024, Vol. 125, pN.PAG-N.PAG. 1p. |
| مصطلحات موضوعية: |
*ENDOCRINE disruptors, *CHILDBIRTH, *BISPHENOLS, *TRICLOSAN, *MEDICAL personnel, *PREMATURE labor, *NEONATAL death |
| مستخلص: |
Preterm birth in humans (PTB), defined as birth prior to 37 weeks of gestation, is one of the most important causes of neonatal morbidity and mortality and is associated with adverse health outcomes later in life. Attributed to many different etiological factors, estimated 15.1 million or 11.1% of births each year are preterm, which is more than 1 per 10 livebirths globally. Environmental pollution is a well-established risk factor that could influence the pathogenesis of PTB. Increasing evidence has shown an association between maternal exposure to endocrine disrupting chemicals (EDCs) and PTB. This scoping review aims to summarize current research on the association between EDC exposure and PTB in humans. Database PubMed was used to identify articles discussing the effect of selected EDCs, namely bisphenol A, bisphenol S, bisphenol F, parabens, and triclosan, found in plastics, cosmetics and other personal care products, on PTB occurrence. Regardless of some inconsistences in the findings across studies, the reviewed studies suggest a potential association between involuntary exposure to reviewed EDCs and the risk of PTB. However, further studies are needed to delineate exact correlations and mechanisms through which EDC exposure causes PTB so that efficient preventative measures could be implemented. Until then, health care providers should inform women about possible EDC exposure thus empowering them to make healthy choices and at the same time decrease the EDC negative effects. • Environmental pollution is a one of the risk factors for preterm birth (PTB). • Scoping review evaluating endocrine disruptors' effect on PTB in humans. • Potential link is suggested between bisphenols, parabens, triclosan and PTB risk. • Proposed effects are endocrine, immune disruption, oxidative stress, and epigenetics. • Further studies are needed to delineate exact correlations and mechanisms. [ABSTRACT FROM AUTHOR] |
| قاعدة البيانات: |
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