يعرض 1 - 9 نتائج من 9 نتيجة بحث عن '"Hypoxia-inducible factor-1?"', وقت الاستعلام: 0.94s تنقيح النتائج
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    المصدر: Redox Biology, Vol 13, Iss C, Pp 426-443 (2017)
    Redox Biology

    مصطلحات موضوعية: 0301 basic medicine, CM-H2DCFDA, 2′,7′-dichlorodihydrofluorescein diacetate, FFA, Free fatty acid, FASN, fatty acid synthase, Clinical Biochemistry, PBA, 4-phenyl butyric acid, Apoptosis, Biochemistry, Mice, MAGL, monoacylglycerol lipase, DGAT1, diglyceride acyltransferase 1, Mitophagy, CHOP, CCAAT-enhancer binding protein homologous protein, Fatty acid synthase (FASN), FOXO3, forkhead box, class O3, S.E.M, standard error of mean, Cyclic AMP Response Element-Binding Protein, Hypoxia, lcsh:QH301-705.5, CPT1A, carnitine palmitoyltransferase 1A, Caspase, NAC, N-acetyl-L-cysteine, Mesenchymal stem cell, lcsh:R5-920, UCB-hMSCs, umbilical cord blood-derived hMSCs, HNA, human nuclear antigen, biology, GPAT1, glycerol-3-phsphate acyltransferase 1, TMRE, tetramethylrhodamine ethyl ester, Fatty Acids, Forkhead Box Protein O3, BNIP3, Bcl2/adenovirus E1B 19 kDa protein-interacting protein 3, HIF-1α, hypoxia-inducible factor-1 alpha, Cell Hypoxia, Mitochondria, Cell biology, Fatty Acid Synthase, Type I, Fatty acid synthase, HMSCs, human mesenchymal stem cells, Bcl2/adenovirus E1B 19 kDa protein-interacting protein 3 (BNIP3), FOXO3, FITC, fluorescein isothiocyanate, Stem cell, medicine.symptom, Sterol Regulatory Element Binding Protein 1, lcsh:Medicine (General), Research Paper, eIF-2α, eukaryotic initiation factor 2 alpha, PBS, phosphate buffered solution, Mesenchymal Stem Cell Transplantation, Cell Line, PI, propidium iodide, PA, palmitic acid, 03 medical and health sciences, ROS, reactive oxygen species, TBST, tris-buffered saline containing 0.1% Tween-20, mtROS, mitochondrial ROS, Proto-Oncogene Proteins, CCCP, carbonyl cyanide m-chlorophenyl hydrazine, CHIP, chromatin immunoprecipitation, medicine, Animals, Humans, SCD1, stearoyl-CoA desaturase 1, CBP, CREB-binding protein, SREBP1, sterol regulatory element binding protein 1, Wound Healing, FA, fatty acid, FUNDC1, FUN14 domain containing 1, Organic Chemistry, Membrane Proteins, Mesenchymal Stem Cells, Lipid metabolism, Annexin V, FITC-conjugated annexinV, PINK1, PTEN-induced putative kinase1, Hypoxia (medical), Hypoxia-Inducible Factor 1, alpha Subunit, Molecular biology, BCA, bicinchoninic acid, NT, non-targeting, Oxygen, 030104 developmental biology, lcsh:Biology (General), biology.protein, Reactive Oxygen Species

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    المصدر: Redox Biology
    Redox Biology, Vol 13, Iss C, Pp 20-31 (2017)

    مصطلحات موضوعية: 0301 basic medicine, MAPK/ERK pathway, Pathology, Clinical Biochemistry, STAT5, signal transducer and activator of transcription 5, Cell Communication, Biochemistry, chemistry.chemical_compound, Phosphatidylinositol 3-Kinases, 0302 clinical medicine, ERK, extracellular signal-regulated kinase, Bi-directional communication, STAT5 Transcription Factor, lcsh:QH301-705.5, STAT5, Cells, Cultured, IP, ischmia-preconditionning, Neurons, lcsh:R5-920, TUNEL assay, Mitogen-Activated Protein Kinase 3, PI3K, phosphatidylinositol 3-kinase, Glutathione, Cell Hypoxia, Cell biology, JAK-2, Janus kinase-2, medicine.anatomical_structure, rhEPO, recombinant human EPO, IPcNCM, ischemia-preconditioned neuron culture medium, KA, kainic acid, lcsh:Medicine (General), Astrocyte, Research Paper, Cell signaling, medicine.medical_specialty, Kainic acid, MTT, 3-(4,5-dimethylthazol-2-yl)-2,5-diphenyltetrazolinum bromide, Astro-protection, Ischemia, GFAP, glial fibrillary acadic protein, DNA Fragmentation, Biology, CNS, central nervous system, 03 medical and health sciences, MAP2, microtubule-associated protein 2, In vivo, medicine, Animals, L-Lactate Dehydrogenase, Organic Chemistry, medicine.disease, OGD, oxygen glucose deprivation, Rats, Oxygen, 030104 developmental biology, chemistry, lcsh:Biology (General), Astrocytes, HIF-1alpha, hypoxia-inducible factor-1 alpha, biology.protein, EPO, erythropoietin, Reactive Oxygen Species, 030217 neurology & neurosurgery, Anti-apoptosis and anti-oxidant

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    المصدر: Redox Biology, Vol 8, Iss C, Pp 175-185 (2016)
    Redox Biology

    مصطلحات موضوعية: 0301 basic medicine, Male, MM, Multiple myeloma, Thioredoxin reductase, Clinical Biochemistry, PBMCs, Peripheral blood mononuclear cells, Apoptosis, ARE, Antioxidant response element, Pharmacology, Biochemistry, Antioxidants, Bortezomib, 0302 clinical medicine, Multiple myeloma, hemic and lymphatic diseases, Nrf2, Nuclear factor-E2-related factor 2, HIF-1β, Hypoxia inducible factor-1 beta, Molecular Targeted Therapy, Enzyme Inhibitors, lcsh:QH301-705.5, BM, Bone marrow, lcsh:R5-920, CLL, Chronic lymphocytic leukemia, Trx, Thioredoxin, Middle Aged, Gene Expression Regulation, Neoplastic, medicine.anatomical_structure, ZnPP IX, Zinc Protoporphyrin IX, Heme oxygenase-1, 030220 oncology & carcinogenesis, Female, Thioredoxin, ANOVA, Analysis of variance, HO-1, Heme oxygenase-1, lcsh:Medicine (General), Oxidation-Reduction, Chemoresistance, medicine.drug, Protein Binding, Signal Transduction, Research Paper, Auranofin, Thioredoxin-Disulfide Reductase, NF-E2-Related Factor 2, Antineoplastic Agents, AP-1, Activator protein-1, AF, Auranofin, 03 medical and health sciences, CuPP IX, Copper Protoporphyrin IX, Cell Line, Tumor, medicine, NF-кβ, Nuclear factor kappa beta, Humans, TrxR, Thioredoxin reductase, business.industry, CML, Chronic myeloid leukemia, Organic Chemistry, Btz, Bortezomib, medicine.disease, Heme oxygenase, Enzyme Activation, 030104 developmental biology, lcsh:Biology (General), Drug Resistance, Neoplasm, AML, Acute myeloid leukemia, Bone marrow, business, Reactive Oxygen Species, ROS, Reactive oxygen species

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    المصدر: Redox Biology
    Redox Biology, Vol 25, Iss, Pp-(2019)

    مصطلحات موضوعية: 0301 basic medicine, Liver Cirrhosis, Male, CTAD, C-terminal activation domain, HO-1, heme Oxygenase-1, PARP, cleaved poly (ADP-ribose) polymerase, TFAM, transcription factor A, mitochondrial, Transcription, Genetic, MT-COII, mitochondrial-encoded cytochrome c oxidase II, Clinical Biochemistry, GAPDH, glyceraldehyde 3-phosphate dehydrogenase, TMRM, tetramethylrhodamine methyl ester, MT-CYB, mitochondrial-encoded cytochrome b, HDAC, histone deacetylase, Apoptosis, Mitochondrion, medicine.disease_cause, Biochemistry, HIF-1, hypoxia inducible factor-1, TIMM17A, translocase of inner mitochondrial membrane 17A, Mice, 0302 clinical medicine, HUVEC, human umbilical vein endothelial cell, lcsh:QH301-705.5, GSH, Glutathione, chemistry.chemical_classification, Regulation of gene expression, NFE2L2, Nuclear factor erythroid 2-related factor 2, Membrane Potential, Mitochondrial, lcsh:R5-920, education.field_of_study, ID, inhibitory domain, ROS, Cell Hypoxia, Cell biology, Mitochondria, Protein Transport, lcsh:Medicine (General), Population, PCNA, proliferating cell nuclear antigen, HIF-1α, Down-Regulation, DNA, Mitochondrial, Article, Cell Line, 03 medical and health sciences, ROS, reactive oxygen species, medicine, Animals, Humans, RNA, Messenger, TOMM40, translocase of outer mitochondrial membrane 40, education, Transcription factor, PHD, prolyl hydroxylases, SOD2, superoxide dismutase 2, Reactive oxygen species, Organic Chemistry, WCL, whole cell lysates, Hydrogen Peroxide, Subcellular localization, Hypoxia-Inducible Factor 1, alpha Subunit, mtDNA, mitochondrial DNA, AIF, apoptosis-inducing factor, Mice, Inbred C57BL, Oxidative Stress, 030104 developmental biology, NTAD, N-terminal activation domain, lcsh:Biology (General), chemistry, Cytoprotection, DMOG, dimethyloxaloylglycine, MT-ND1, mitochondrial-encoded NADH dehydrogenase I, nDNA, nuclear DNA, ΔΨm, Mitochondrial membrane potential, CAT, catalase, 030217 neurology & neurosurgery, Oxidative stress, HA, hemagglutinin

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    المصدر: Redox Biology, Vol 4, Iss C, Pp 184-192 (2015)
    Redox Biology

    مصطلحات موضوعية: ATG8, autophagy related gene 8, Clinical Biochemistry, Autophagy-Related Proteins, mTORC1, mammalian target of rapamycin complex, Tumor initiation, AMP-Activated Protein Kinases, Biochemistry, Metastasis, Neoplasms, Tumor Microenvironment, Autophagy-Related Protein-1 Homolog, SQSTM1, sequestosome 1, HMGB1, high-mobility group protein B 1, lcsh:QH301-705.5, Cancer, lcsh:R5-920, Kelch-Like ECH-Associated Protein 1, GABARAPL2, GABARAP protein-like 2, Intracellular Signaling Peptides and Proteins, Mitophagy, ROS, Primary tumor, Mitochondria, Cell biology, NLRP3, NOD-like receptor family, pyrin domain containing 3, Gene Expression Regulation, Neoplastic, PINK1, PTEN induced putative kinase 1, Cysteine Endopeptidases, Cell Transformation, Neoplastic, Lymphatic Metastasis, NRF2, nuclear factor erythroid 2-related factor 2, KEAP1, Kelch-like ECH-associated protein 1, HSP, heat shock protein, Beclin-1, Antioxidant, EMT, epithelial-mesenchymal transition, lcsh:Medicine (General), Signal Transduction, Mini Review, ATG, autophagy related gene, Antineoplastic Agents, Protein Serine-Threonine Kinases, Biology, HIF-1α, hypoxia-inducible factor-1 α, ROS, reactive oxygen species, Cancer stem cell, Autophagy, medicine, Humans, GEC1, glandular epithelial cell 1, Tumor microenvironment, Organic Chemistry, Membrane Proteins, medicine.disease, LC3, light chain 3, ULK1, unc-51 like autophagy activating kinase 1, AMPK, AMP-activated protein kinase, GABARAPL1, GABARAP protein-like 1, lcsh:Biology (General), Cancer cell, BNIP3, BCL-2/adenovirus E1B 19-kDa-interacting protein 3, Apoptosis Regulatory Proteins, Reactive Oxygen Species, 3-MA, 3-methyladenine, GABARAP, GABAA receptor-associated protein

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    المصدر: Redox Biology, Vol 2, Iss C, Pp 400-410 (2014)
    Redox Biology

    مصطلحات موضوعية: HIF-1α, hypoxia inducible factor-1, TF, transcription factor, Radioprotection, Redox-modulators, Clinical Biochemistry, SP-1, specificity protein-1, Pharmacology, Mitochondrion, Infusions, Subcutaneous, medicine.disease_cause, Breathing frequencies, Biochemistry, CO3−, carbonate radical, I/R, ischemia reperfusion, chemistry.chemical_compound, ETC, mitochondrial electron transport chain, GMP, good manufacturing practice, AT, ataxia telangiectasia, ALS, amyotrophic laterial sclerosis, 8-OHdG, 8-hydroxy-2'-deoxyguanosine, Lung, lcsh:QH301-705.5, PI3K, phosphatidylinositide 3-kinase, lcsh:R5-920, O2−, superoxide, Nrf-2, nuclear factor-erythroid-derived 2-like 2, MnTnHex-2-PyP5+, VEGF, vascular endothelial growth factor, Lung injury, Immunohistochemistry, 3. Good health, BBB, blood brain barrier, medicine.anatomical_structure, Toxicity, Female, NF-κB, nuclear factor κB, lcsh:Medicine (General), Oxidation-Reduction, AP-1, activator protein-1, Signal Transduction, medicine.medical_specialty, MnTE-2-PyP5+, Mn(III) meso-tetrakis(N-ethylpyridinium-2-yl)porphyrin (AEOL10113), Metalloporphyrins, HO2−, monodeprotonated hydrogen peroxide, mTOR, mammalian target of rapamycin (mTOR), a serine/threonine protein kinase, Histopathology, Radiation-Protective Agents, CNS, central nervous system, Drug Administration Schedule, Article, NOX4, NADPH oxidase, isoform 4 E1/2, Half-wave metal-centered reduction potential, MnTDE-2-ImP5+, Mn(III) tetrakis[N,N'-diethylimidazolium-2-yl)porphyrin, AEOL10150, GS−, monodeprotonated glutathione, SOD, superoxide dismutase, MnTnBuOE-2-PyP5+, Mn(III) meso-tetrakis(N-(n-butoxyethyl)pyridinium-2-yl)porphyrin, medicine, Animals, MCAO, middle cerebral artery occlusion, NO, nitric oxide, ClO−, hypochlorite, PTEN, phosphoinositide 3-phosphatase, Body Weight, Organic Chemistry, Dose-Response Relationship, Radiation, AKT, protein kinase B (PKB), a serine/threonine-specific protein kinase, ONOO−, peroxynitrite, MnTnHex-2-PyP5+, Mn(III) meso-tetrakis(N-(n-hexyl)pyridinium-2-yl)porphyrin (AEOL10113), Porphyrin, Fischer rats, Rats, Inbred F344, Rats, Staining, Manganese porphyrins, chemistry, lcsh:Biology (General), MnP, Mn porphyrin, MnTE-2-PyP5+, NHE, normal hydrogen electrode, TGF-β1, one of the 3 members of the TGF-β transforming growth factor-β family, SAH, subarachnoid hemorrhage, Oxidative stress

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    المصدر: Redox Biology
    Redox Biology, Vol 1, Iss 1, Pp 258-264 (2013)

    مصطلحات موضوعية: Fe/S, iron/SULFUR, ERAD, endoplasmic reticulum-associated degradation, Aging, WI-38, human lung fibroblast, Protease La, Clinical Biochemistry, Respiratory chain, Adaptation, Biological, Cellular homeostasis, 2D-PAGE, two-dimensional polyacrylamide gel electrophoresis, AAA, ATPases associated with diverse cellular activities, Review Article, Mitochondrion, medicine.disease_cause, MPPβ, mitochondrial processing peptidase beta subunit, Biochemistry, HIF-1, hypoxia inducible factor-1, CDDO-Me, methyl-2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oate, Prx1, mitochondrial peroxiredoxin 1, SLLVY-AMC, N-succinyl-Leu-Leu-Val-Tyr-7-amino-4-methylcoumarin, Chronic stress, Disease, lcsh:QH301-705.5, SOD2, mitochondrial superoxide dismutase 2, lcsh:R5-920, HsIVU, bacterial ATP-dependent protease, Aco1, Aconitase 1, Mitochondria, Up-Regulation, COX, cytochrome c oxidase, COX4-1, cytochrome c oxidase subunit IV isoform 1, HSP60, HSP60, heat shock protein 60, lcsh:Medicine (General), PRSS15, LON gene, Senescence, Pim1, ATP-dependent Lon protease from yeast, SOD2, Biology, SOD, cytosolic superoxide dismutase, Ccp1, mitochondrial cytochrome-c peroxidase, FRDA, Friedreich's ataxia, Hormesis, NRF-2, nuclear factor (erythroid-derived 2)-like 2, MELAS, mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes, medicine, Clp, caseinolytic protease, Animals, Humans, SPG13, hereditary spastic paraplegia, Protease La, ATP-dependent protease, Yjl200c, mitochondrial aconitase isozyme, Adaptation, COX4-2, cytochrome c oxidase subunit IV isoform 2, Organic Chemistry, Lon Protease, Nfκb, nuclear factor kappa-light-chain-enhancer of activated B csells, HAART, highly active antiretroviral therapy, CDDO, 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid, Oxidative Stress, lcsh:Biology (General), bacteria, HSP104, heat shock protein 104, ClpP, core catalytic protease unit, Oxidative stress, Protein degradation and oxidation

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    المصدر: Redox Biology
    Redox Biology, Vol 1, Iss 1, Pp 599-607 (2013)

    مصطلحات موضوعية: Male, Pathology, HIF-1α, hypoxia inducible factor-1, TF, transcription factor, Radiation proctitis, Proton beam therapy, medicine.medical_treatment, Clinical Biochemistry, SP-1, specificity protein-1, Biochemistry, Rats, Sprague-Dawley, Prostate, Biomimetic Materials, GSH, glutathione, CGE, cobalt gray equivalent, lcsh:QH301-705.5, lcsh:R5-920, MnTE-2-PyP5+, Mn(III) meso-tetrakis(N-ethylpyridinium-2-yl)porphyrin (AEOL10113, BMX-010), biology, Mn porphyrin, medicine.anatomical_structure, NF-κB, nuclear factor κB, lcsh:Medicine (General), AP-1, activator protein-1, Research Paper, medicine.medical_specialty, kcat(O2−), the rate constant for the catalysis of O2− dismutation by Mn porphyrin or SOD enzyme, Metalloporphyrins, Injections, Subcutaneous, Radioprotector, Urology, Rectum, Radiation-Protective Agents, MnTnBuOE-2-PyP5+, Mn(III) meso-tetrakis(N-n-butoxyethylpyridinium-2-yl)porphyrin, Superoxide dismutase, SOD, superoxide dismutase, medicine, Animals, Proctitis, PT, proton therapy, Adverse effect, SOD mimic, Dose-Response Relationship, Drug, business.industry, Organic Chemistry, Cancer, medicine.disease, MnP, Mn(III) porphyrins, MnTM-2-PyP5+, Mn(III) meso-tetrakis(N-methylpyridinium-2-yl)porphyrin (AEOL10112), Rats, MnTDE-2-ImP5+, Mn(III) meso-tetrakis(N,N’-diethylimidazolium-2-yl)porphyrin (AEOL10150), Radiation therapy, lcsh:Biology (General), MnTnHex-2-PyP5+, Mn(III) meso-tetrakis(N-n-hexylpyridinium-2-yl)porphyrin (BMX-001), biology.protein, MnTE-2-PyP5+, business