المصدر: Reactions Weekly. 6/22/2024, Vol. 2013 Issue 1, p306-306. 1p.

مصطلحات موضوعية: *OFF-label use (Drugs), *NAUSEA, *DRUGS

مستخلص: A 17-year-old girl experienced nausea and lack of efficacy following off-label treatments for myelin oligodendrocyte glycoprotein-immunoglobulin G-associated disease (MOGAD). She initially received azathioprine, but developed nausea and had to discontinue the treatment. She then tried tacrolimus and mycophenolate mofetil, but both showed lack of efficacy. Eventually, she found success with plasmapheresis and double filtration plasmapheresis, along with IV methylprednisolone and oral prednisolone. However, she experienced relapses and had to discontinue various treatments due to side effects or lack of efficacy. She eventually found success with SC ofatumumab and discontinued prednisolone. [Extracted from the article]

المصدر: Reactions Weekly. May2024, Vol. 2006 Issue 1, p74-74. 1p.

مصطلحات موضوعية: *ANTINEOPLASTIC agents, *NAUSEA, *APPETITE, *COLON cancer, *LITERATURE reviews, *APPETITE stimulants

مستخلص: A 34-year-old man with colon cancer experienced lack of efficacy and gastrointestinal side effects during his treatment with various antineoplastic drugs. Initially, he underwent surgery and received platinum-based adjuvant chemotherapy, but his cancer metastasized and recurred. He then underwent surgery again and was switched to a different treatment regimen, which caused nausea, poor appetite, hyperthyroidism, and impaired liver function. Despite these side effects, he achieved complete remission and was still being followed up at the time of the report. [Extracted from the article]

المصدر: Reactions Weekly. Apr2024, Vol. 2005 Issue 1, p20-20. 1p.

مصطلحات موضوعية: *NAUSEA

مستخلص: A case series of five patients with KRASG12C-mutated non-small cell lung cancer (NSCLC) who were treated with adagrasib was described. The patients experienced either nausea or lack of efficacy during the treatment. The patients had varying responses to the treatment, with some experiencing stable disease and others showing disease progression. Adagrasib dosages were adjusted for some patients, and in some cases, the treatment was discontinued due to lack of efficacy. [Extracted from the article]

المصدر: Reactions Weekly. 3/30/2024, Vol. 2001 Issue 1, p262-262. 1p.

مصطلحات موضوعية: *NAUSEA, *DRUGS, *CHRONIC hepatitis B, *SUMATRIPTAN

مستخلص: A 30-year-old woman experienced gastrointestinal side effects and nausea while being treated for generalized plaque psoriasis and chronic hepatitis B infection. She also did not respond well to several medications for her psoriasis and misused some of them. Despite trying different treatments, her symptoms persisted until she was diagnosed with chronic hepatitis B and started taking tenofovir, which significantly improved her psoriasis. However, she eventually discontinued tenofovir due to nausea. [Extracted from the article]

المصدر: Reactions Weekly. 2/17/2024, Vol. 1995 Issue 1, p91-91. 1p.

مصطلحات موضوعية: *MENINGITIS, *NAUSEA, *SUMATRIPTAN, *CEREBROSPINAL fluid examination

مستخلص: In a retrospective study conducted between 2017 and 2022, 12 patients with pediatric acute-onset neuropsychiatric syndrome (PANS) were treated with immune-globulin. One male patient developed aseptic meningitis, while another patient experienced nausea as a result of the treatment. The patient with aseptic meningitis was diagnosed with immune-globulin induced aseptic meningitis, leading to the discontinuation of immune-globulin in that patient. The study does not provide information on the ages or sexes of the patients, dosages, time to reaction onset, or outcomes. [Extracted from the article]

المصدر: Reactions Weekly. 2/17/2024, Vol. 1995 Issue 1, p75-75. 1p.

مصطلحات موضوعية: *NAUSEA, *DEHYDRATION, *RETROPERITONEUM diseases, *IFOSFAMIDE, *FATIGUE (Physiology), *EXERCISE tolerance

مستخلص: A man in his 40s experienced nausea and dehydration while undergoing treatment for dedifferentiated liposarcoma with doxorubicin and ifosfamide. Prior to this, he had complained of various symptoms and was diagnosed with dedifferentiated liposarcoma. He underwent portal vein embolisation and hepatic vein embolisation, which resulted in liver hypertrophy. After starting chemotherapy, he developed chemotherapy-related nausea and dehydration and was admitted to the hospital. He received fluid therapy and antiemetic treatment, and his subsequent scans showed stable tumor size and liver hypertrophy. [Extracted from the article]

المصدر: Reactions Weekly. 1/27/2024, Vol. 1992 Issue 1, p102-102. 1p.

مصطلحات موضوعية: *NAUSEA, *DIZZINESS, *SUMATRIPTAN

مستخلص: Author InformationAn event is serious (based on the ICH definition) when the patient outcome is:• * death * life-threatening * hospitalisation * disability * congenital anomaly * other medically important eventIn a retrospectively and prospective study, conducted between 16 November 2009 to 22 January 2010, in Taiwan, involving 9115 patients, et al. patient [age and sex not stated] was described, who developed dizziness, nausea and weakness following immunisation with influenza-A-virus-vaccine-H1N1. [Extracted from the article]

المصدر: Reactions Weekly. 11/25/2023, Vol. 1984 Issue 1, p123-123. 1p.

مصطلحات موضوعية: *SPINAL injections, *NAUSEA, *VOMITING, *DRUGS, *MORNING sickness, *BUPIVACAINE

مستخلص: In a case report published in Reactions Weekly, a study involving 70 adult women found that one woman experienced nausea and vomiting after receiving bupivacaine as anesthesia during delivery. The woman, whose exact age was not stated, had a singleton pregnancy and underwent a lower segment caesarian section. She received prophylactic treatment for hypotension and a spinal injection of bupivacaine. The nausea and vomiting were attributed to the bupivacaine. [Extracted from the article]

المصدر: Reactions Weekly. Nov2023, Vol. 1982 Issue 1, p101-101. 1p.

مصطلحات موضوعية: *CABERGOLINE, *NAUSEA, *VOMITING, *MENSTRUAL cycle, *BROMOCRIPTINE

مستخلص: A 28-year-old woman experienced nausea and vomiting while being treated with oral cabergoline for macroprolactinoma. She also did not respond well to intra-vaginal cabergoline treatment for the same condition. After discontinuing cabergoline, she was switched to bromocriptine, which partially helped but was discontinued due to supply issues. She underwent transsphenoidal surgery and experienced regular menstrual cycles and no more galactorrhea. However, her serum prolactin levels remained high and her tumor volume slightly increased while being treated with intra-vaginal cabergoline, indicating a lack of efficacy. Cabergoline treatment was subsequently stopped. [Extracted from the article]

المصدر: Reactions Weekly. Nov2023, Vol. 1981 Issue 1, p172-172. 1p.

مصطلحات موضوعية: *HEADACHE, *NAUSEA, *SUMATRIPTAN