دورية أكاديمية
Clinical features and outcomes of COVID-19 patients hospitalized for psychiatric disorders: a French multi-centered prospective observational study
| العنوان: | Clinical features and outcomes of COVID-19 patients hospitalized for psychiatric disorders: a French multi-centered prospective observational study |
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| المؤلفون: | Dobre, Daniela, Schwan, Raymund, Jansen, Claire, Schwitzer, Thomas, Martin, Olivier, Ligier, Fabienne, Rolland, Benjamin, Ahad, Pierre Abdel, Capdevielle, Delphine, Corruble, Emmanuelle, Delamillieure, Pascal, Dollfus, Sonia, Drapier, Dominique, Bennabi, Djamila, Joubert, Fabien, Lecoeur, William, Massoubre, Catherine, Pelissolo, Antoine, Roser, Mathilde, Schmitt, Christophe, Teboul, Noé, Vansteene, Clément, Yekhlef, Wanda, Yrondi, Antoine, Haoui, Radoine, Gaillard, Raphaël, Leboyer, Marion, Thomas, Pierre, Gorwood, Philip, Laprevote, Vincent |
| المصدر: | Psychological Medicine ; page 1-9 ; ISSN 0033-2917 1469-8978 |
| بيانات النشر: | Cambridge University Press (CUP) |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Psychiatry and Mental health, Applied Psychology |
| الوصف: | Background Patients with psychiatric disorders are exposed to high risk of COVID-19 and increased mortality. In this study, we set out to assess the clinical features and outcomes of patients with current psychiatric disorders exposed to COVID-19. Methods This multi-center prospective study was conducted in 22 psychiatric wards dedicated to COVID-19 inpatients between 28 February and 30 May 2020. The main outcomes were the number of patients transferred to somatic care units, the number of deaths, and the number of patients developing a confusional state. The risk factors of confusional state and transfer to somatic care units were assessed by a multivariate logistic model. The risk of death was analyzed by a univariate analysis. Results In total, 350 patients were included in the study. Overall, 24 (7%) were transferred to medicine units, 7 (2%) died, and 51 (15%) patients presented a confusional state. Severe respiratory symptoms predicted the transfer to a medicine unit [odds ratio (OR) 17.1; confidence interval (CI) 4.9–59.3]. Older age, an organic mental disorder, a confusional state, and severe respiratory symptoms predicted mortality in univariate analysis. Age >55 (OR 4.9; CI 2.1–11.4), an affective disorder (OR 4.1; CI 1.6–10.9), and severe respiratory symptoms (OR 4.6; CI 2.2–9.7) predicted a higher risk, whereas smoking (OR 0.3; CI 0.1–0.9) predicted a lower risk of a confusional state. Conclusion COVID-19 patients with severe psychiatric disorders have multiple somatic comorbidities and have a risk of developing a confusional state. These data underline the need for extreme caution given the risks of COVID-19 in patients hospitalized for psychiatric disorders. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.1017/s0033291721001537 |
| الإتاحة: | https://doi.org/10.1017/s0033291721001537Test https://www.cambridge.org/core/services/aop-cambridge-core/content/view/S0033291721001537Test |
| حقوق: | http://creativecommons.org/licenses/by/4.0Test/ |
| رقم الانضمام: | edsbas.1164166E |
| قاعدة البيانات: | BASE |
| DOI: | 10.1017/s0033291721001537 |
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