التفاصيل البيبلوغرافية
| العنوان: |
Morbidity of curative cancer surgery and suicide risk. |
| المؤلفون: |
Jayakrishnan, Thejus T., Sekigami, Yurie, Rajeev, Rahul, Gamblin, T. Clark, Turaga, Kiran K. |
| المصدر: |
Psycho-Oncology; Nov2017, Vol. 26 Issue 11, p1792-1798, 7p, 3 Charts, 1 Graph |
| مصطلحات موضوعية: |
ONCOLOGIC surgery, DISEASE risk factors, SUICIDE risk factors, CANCER patient psychology, PALLIATIVE treatment, SUICIDE & psychology, TUMOR surgery, TUMORS & psychology, AGE distribution, DATABASES, DISEASES, MULTIVARIATE analysis, PROGNOSIS, PUBLIC health surveillance, SEX distribution, SUICIDE, TIME, TUMORS, DISEASE incidence, RETROSPECTIVE studies |
| مستخلص: |
Importance: Curative cancer operations lead to debility and loss of autonomy in a population vulnerable to suicide death. The extent to which operative intervention impacts suicide risk is not well studied.Objective: To examine the effects of morbidity of curative cancer surgeries and prognosis of disease on the risk of suicide in patients with solid tumors.Design: Retrospective cohort study using Surveillance, Epidemiology, and End Results data from 2004 to 2011; multilevel systematic review.Setting: General US population.Participants: Participants were 482 781 patients diagnosed with malignant neoplasm between 2004 and 2011 who underwent curative cancer surgeries.Main Outcomes and Measures: Death by suicide or self-inflicted injury.Results: Among 482 781 patients that underwent curative cancer surgery, 231 committed suicide (16.58/100 000 person-years [95% confidence interval, CI, 14.54-18.82]). Factors significantly associated with suicide risk included male sex (incidence rate [IR], 27.62; 95% CI, 23.82-31.86) and age >65 years (IR, 22.54; 95% CI, 18.84-26.76). When stratified by 30-day overall postoperative morbidity, a significantly higher incidence of suicide was found for high-morbidity surgeries (IR, 33.30; 95% CI, 26.50-41.33) vs moderate morbidity (IR, 24.27; 95% CI, 18.92-30.69) and low morbidity (IR, 9.81; 95% CI, 7.90-12.04). Unit increase in morbidity was significantly associated with death by suicide (odds ratio, 1.01; 95% CI, 1.00-1.03; P = .02) and decreased suicide-specific survival (hazards ratio, 1.02; 95% CI, 1.00-1.03, P = .01) in prognosis-adjusted models.Conclusions: In this sample of cancer patients in the Surveillance, Epidemiology, and End Results database, patients that undergo high-morbidity surgeries appear most vulnerable to death by suicide. The identification of this high-risk cohort should motivate health care providers and particularly surgeons to adopt screening measures during the postoperative follow-up period for these patients. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
