التفاصيل البيبلوغرافية
| العنوان: |
Bridging gaps in brain disconnection in childhood ADHD: From macroscale connectomes to microscale biological architectures. |
| المؤلفون: |
Chen, Boxuan1,2 (AUTHOR), Qin, Shaozheng1,2,3 (AUTHOR) szqin@bnu.edu.cn |
| المصدر: |
Psychiatry & Clinical Neurosciences. May2024, Vol. 78 Issue 5, p271-272. 2p. |
| مصطلحات موضوعية: |
*ATTENTION-deficit hyperactivity disorder |
| مستخلص: |
This article discusses the neuropathological mechanisms underlying childhood ADHD, focusing on the connection between macroscopic brain connectome aberrations and microscopic biological architectures. The study used neuroimaging data to examine functional connectivity in ADHD children and found perturbations in cortical gradients compared to typically developing peers. These gradient perturbations were associated with neurotransmitter receptors and genetic transcriptional expressions linked to episodic memory and emotional regulation. The article suggests further research into the specific mechanisms underlying brain connectome aberrations in ADHD and the developmental trajectories of these abnormalities. Early detection and interventions are important for managing ADHD and reducing its impact. [Extracted from the article] |
| قاعدة البيانات: |
Academic Search Index |
Full Text Finder