نتائج البحث

1

Degenerative and regenerative pathways underlying Duchenne muscular dystrophy revealed by single-nucleus RNA sequencing

المؤلفون: Zhaoning Wang, Eric N. Olson, Rhonda Bassel-Duby, Hui Li, Francesco Chemello, Ning Liu, John R. McAnally

المصدر: Proc Natl Acad Sci U S A

مصطلحات موضوعية: musculoskeletal diseases, congenital, hereditary, and neonatal diseases and abnormalities, Cell type, Transcription, Genetic, Duchenne muscular dystrophy, Muscle disorder, Dystrophin, Macular Degeneration, Mice, Exon, Multinucleate, Myofibrils, Commentaries, medicine, Animals, Regeneration, Humans, Myocyte, Gene Regulatory Networks, Muscle, Skeletal, Multidisciplinary, biology, Sequence Analysis, RNA, Skeletal muscle, Exons, Muscular Dystrophy, Animal, Biological Sciences, medicine.disease, Cell biology, Mice, Inbred C57BL, Muscular Dystrophy, Duchenne, Disease Models, Animal, medicine.anatomical_structure, Mutation, biology.protein, Transcriptome, Gene Deletion, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5d1a93adf459f6ebc9eb7fa1c33c7c1Test
https://doi.org/10.1073/pnas.2018391117Test

2

Igniting Ca 2+ sparks with TRPML1

المؤلفون: Gerard P. Sergeant, Keith D. Thornbury, Mark A. Hollywood

المصدر: Proceedings of the National Academy of Sciences. 117:32836-32838

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::13b6472eb3410ed5f102474574c0bd78Test
https://doi.org/10.1073/pnas.2022896117Test

3

The zebrafish grime mutant uncovers an evolutionarily conserved role for Tmem161b in the control of cardiac rhythm

المساهمون: Hubrecht Institute for Developmental Biology and Stem Cell Research, Medical Biology, ACS - Amsterdam Cardiovascular Sciences

المصدر: Proceedings of the National Academy of Sciences of the United States of America, 118(9). National Academy of Sciences
Proceedings of the National Academy of Sciences of the United States of America, 118(9):e2018220118. National Academy of Sciences

مصطلحات موضوعية: Periodicity, Embryo, Nonmammalian, Mouse, Forward genetics, Arrhythmias, Lethal, Animals, Genetically Modified, Mice, Myocyte, Developmental, Arrhythmias, Cardiac/genetics, Zebrafish, Conserved Sequence, Mice, Knockout, Nonmammalian, Multidisciplinary, biology, Gene Expression Regulation, Developmental, Heart Rate/genetics, Myocytes, Cardiac/metabolism, Cell biology, Embryo, Action Potentials/genetics, Cardiac/metabolism, Knockout mouse, Haploinsufficiency, Cardiac, Arrhythmia, Cardiac function curve, Calcium/metabolism, Knockout, Potassium/metabolism, Genetically Modified, Cardiac/genetics, Zebrafish Proteins/genetics, Animals, Membrane Proteins/genetics, Myocytes, Ion Transport, Base Sequence, Organogenesis/genetics, Animal, Mammalian, Cardiac arrhythmia, Embryo, Mammalian, biology.organism_classification, Disease Models, Animal, Gene Expression Regulation, Genes, Disease Models, Mutation, Genes, Lethal, Heart/embryology, Genetic screen