دورية أكاديمية

Synthesis of Highly Functionalized Imidazopyridine: A Simple One-Pot Three-Component Synthesis of 6-Hydroxy-5 -(3-Phenylimidazo[1,2-a]Pyridin-2-yl)-2-Thioxo-2, 3-Dihydropyrimidin-4(1H)-Ones.

التفاصيل البيبلوغرافية
العنوان: Synthesis of Highly Functionalized Imidazopyridine: A Simple One-Pot Three-Component Synthesis of 6-Hydroxy-5 -(3-Phenylimidazo[1,2-a]Pyridin-2-yl)-2-Thioxo-2, 3-Dihydropyrimidin-4(1H)-Ones.
المؤلفون: Asadi, Sara1 (AUTHOR), Zebarjad, Maedeh1 (AUTHOR), Mehrabi, Hossein1 (AUTHOR) h.mehrabi@vru.ac.ir
المصدر: Polycyclic Aromatic Compounds. 2023, Vol. 43 Issue 10, p9295-9305. 11p.
مصطلحات موضوعية: *IMIDAZOPYRIDINES, *BIOACTIVE compounds, *AMINOPYRIDINES, *GLYOXAL, *ACETIC acid
مستخلص: In this research, synthesis of different imidazopyridine derivatives was performed using aryl glyoxals, thiobarbituric acid, and 2-aminopyridine in the presence of acetic acid in ethanol at 80 °C. Different aryl glyoxals can be used in this method. Finally, the desired products were separated by simple filtration in excellent yields. The salient features of this protocol are a simple operation, mild reaction conditions, simple work up, easy product isolation, and preparation of potentially bioactive compounds. [ABSTRACT FROM AUTHOR]
قاعدة البيانات: Academic Search Index
الوصف
تدمد:10406638
DOI:10.1080/10406638.2022.2161583