التفاصيل البيبلوغرافية
| العنوان: |
Evaluation of bile sterility in patients undergoing liver resection. |
| المؤلفون: |
Piątek, Barbara1 md.barbara.piatek@gmail.com, Majos, Alicja1, Grząsiak, Oliwia1, Strzelczyk, Janusz1 |
| المصدر: |
Polish Journal of Surgery. 2022, Vol. 94 Issue 3, p39-43. 5p. |
| مصطلحات موضوعية: |
*LIVER surgery, *ASEPSIS & antisepsis, *ANTIBIOTIC prophylaxis, *LIVER cancer, *SURGICAL complications, *LIVER tumors, TUMOR surgery |
| مستخلص: |
Introduction: Surgery remains the mainstay of treatment for liver tumors. Significant differences in complication rates between liver surgery centers have been reported ranging from 4.1% up to 47.7%. There have been little papers or studies on the impact of bile infection on postoperative complications in patients undergoing surgery for liver cancer. Aim: The aim of our study was to assess the etiology of bile infections in patients following liver resection and to evaluate its impact on complications and perioperative mortality. Materials and methods: The studied material consisted of 69 patients undergoing surgery for liver tumors at the Department of General and Transplant Surgery of the Medical University of Lodz between 2011 and 2013, when the intraoperative bile cultures were available. Results: The intraoperative bile cultures were positive for bacteria in 12 cases (18.75%), while in other cases the bile was sterile (n = 52). In 41.61% of cases, a methicillin-resistant strain was identified. Two patients presented with jaundice, associated with abdominal pain in one patient; other patients complained of abdominal pain only (jaundice: 16.67%; abdominal pain: 91.67%). In both cases, jaundice was not accompanied by any other typical symptoms of cholangitis; also, palliative surgery was performed in both cases. In patients with confirmed bile infection, jaundice was significantly more common (16.67% vs 0.00%; p = 0.033). Patients with sterile bile cultures reported weight loss significantly more often compared to patients with bile infection (26.90% vs 0.00%; p = 0.042). The hospital stay was longer in patients with bile infection (p = 0.138), whereas the hospitalization was significantly longer in patients infected with methicillin-resistant strains compared to both patients with sterile bile and those with bile infection with non-resistant strains. Conclusions: The causes and real incidence of asymptomatic bile infection remain unknown. Routine bile cultures in patients undergoing liver surgery may prevent complications by early modification of antibiotic regime considering the antibiogram, and identification of the most common causes of asymptomatic bile infection may translate to better preoperative antibiotic prophylaxis. [ABSTRACT FROM AUTHOR] |
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