دورية أكاديمية
Clinical outcomes of EUS-guided drainage of debris-containing pancreatic pseudocysts: a large multicenter study
| العنوان: | Clinical outcomes of EUS-guided drainage of debris-containing pancreatic pseudocysts: a large multicenter study |
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| المؤلفون: | Yang, Dennis, Amin, Sunil, Gonzalez, Susana, Mullady, Daniel, Edmundowicz, Steven A., DeWitt, John M., Khashab, Mouen A., Wang, Andrew Y., Nagula, Satish, Buscaglia, Jonathan M., Bucobo, Juan Carlos, Wagh, Mihir S., Draganov, Peter V., Stevens, Tyler, Vargo, John J., Khara, Harshit S., Diehl, David L., Keswani, Rajesh N., Komanduri, Srinadh, Yachimski, Patrick S., Prabhu, Anoop, Kwon, Richard S., Watson, Rabindra R., Goodman, Adam J., Benias, Petros, Carr-Locke, David L., DiMaio, Christopher J. |
| المساهمون: | Department of Medicine, IU School of Medicine |
| المصدر: | PMC |
| بيانات النشر: | Thieme |
| سنة النشر: | 2017 |
| المجموعة: | Indiana University - Purdue University Indianapolis: IUPUI Scholar Works |
| مصطلحات موضوعية: | Endoscopic drainage, Debris-free pseudocysts, Solid debris pseudocysts, Transmural stents, Endoscopic ultrasound (EUS) |
| الوصف: | Background and study aims Data on clinical outcomes of endoscopic drainage of debris-free pseudocysts (PDF) versus pseudocysts containing solid debris (PSD) are very limited. The aims of this study were to compare treatment outcomes between patients with PDF vs. PSD undergoing endoscopic ultrasound (EUS)-guided drainage via transmural stents. Patients and methods Retrospective review of 142 consecutive patients with pseudocysts who underwent EUS-guided transmural drainage (TM) from 2008 to 2014 at 15 academic centers in the United States. Main outcome measures included TM technical success, treatment outcomes (symptomatic and radiologic resolution), need for endoscopic re-intervention at follow-up, and adverse events (AEs). Results TM was performed in 90 patients with PDF and 52 with PSD. Technical success: PDF 87 (96.7 %) vs. PSD 51 (98.1 %). There was no difference in the rates for endoscopic re-intervention (5.5 % in PDF vs. 11.5 % in PSD; P = 0.33) or AEs (12.2 % in PDF vs. 19.2 % in PSD; P = 0.33). Median long-term follow-up after stent removal was 297 days (interquartile range [IQR]: 59 - 424 days) for PDF and 326 days (IQR: 180 - 448 days) for PSD (P = 0.88). There was a higher rate of short-term radiologic resolution of PDF (45; 66.2 %) vs. PSD (21; 51.2 %) (OR = 0.30; 95 % CI: 0.13 - 0.72; P = 0.009). There was no difference in long-term symptomatic resolution (PDF: 70.4 % vs. PSD: 66.7 %; P = 0.72) or radiologic resolution (PDF: 68.9 % vs. PSD: 78.6 %; P = 0.72) Conclusions There was no difference in need for endoscopic re-intervention, AEs or long-term treatment outcomes in patients with PDF vs. PSD undergoing EUS-guided drainage with transmural stents. Based on these results, the presence of solid debris in pancreatic fluid collections does not appear to be associated with a poorer outcome. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| العلاقة: | Endoscopy International Open; Yang, D., Amin, S., Gonzalez, S., Mullady, D., Edmundowicz, S. A., DeWitt, J. M., … DiMaio, C. J. (2017). Clinical outcomes of EUS-guided drainage of debris-containing pancreatic pseudocysts: a large multicenter study. Endoscopy International Open, 5(2), E130–E136. http://doi.org/10.1055/s-0042-121666Test; https://hdl.handle.net/1805/13173Test |
| الإتاحة: | https://doi.org/10.1055/s-0042-121666Test https://hdl.handle.net/1805/13173Test |
| حقوق: | Publisher Policy |
| رقم الانضمام: | edsbas.F24F3D1E |
| قاعدة البيانات: | BASE |
| الوصف غير متاح. |