دورية أكاديمية
Diabetic foot ulcers: Retrospective comparative analysis from Sicily between two eras
| العنوان: | Diabetic foot ulcers: Retrospective comparative analysis from Sicily between two eras |
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| المؤلفون: | Valentina Guarnotta, Stefano Radellini, Enrica Vigneri, Achille Cernigliaro, Felicia Pantò, Salvatore Scondotto, Piero Luigi Almasio, Giovanni Guercio, Carla Giordano |
| المصدر: | PLoS ONE, Vol 16, Iss 12 (2021) |
| بيانات النشر: | Public Library of Science (PLoS), 2021. |
| سنة النشر: | 2021 |
| المجموعة: | LCC:Medicine LCC:Science |
| مصطلحات موضوعية: | Medicine, Science |
| الوصف: | Aim The aim of this study was to analyze changes in the incidence, management and mortality of DFU in Sicilian Type 2 diabetic patients hospitalized between two eras, i.e. 2008–2013 and 2014–2019. Methods We compared the two eras, era1: 2008–13, era2: 2014–19. In era 1, n = 149, and in era 2, n = 181 patients were retrospectively enrolled. Results In the population hospitalized for DFU in 2008–2013, 59.1% of males and 40.9% of females died, whilst in 2014–2019 65.9% of males and 34.1% of females died. Moderate chronic kidney disease (CKD) was significantly higher in patients that had died than in ones that were alive (33% vs. 43%, p < 0.001), just as CKD was severe (14.5% vs. 4%, p < 0.001). Considering all together the risk factors associated with mortality, at Cox regression multivariate analysis only moderate-severe CKD (OR 1.61, 95% CI 1.07–2.42, p 0.021), age of onset greater than 69 years (OR 2.01, 95% CI 1.37–2.95, p Conclusions Patients with DFU have high mortality and reduced life expectancy. Age at onset of diabetic foot ulcer, eGFR values and CKD are the principal risk factors for mortality. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1932-6203 |
| العلاقة: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8651101/?tool=EBITest; https://doaj.org/toc/1932-6203Test |
| الوصول الحر: | https://doaj.org/article/14879137a14f4f339e999aca68800dc6Test |
| رقم الانضمام: | edsdoj.14879137a14f4f339e999aca68800dc6 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 19326203 |
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