التفاصيل البيبلوغرافية
| العنوان: |
Factors That Influence Parental Attitudes toward Enrollment in Type 1 Diabetes Trials. |
| المؤلفون: |
Buscariollo, Daniela L., Davidson, Mario A., Black, Margo, Russell, William E., Rothman, Russell L., Moore, Daniel J., Giorgino, Francesco |
| المصدر: |
PLoS ONE; Aug2012, Vol. 7 Issue 8, Special section p1-8, 8p |
| مصطلحات موضوعية: |
TYPE 2 diabetes, CLINICAL trials, DIABETES, CROSS-sectional method, SURVEYS, PLACEBOS |
| مستخلص: |
Aims: To assess parental attitudes towards type 1 diabetes clinical trials (T1DCTs) and factors that impact willingness to enroll their children with and without diabetes. Methods: A cross-sectional survey of parents of children with type 1 diabetes was administered at an academic clinic and a diabetes educational event. Results: Survey response rate was 36%. Of 166 participating parents, 76% were aware of T1DCTs. More parents reported willingness to enroll children with diabetes (47%) than unaffected children (36%). Only 18% recalled being asked to enroll their children, and of these, 60% agreed to enroll at least some of those times. Less than 30% were comfortable with placebos. Factors predicting willingness to enroll children with diabetes included healthcare provider trust, comfort with consent by proxy, low fear of child being a "guinea pig," and comfort with placebo. Factors predicting willingness to enroll unaffected children were provider trust, comfort with consent by proxy, comfort with placebo, and perceived ease of understanding T1DCT information. Conclusions: Parents report moderate willingness to enroll children in T1DCTs. Willingness is diminished by common trial methodologies. Although most parents recalled receiving trial-related information, significantly fewer recalled being asked to participate. Efforts to optimize effective communication around identified areas of parental concern may increase T1DCT participation. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
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