Local cattle and badger populations affect the risk of confirmed tuberculosis in British cattle herds
| العنوان: | Local cattle and badger populations affect the risk of confirmed tuberculosis in British cattle herds |
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| المؤلفون: | W. Thomas Johnston, Christl A. Donnelly, Flavie Vial |
| المساهمون: | Medical Research Council (MRC) |
| المصدر: | PLoS ONE PLoS ONE, Vol 6, Iss 3, p e18058 (2011) |
| سنة النشر: | 2010 |
| مصطلحات موضوعية: | Immunity, Herd, Veterinary medicine, Time Factors, Badger, Epidemiology, animal diseases, ENGLAND, Population Dynamics, Veterinary Microbiology, lcsh:Medicine, Animal Slaughter, Culling, Wildlife, law.invention, law, Risk Factors, Science Policy and Economics, Bovine Tuberculosis, WILD BOAR, lcsh:Science, Animal Management, Multidisciplinary, biology, Ecology, Zoonotic Diseases, Great Britain, Agriculture, ASSOCIATION, Veterinary Bacteriology, Transmission (mechanics), Veterinary Diseases, HUSBANDRY PRACTICES, Science & Technology - Other Topics, Livestock, MYCOBACTERIUM-BOVIS INFECTIONS, Research Article, Veterinary Medicine, STRATEGIES, General Science & Technology, Science Policy, Animal Types, Mustelidae, Meles, Large Animals, Animal Welfare, Models, Biological, Herd immunity, Veterinary Epidemiology, FARMS, biology.animal, Environmental health, MD Multidisciplinary, Animals, Biology, BREAKDOWNS, Science & Technology, REPUBLIC-OF-IRELAND, Population Biology, MULTIDISCIPLINARY SCIENCES, business.industry, lcsh:R, Reproducibility of Results, Bioethics, biology.organism_classification, Health Surveys, United Kingdom, Multivariate Analysis, Herd, lcsh:Q, Cattle, Veterinary Science, business, Tuberculosis, Bovine, Zoology, Agroecology |
| الوصف: | Background The control of bovine tuberculosis (bTB) remains a priority on the public health agenda in Great Britain, after launching in 1998 the Randomised Badger Culling Trial (RBCT) to evaluate the effectiveness of badger (Meles meles) culling as a control strategy. Our study complements previous analyses of the RBCT data (focusing on treatment effects) by presenting analyses of herd-level risks factors associated with the probability of a confirmed bTB breakdown in herds within each treatment: repeated widespread proactive culling, localized reactive culling and no culling (survey-only). Methodology/Principal Findings New cases of bTB breakdowns were monitored inside the RBCT areas from the end of the first proactive badger cull to one year after the last proactive cull. The risk of a herd bTB breakdown was modeled using logistic regression and proportional hazard models adjusting for local farm-level risk factors. Inside survey-only and reactive areas, increased numbers of active badger setts and cattle herds within 1500 m of a farm were associated with an increased bTB risk. Inside proactive areas, the number of M. bovis positive badgers initially culled within 1500 m of a farm was the strongest predictor of the risk of a confirmed bTB breakdown. Conclusions/Significance The use of herd-based models provide insights into how local cattle and badger populations affect the bTB breakdown risks of individual cattle herds in the absence of and in the presence of badger culling. These measures of local bTB risks could be integrated into a risk-based herd testing programme to improve the targeting of interventions aimed at reducing the risks of bTB transmission. |
| تدمد: | 1932-6203 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b2f3bd60824422b8a56e44e2d7cecbbTest https://pubmed.ncbi.nlm.nih.gov/21464920Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....5b2f3bd60824422b8a56e44e2d7cecbb |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 19326203 |
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