المؤلفون: J Willem M Nissink, Michal Bista, Jason Breed, Nikki Carter, Kevin Embrey, Jonathan Read, Jon J Winter-Holt

المصدر: PLoS ONE, Vol 11, Iss 3, p e0151154 (2016)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

العلاقة: http://europepmc.org/articles/PMC4801406?pdf=renderTest; https://doaj.org/toc/1932-6203Test

الوصول الحر: https://doaj.org/article/9fb8b358bc4f48ecb81ceedb4cb0f8a9Test

المؤلفون: Julie A Tucker, Neil Bennett, Claire Brassington, Stephen T Durant, Giles Hassall, Geoff Holdgate, Mark McAlister, J Willem M Nissink, Caroline Truman, Martin Watson

المصدر: PLoS ONE, Vol 7, Iss 12, p e50889 (2012)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

العلاقة: http://europepmc.org/articles/PMC3519477?pdf=renderTest; https://doaj.org/toc/1932-6203Test

الوصول الحر: https://doaj.org/article/1111696dd18f4d99a4a0e476ab6e5256Test

المؤلفون: Petra van der Stoop, Erwin A Boutsma, Danielle Hulsman, Sonja Noback, Mike Heimerikx, Ron M Kerkhoven, J Willem Voncken, Lodewyk F A Wessels, Maarten van Lohuizen

المصدر: PLoS ONE, Vol 3, Iss 5, p e2235 (2008)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

العلاقة: http://europepmc.org/articles/PMC2375055?pdf=renderTest; https://doaj.org/toc/1932-6203Test

الوصول الحر: https://doaj.org/article/72cd3015ec06429d8a7c567a79714969Test

المؤلفون: J. Willem M. Nissink, Neil Bennett, Mark S. B. McAlister, Stephen T. Durant, Julie A. Tucker, Martin J Watson, Claire Brassington, Giles Hassall, Caroline Truman, Geoff Holdgate

المصدر: PLoS ONE
PLoS ONE, Vol 7, Iss 12, p e50889 (2012)

مصطلحات موضوعية: Protein Structure, Glycoside Hydrolases, Protein Conformation, Biophysics, lcsh:Medicine, DNA repair, Biochemistry, chemistry.chemical_compound, Structure-Activity Relationship, Protein structure, Catalytic Domain, Ribose, Drug Discovery, Molecular Cell Biology, Macromolecular Structure Analysis, Structure–activity relationship, Humans, Biomacromolecule-Ligand Interactions, lcsh:Science, Poly(ADP-ribose) glycohydrolase, Biology, chemistry.chemical_classification, PARG, Multidisciplinary, lcsh:R, Computational Biology, Proteins, Isothermal titration calorimetry, DNA, Small molecule, Enzymes, Nucleic acids, Enzyme, chemistry, Enzyme Structure, lcsh:Q, Research Article, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77341b32dbe7d1991fde879d04fc11acTest
https://pubmed.ncbi.nlm.nih.gov/23251397Test

المؤلفون: Jonathan Read, Jason Breed, J. Willem M. Nissink, Michal Bista, Jon Winter-Holt, Kevin J. Embrey, Nikki Carter

المصدر: PLoS ONE
PLoS ONE, Vol 11, Iss 3, p e0151154 (2016)

مصطلحات موضوعية: 0301 basic medicine, Magnetic Resonance Spectroscopy, Ribose, Amino Acid Motifs, lcsh:Medicine, Crystallography, X-Ray, Physical Chemistry, Biochemistry, Protein Structure, Secondary, Substrate Specificity, 0302 clinical medicine, Protein structure, Macromolecular Structure Analysis, lcsh:Science, Crystallography, Multidisciplinary, Organic Compounds, Nucleotides, Chemistry, Physics, Monosaccharides, Deoxyguanine Nucleotides, Nuclear magnetic resonance spectroscopy, Condensed Matter Physics, Bioassays and Physiological Analysis, 030220 oncology & carcinogenesis, Physical Sciences, Crystal Structure, Pharmacophore, Two-dimensional nuclear magnetic resonance spectroscopy, Research Article, Chemical Elements, Protein Structure, Guanine, Carbohydrates, Research and Analysis Methods, 03 medical and health sciences, Hydrolase, Solid State Physics, Molecule, Binding site, Molecular Biology, Enzyme Assays, Aspartic Acid, Binding Sites, Nucleobases, Chemical Bonding, lcsh:R, Organic Chemistry, Chemical Compounds, Water, Biology and Life Sciences, Proteins, Substrate (chemistry), Hydrogen Bonding, Combinatorial chemistry, Phosphoric Monoester Hydrolases, Oxygen, Kinetics, 030104 developmental biology, lcsh:Q, Biochemical Analysis

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc6181c4e91b525dbf36a8991b5f10baTest
https://doi.org/10.1371/journal.pone.0151154Test

المؤلفون: Mike Heimerikx, Danielle Hulsman, Lodewyk F. A. Wessels, Erwin Boutsma, Ron M. Kerkhoven, Petra van der Stoop, Maarten van Lohuizen, J. Willem Voncken, Sonja Noback

المصدر: PLoS ONE
PLoS ONE, Vol 3, Iss 5, p e2235 (2008)

مصطلحات موضوعية: Cellular differentiation, Ubiquitin-Protein Ligases, lcsh:Medicine, macromolecular substances, Molecular Biology/Histone Modification, Histones, Mice, Ubiquitin, Genetics and Genomics/Epigenetics, Histone H2A, Animals, lcsh:Science, Promoter Regions, Genetic, Cells, Cultured, Embryonic Stem Cells, Cell Biology/Gene Expression, Mice, Knockout, Polycomb Repressive Complex 1, Multidisciplinary, biology, Gene Expression Profiling, lcsh:R, Genetics and Genomics/Gene Expression, Embryonic stem cell, Molecular biology, Ubiquitin ligase, Developmental Biology/Stem Cells, DNA-Binding Proteins, Repressor Proteins, Histone, biology.protein, Developmental Biology/Cell Differentiation, lcsh:Q, CpG Islands, Stem cell, PRC1, Research Article

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eaf4cb9e343598901ea710b6c1d7ead9Test
https://pubmed.ncbi.nlm.nih.gov/18493325Test

المؤلفون: Nissink, J. Willem M.¹ willem.nissink@astrazeneca.com, Bista, Michal², Breed, Jason², Carter, Nikki², Embrey, Kevin³, Read, Jonathan², Winter-Holt, Jon J.¹

المصدر: PLoS ONE. 3/21/2016, Vol. 11 Issue 3, p1-16. 16p.

مصطلحات موضوعية: *ONCOLOGIC surgery, *DNA damage, *X-ray detection, *PROMISCUITY, *PREVENTION

المؤلفون: Tucker, Julie A., Bennett, Neil, Brassington, Claire, Durant, Stephen T., Hassall, Giles, Holdgate, Geoff, McAlister, Mark, Nissink, J. Willem M., Truman, Caroline, Watson, Martin

المصدر: PLoS ONE; Dec2012, Vol. 7 Issue 12, p1-19, 19p

مصطلحات موضوعية: ENZYMES, POLYMERS, PYROPHOSPHATES, CALORIMETRY, GENES, DEATH

المؤلفون: van der Stoop, Petra, Boutsma, Erwin A., Hulsman, Danielle, Noback, Sonja, Heimerikx, Mike, Kerkhoven, Ron M., Voncken, J. Willem, Wessels, Lodewyk F. A., van Lohuizen, Maarten

المصدر: PLoS ONE; 2008, Vol. 3 Issue 5, p1-14, 14p, 1 Color Photograph, 1 Black and White Photograph, 1 Diagram, 1 Chart, 3 Graphs

مصطلحات موضوعية: UBIQUITIN, LIGASES, EMBRYONIC stem cells, LABORATORY mice, GENE expression, CELLULAR control mechanisms, CELL communication, ALKALINE phosphatase, HISTONES

المؤلفون: P M den Reijer, E M Haisma, N A Lemmens-den Toom, J Willemse, R I Koning, J A A Demmers, D H W Dekkers, E Rijkers, A El Ghalbzouri, P H Nibbering, W van Wamel

المصدر: PLoS ONE, Vol 11, Iss 1, p e0145722 (2016)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

العلاقة: http://europepmc.org/articles/PMC4704740?pdf=renderTest; https://doaj.org/toc/1932-6203Test

الوصول الحر: https://doaj.org/article/466cfdf2dab44e1d85036dfda2ec9fb5Test