Accurate determination of phenotypic information from historic thoroughbred horses by single base extension
| العنوان: | Accurate determination of phenotypic information from historic thoroughbred horses by single base extension |
|---|---|
| المؤلفون: | Fleischer, Robert C., Campana, Michael G., Whitten, C. Mark, Edwards, Ceiridwen J., Stock, Frauke, Murphy, Angela M., Binns, Matthew M., Barker, Graeme W. W., Bower, Mim A. |
| المصدر: | PLoS ONE PLoS ONE, Vol 5, Iss 12, p e15172 (2010) |
| سنة النشر: | 2010 |
| مصطلحات موضوعية: | Evolutionary Genetics, Archeology, Heredity, Genotype, Pedigree information, Genotypes, lcsh:Medicine, Single-nucleotide polymorphism, Pedigree chart, Biology, Q1, Polymerase Chain Reaction, Polymorphism, Single Nucleotide, Molecular Genetics, Genetics, Animals, Typing, Horses, Allele, lcsh:Science, Genetics (life sciences), Genotyping, Alleles, DNA Primers, Evolutionary Biology, Multidisciplinary, lcsh:R, Paleontology, Computational Biology, DNA, Sequence Analysis, DNA, Single-base extension, Pedigree, Ancient DNA, Phenotype, Evolutionary biology, lcsh:Q, Sequence Analysis, Animal Genetics, Population Genetics, Research Article, Biotechnology |
| الوصف: | Historic DNA data have the potential to identify phenotypic information otherwise invisible in the historical, archaeological and palaeontological record. In order to determine whether a single nucleotide polymorphism typing protocol based on single based extension (SNaPshot™) could produce reliable phenotypic data from historic samples, we genotyped three coat colour markers for a sample of historic Thoroughbred horses for which both phenotypic and correct genotypic information were known from pedigree information in the General Stud Book. Experimental results were consistent with the pedigrees in all cases. Thus we demonstrate that historic DNA techniques can produce reliable phenotypic information from museum specimens. |
| وصف الملف: | application/pdf |
| تدمد: | 1932-6203 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3d43f1fe5f43e59a198c7eb4e7f2f44Test https://pubmed.ncbi.nlm.nih.gov/21152043Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....e3d43f1fe5f43e59a198c7eb4e7f2f44 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 19326203 |
|---|