Comparison of the Hematological Profile of Elite Road Cyclists during the 2010 and 2012 GiroBio Ten-Day Stage Races and Relationships with Final Ranking
| العنوان: | Comparison of the Hematological Profile of Elite Road Cyclists during the 2010 and 2012 GiroBio Ten-Day Stage Races and Relationships with Final Ranking |
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| المؤلفون: | Marco Bonifazi, Franco M. Impellizzeri, Giovanni Lombardi, Giuseppe Banfi, Luigi Simonetto, Massimo Locatelli, Pier Luigi Fiorella, Patrizia Lanteri |
| المساهمون: | Lombardi, G, Lanteri, P, Fiorella, Pl, Simonetto, L, Impellizzeri, Fm, Bonifazi, M, Banfi, Giuseppe, Locatelli, M. |
| المصدر: | PLoS ONE, Vol 8, Iss 4, p e63092 (2013) PLoS ONE |
| بيانات النشر: | Public Library of Science (PLoS), 2013. |
| سنة النشر: | 2013 |
| مصطلحات موضوعية: | Adult, Male, Platelets, Anatomy and Physiology, Heme Synthesis, Red Cells, lcsh:Medicine, Mean corpuscular hemoglobin, Physiology, Hematocrit, Cardiovascular System, Biochemistry, Young Adult, White blood cell, medicine, Humans, Sports and Exercise Medicine, lcsh:Science, Biology, Mean corpuscular volume, Hematologic Tests, Multidisciplinary, medicine.diagnostic_test, business.industry, lcsh:R, Anemia, Hematology, Bicycling, Hematopoiesis, medicine.anatomical_structure, Blood chemistry, Athletes, Blood Chemistry, Immunology, Circulatory Physiology, Medicine, Population study, lcsh:Q, Hemoglobin, business, Blood Chemical Analysis, Research Article, Blood drawing |
| الوصف: | Cycling stage races are strenuous endurance events during which exercise-induced variations in hematological parameters are consistently observed. However, specific literature on such changes is scarce and published data have been derived from small samples of athletes. The aims of this study were: (1) to determine the hematological response to middle-term strenuous endurance; and (2) to determine whether a relationship exists between the athlete-specific hematological profile and final placement in a cycling stage race. The study population was male professional cyclists (n = 253) competing in the 2010 (n = 144) and 2012 (n = 109) GiroBio 10-day stage races. Blood draws taken before the start of the race, at mid-race, and at end-race were performed in strict compliance with academic and anti-doping pre-analytical warnings. Blood chemistry included white blood cell, red blood cell, hemoglobin concentration, hematocrit, mean corpuscular volume (MCV), mean hemoglobin content (MCH), mean corpuscular hemoglobin content (MCHC), platelets, and reticulocyte relative and absolute counts. Compared to baseline values, erythrocyte, hemoglobin, hematocrit, MCHC, platelet and reticulocyte counts were all consistently lower at mid-race, but returned to normal by race-end, while leukocytes were increased in the final phase. MCV increased during both events. MCH increased in the first part to then return to baseline in the 2012 race. The calculated OFF-score consistently decreased in the first half of the race before increasing, but remained lower than the baseline value. The trends of variation in hematological parameters were substantially similar in both events. There was an inverse, albeit weak, relationship between placement and erythrocyte, platelet, hemoglobin, hematocrit and OFF-score values in the 2010, but not in the 2012 race. In conclusion, the data confirm that, in this large series of elite road cyclists, the strenuous effort a rider sustains during a stage race induces appreciable changes in the hematological profile. |
| تدمد: | 1932-6203 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d0d8f2579abca6521fcac5e33d6c691Test https://doi.org/10.1371/journal.pone.0063092Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....2d0d8f2579abca6521fcac5e33d6c691 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 19326203 |
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