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المؤلفون: George Van Buren, Changyi Chen, Dongliang Liu, Zhengdong Liang, Ethan Poteet, Qizhi Yao
المصدر: PLoS ONE
PLoS ONE, Vol 14, Iss 3, p e0213294 (2019)مصطلحات موضوعية: 0301 basic medicine, MAPK/ERK pathway, Cell signaling, endocrine system diseases, Kinase Inhibitors, Protein Expression, Cancer Treatment, Cetuximab, Signal transduction, Cell morphology, Biochemistry, 0302 clinical medicine, Antineoplastic Combined Chemotherapy Protocols, Medicine and Health Sciences, Tumor Cells, Cultured, Enzyme assays, Colorimetric assays, Cell Cycle and Cell Division, Enzyme Inhibitors, Bioassays and physiological analysis, EGFR inhibitors, Trametinib, Multidisciplinary, MTT assay, biology, Chemistry, Cell Cycle, Signaling cascades, Gefitinib, 3. Good health, ErbB Receptors, Oncology, Cell Processes, 030220 oncology & carcinogenesis, Mesothelin, Medicine, medicine.drug, Research Article, Carcinoma, Pancreatic Ductal, Pyridones, Science, Tyrosine Kinase Inhibitors, Pyrimidinones, GPI-Linked Proteins, 03 medical and health sciences, Pancreatic Cancer, Gastrointestinal Tumors, medicine, Gene Expression and Vector Techniques, Humans, Molecular Biology Techniques, neoplasms, Cell Cycle Inhibitors, Molecular Biology, Cell Proliferation, Molecular Biology Assays and Analysis Techniques, Biology and Life Sciences, Cancers and Neoplasms, Cell Biology, Transforming Growth Factor alpha, Gemcitabine, digestive system diseases, Research and analysis methods, Pancreatic Neoplasms, 030104 developmental biology, TGF-beta signaling cascade, Drug Resistance, Neoplasm, Biochemical analysis, biology.protein, Cancer research, Enzymology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b980dfd897c32964d5e49efe0e27edeTest
http://europepmc.org/articles/PMC6438513Test -
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المؤلفون: Shawn J. Rice, Xin Liu, Hong Gang Wang, Chandra P. Belani
المصدر: PLoS ONE, Vol 14, Iss 5, p e0217657 (2019)
PLoS ONEمصطلحات موضوعية: 0301 basic medicine, Cell signaling, medicine.medical_treatment, Protein Expression, Cancer Treatment, Apoptosis, Signal transduction, Lung and Intrathoracic Tumors, Targeted therapy, 0302 clinical medicine, Spectrum Analysis Techniques, Carcinoma, Non-Small-Cell Lung, Medicine and Health Sciences, Medicine, Phosphorylation, EGFR inhibitors, Multidisciplinary, medicine.diagnostic_test, Cell Death, Pharmaceutics, Flow Cytometry, ErbB Receptors, Oncogene Protein v-akt, Oncology, Proto-Oncogene Proteins c-bcl-2, Cell Processes, Spectrophotometry, 030220 oncology & carcinogenesis, Cytophotometry, EGFR signaling, Research Article, Cell Survival, Science, bcl-X Protein, Antineoplastic Agents, Research and Analysis Methods, Flow cytometry, 03 medical and health sciences, Drug Therapy, Cell Line, Tumor, Carcinoma, Gene Expression and Vector Techniques, Humans, Pyrroles, Lung cancer, Molecular Biology Techniques, Molecular Biology, Molecular Biology Assays and Analysis Techniques, business.industry, Cancer, Biology and Life Sciences, Cancers and Neoplasms, Cell Biology, medicine.disease, Non-Small Cell Lung Cancer, 030104 developmental biology, Cell culture, Drug Resistance, Neoplasm, Mutation, Cancer research, Myeloid Cell Leukemia Sequence 1 Protein, business
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dbae5ae9ec604f10f10c3e5280d19d5Test
https://doaj.org/article/a7ad9fd966d24fb9bb72eeadce9a3546Test -
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المؤلفون: Chuyang Han, Guang Li, Chaonan Sun, Qiao Qiao, Miao Zhang, Ning Han, Yuanjun Jiang
المصدر: PLoS ONE, Vol 12, Iss 12, p e0188932 (2017)
PLoS ONEمصطلحات موضوعية: 0301 basic medicine, DNA Repair, medicine.medical_treatment, Protein Expression, Cancer Treatment, Cetuximab, lcsh:Medicine, Apoptosis, Endoplasmic Reticulum, Radiation Tolerance, Biochemistry, 0302 clinical medicine, Medicine and Health Sciences, Small interfering RNAs, lcsh:Science, Endoplasmic Reticulum Chaperone BiP, Heat-Shock Proteins, EGFR inhibitors, Multidisciplinary, Secretory Pathway, Cell Death, Endoplasmic Reticulum Stress, ErbB Receptors, Nucleic acids, Oropharyngeal Neoplasms, Oncology, Cell Processes, 030220 oncology & carcinogenesis, Carcinoma, Squamous Cell, Cellular Structures and Organelles, medicine.drug, Signal Transduction, Research Article, Clinical Oncology, Autophagic Cell Death, Radiation Therapy, Protein Serine-Threonine Kinases, Research and Analysis Methods, Carcinomas, 03 medical and health sciences, Radioresistance, Cell Line, Tumor, Endoribonucleases, medicine, Carcinoma, Autophagy, Genetics, Gene Expression and Vector Techniques, Humans, Radiosensitivity, Molecular Biology Techniques, Non-coding RNA, Molecular Biology, neoplasms, Molecular Biology Assays and Analysis Techniques, Biology and life sciences, business.industry, lcsh:R, Cancers and Neoplasms, DNA, Cell Biology, medicine.disease, digestive system diseases, Activating Transcription Factor 6, Gene regulation, Radiation therapy, 030104 developmental biology, Oropharyngeal Carcinoma, Cancer research, RNA, lcsh:Q, Gene expression, Clinical Medicine, business, DNA Damage
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::363755df7543e9bd3b2d2046d5b89d84Test
http://europepmc.org/articles/PMC5726659?pdf=renderTest -
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المؤلفون: Hyun-Jin Kim, Eaum Seok Lee, Bon Jeong Ku, Ji Min Kim, Kyong Hye Joung, Sorim Choung
المصدر: PLoS ONE, Vol 14, Iss 2, p e0210828 (2019)
PLoS ONEمصطلحات موضوعية: Male, 0301 basic medicine, Cell signaling, Steatosis, Signal transduction, Pathology and Laboratory Medicine, Chronic liver disease, Biochemistry, Cytopathology, Mice, 0302 clinical medicine, Non-alcoholic Fatty Liver Disease, Medicine and Health Sciences, EGFR inhibitors, Multidisciplinary, Liver Diseases, Fatty Acids, Fatty liver, Lipids, ErbB Receptors, Cholesterol, Protein kinase B signaling, Lipogenesis, Medicine, lipids (amino acids, peptides, and proteins), EGFR signaling, Research Article, Cell biology, medicine.medical_specialty, Science, DNA transcription, 030209 endocrinology & metabolism, Gastroenterology and Hepatology, Diabetes Mellitus, Experimental, 03 medical and health sciences, Cell Line, Tumor, Internal medicine, Genetics, medicine, Animals, Humans, business.industry, Biology and Life Sciences, nutritional and metabolic diseases, Lipid metabolism, Lipid Metabolism, medicine.disease, Dietary Fats, digestive system diseases, Fatty Liver, Metabolism, 030104 developmental biology, Endocrinology, Anatomical Pathology, Quinazolines, Gene expression, business, Diet-induced obese
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::127a90092e724b77782e7c58a3be87feTest
https://doi.org/10.1371/journal.pone.0210828Test -
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المؤلفون: Frank Saran, Laura Clifton-Hadley, Stephen Nash, Daniel Krell, Mark Phillips, Paul Mulholland, Katharina Wanek, Iftekhar Khan, Catherine McBain, Nicholas F. Brown, Fiona Dungey, Paul Smith, Sarah Jeffries, Paul Sanghera, Kirsten Hopkins
المصدر: PLoS ONE, Vol 11, Iss 5, p e0156369 (2016)
PLoS ONEمصطلحات موضوعية: 0301 basic medicine, Oncology, Male, Vascular Endothelial Growth Factor A, Cell signaling, Physiology, Cancer Treatment, Phases of clinical research, lcsh:Medicine, Pharmacology, Signal transduction, Toxicology, Pathology and Laboratory Medicine, Placebos, 0302 clinical medicine, Endocrinology, Recurrence, Medicine and Health Sciences, Blastomas, Molecular Targeted Therapy, lcsh:Science, Neurological Tumors, EGFR inhibitors, Multidisciplinary, Gefitinib, Middle Aged, ErbB Receptors, Neurology, Research Design, 030220 oncology & carcinogenesis, Disease Progression, Female, Safety, EGFR signaling, medicine.drug, Research Article, Adult, medicine.medical_specialty, Cell biology, Clinical Research Design, Antineoplastic Agents, Surgical and Invasive Medical Procedures, Placebo, Research and Analysis Methods, Cediranib, 03 medical and health sciences, Internal medicine, Growth Factors, medicine, Humans, Progression-free survival, neoplasms, Aged, Surgical Resection, Endocrine Physiology, Epidermal Growth Factor, Toxicity, business.industry, lcsh:R, Cancers and Neoplasms, Biology and Life Sciences, Lomustine, Health Care, 030104 developmental biology, Quality of Life, Quinazolines, lcsh:Q, Adverse Events, business, Glioblastoma, Chemoradiotherapy, Glioblastoma Multiforme
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e527d383af2f1249eea01314b975d943Test
http://ora.ox.ac.uk/objects/uuidTest: -
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المؤلفون: Kazunori Yamaguchi, Setsuko Moriya, Kohta Takahashi, Masahiro Hosono, Kazuhiro Shiozaki, Koji Yamamoto, Hiroshi Shima, Taeko Miyagi
المصدر: PLoS ONE
PLoS ONE, Vol 10, Iss 3, p e0120578 (2015)مصطلحات موضوعية: MAPK/ERK pathway, Male, Carcinogenesis, lcsh:Medicine, Mice, Nude, Neuraminidase, Biology, Transfection, Mice, Epidermal growth factor, Gangliosides, Animals, Humans, lcsh:Science, Clonogenic assay, Protein kinase B, EGFR inhibitors, Cell Proliferation, Mice, Inbred BALB C, Multidisciplinary, Epidermal Growth Factor, lcsh:R, Up-Regulation, Enzyme Activation, ErbB Receptors, Gene Expression Regulation, Neoplastic, src-Family Kinases, Cancer cell, Cancer research, NIH 3T3 Cells, lcsh:Q, Signal transduction, Proto-oncogene tyrosine-protein kinase Src, Research Article, Signal Transduction
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05857c1a319e944b51f3fec76950287fTest
http://europepmc.org/articles/PMC4372364Test -
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المؤلفون: Guo-bin Huang, Pinjia Chen, Bin Li, Xiurong Yu, De-qing Zheng, Xiaoyong Luo, Yun-feng Lou, Zheng-zhi Zou
المصدر: PLoS ONE
PLoS ONE, Vol 9, Iss 5, p e97719 (2014)مصطلحات موضوعية: Colorectal cancer, Cell Survival, Cancer Treatment, Decitabine, lcsh:Medicine, Antineoplastic Agents, Apoptosis, Biology, Pharmacology, Gefitinib, Cell Line, Tumor, Basic Cancer Research, medicine, Medicine and Health Sciences, Humans, Epidermal growth factor receptor, lcsh:Science, Protein Kinase Inhibitors, PI3K/AKT/mTOR pathway, EGFR inhibitors, Adaptor Proteins, Signal Transducing, Multidisciplinary, Dose-Response Relationship, Drug, TOR Serine-Threonine Kinases, lcsh:R, Intracellular Signaling Peptides and Proteins, Cancer, Drug Synergism, DNA Methylation, medicine.disease, Neoplasm Proteins, Oncology, Colonic Neoplasms, biology.protein, Azacitidine, Quinazolines, lcsh:Q, Oncology Agents, Apoptosis Regulatory Proteins, Proto-Oncogene Proteins c-akt, medicine.drug, Research Article, Signal Transduction
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ff541a328b697fcad3e9cea77f7b61aTest
http://europepmc.org/articles/PMC4038521Test -
8Involvement of TNF-α converting enzyme in the development of psoriasis-like lesions in a mouse model
المؤلفون: Mikiro Takaishi, Kenji Sato, Shigetoshi Sano, Shota Tokuoka
المصدر: PLoS ONE, Vol 9, Iss 11, p e112408 (2014)
PLoS ONEمصطلحات موضوعية: Cell biology, Cell signaling, Angiogenesis, medicine.medical_treatment, Immunology, lcsh:Medicine, Autoimmunity, Dermatology, Signal transduction, chemistry.chemical_compound, Amphiregulin, Psoriasis, Molecular Cell Biology, Medicine and Health Sciences, Medicine, lcsh:Science, EGFR inhibitors, Multidisciplinary, Biology and life sciences, business.industry, Growth factor, lcsh:R, medicine.disease, Vascular endothelial growth factor, STAT signaling, chemistry, Cancer research, Tumor necrosis factor alpha, lcsh:Q, business, Transforming growth factor, Research Article
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5db78e5c4b3482b725e64c8f0973f880Test
http://europepmc.org/articles/PMC4226544?pdf=renderTest -
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المؤلفون: Miroslav Blumenberg
المصدر: PLoS ONE, Vol 9, Iss 9, p e102466 (2014)
PLoS ONEمصطلحات موضوعية: Cell signaling, Transcription, Genetic, Microarrays, Cancer Treatment, lcsh:Medicine, Signal transduction, Pharmacology, Biochemistry, Lung and Intrathoracic Tumors, Neoplasms, Molecular Cell Biology, Breast Tumors, Medicine and Health Sciences, Gene Regulatory Networks, Precision Medicine, lcsh:Science, Neurological Tumors, Oligonucleotide Array Sequence Analysis, EGFR inhibitors, Regulation of gene expression, Multidisciplinary, Kinase, Systems Biology, Neoplasm Proteins, Signal inhibition, ErbB Receptors, Gene Expression Regulation, Neoplastic, Drug Combinations, Bioassays and Physiological Analysis, Neurology, Oncology, Erlotinib, EGFR signaling, Research Article, medicine.drug, Cell biology, Immunology, Biological Data Management, Antineoplastic Agents, Biology, Research and Analysis Methods, Gefitinib, Antibody Therapy, medicine, Humans, Kinase activity, Protein Kinase Inhibitors, Transcription factor, Biology and life sciences, Gene Expression Profiling, lcsh:R, Computational Biology, Cancers and Neoplasms, Microarray Analysis, MicroRNAs, Cancer research, RNA, Clinical Immunology, lcsh:Q, Glioblastoma Multiforme
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a6d24bed8b05e99d52271e15b0c2b63Test
http://europepmc.org/articles/PMC4153546?pdf=renderTest -
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المؤلفون: Neelu Puri, Marie Nlend, Jason T. Fong, Gregory M. Botting, David N Moravec, Ryan J. Jacobs, Srijayaprakash B. Uppada
المصدر: PLoS ONE
PLoS ONE, Vol 8, Iss 11, p e78398 (2013)مصطلحات موضوعية: Indoles, Lung Neoplasms, lcsh:Medicine, Pharmacology, Tyrosine-kinase inhibitor, Piperazines, c-Met inhibitor, 0302 clinical medicine, Carcinoma, Non-Small-Cell Lung, lcsh:Science, Erlotinib Hydrochloride, EGFR inhibitors, 0303 health sciences, Sulfonamides, Multidisciplinary, Chemistry, TOR Serine-Threonine Kinases, Wnt signaling pathway, Drug Synergism, Proto-Oncogene Proteins c-met, 3. Good health, ErbB Receptors, Gene Expression Regulation, Neoplastic, 030220 oncology & carcinogenesis, Drug Therapy, Combination, Erlotinib, Tyrosine kinase, Heterocyclic Compounds, 3-Ring, medicine.drug, Research Article, Signal Transduction, medicine.drug_class, Antineoplastic Agents, 03 medical and health sciences, Cell Line, Tumor, medicine, Humans, Everolimus, Protein Kinase Inhibitors, 030304 developmental biology, Sirolimus, lcsh:R, respiratory tract diseases, Wnt Proteins, Drug Resistance, Neoplasm, Mutation, Quinazolines, lcsh:Q
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34763646651827c16b81bf00c3ef3defTest
http://europepmc.org/articles/PMC3817236Test