Cervical human papillomavirus infection in women with preterm prelabor rupture of membranes
| العنوان: | Cervical human papillomavirus infection in women with preterm prelabor rupture of membranes |
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| المؤلفون: | Petr Halada, Marian Kacerovsky, Adela Matejkova, Jan Laco, Hana Vošmiková, Ivana Musilova, Helena Hornychova, Radka Bolehovska, Helena Zemlickova, Petra Čermáková, Lenka Pliskova, Katerina Rozkosova, Bo Jacobsson |
| المصدر: | PLoS ONE, Vol 13, Iss 11, p e0207896 (2018) PLoS ONE |
| بيانات النشر: | Public Library of Science (PLoS), 2018. |
| سنة النشر: | 2018 |
| مصطلحات موضوعية: | Viral Diseases, Fetal Membranes, Premature Rupture, Amniotic fluid, Pulmonology, Physiology, Maternal Health, lcsh:Medicine, Cervix Uteri, Pathology and Laboratory Medicine, Patient Admission, 0302 clinical medicine, Pregnancy, Infant Mortality, Medicine and Health Sciences, Rupture of membranes, lcsh:Science, Immune Response, Papillomaviridae, 030219 obstetrics & reproductive medicine, Multidisciplinary, medicine.diagnostic_test, Obstetrics, HPV infection, Obstetrics and Gynecology, virus diseases, female genital diseases and pregnancy complications, Body Fluids, Hpv testing, Infectious Diseases, Medical Microbiology, Viral Pathogens, 030220 oncology & carcinogenesis, Viruses, Amniocentesis, Gestation, Female, Anatomy, Pathogens, Research Article, Adult, Human Papillomavirus Infection, medicine.medical_specialty, Papillomaviruses, Urology, Immunology, Sexually Transmitted Diseases, Microbiology, 03 medical and health sciences, Signs and Symptoms, Diagnostic Medicine, medicine, Humans, Human papillomavirus, Microbial Pathogens, Inflammation, Genitourinary Infections, Preterm Labor, business.industry, Papillomavirus Infections, lcsh:R, Organisms, Infant, Newborn, Biology and Life Sciences, Neonates, Human Papillomavirus, Infant, Amniotic Fluid, medicine.disease, Health Care, Neonatal outcomes, Respiratory Infections, Birth, Women's Health, lcsh:Q, Health Statistics, Morbidity, DNA viruses, business, Developmental Biology |
| الوصف: | Objective To evaluate the association between cervical human papillomavirus (HPV) infection at the time of admission and the presence of microbial invasion of the amniotic cavity (MIAC) and intra-amniotic inflammation (IAI) in women with preterm prelabor rupture of membranes (PPROM) and to determine the association between cervical HPV infection and short-term neonatal morbidity. Methods One hundred women with singleton pregnancies complicated by PPROM between the gestational ages of 24+0 and 36+6 weeks were included in the study. The presence of HPV DNA was evaluated in scraped cervical cells using polymerase chain reaction (PCR). Amniotic fluid samples were obtained by transabdominal amniocentesis. Results The rate of cervical HPV infection in women with PPROM was 24%. The rates of MIAC and IAI were not different between women with cervical HPV infection and those without cervical HPV infection [MIAC: with HPV: 21% (5/24) vs. without HPV: 22% (17/76), p = 1.00; IAI: with HPV: 21% (5/24) vs. without HPV: 18% (14/76), p = 0.77]. There were no differences in the selected aspects of short-term neonatal morbidity between women with and without cervical HPV infection. Conclusions In women with PPROM, the presence of cervical HPV infection at the time of admission is not related to a higher risk of intra-amniotic infection-related and inflammatory complications or worse short-term neonatal outcomes. |
| وصف الملف: | application/pdf |
| تدمد: | 1932-6203 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2abd1c7c6f01e2ae48fbe4966f2e7bfTest https://doi.org/10.1371/journal.pone.0207896Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....a2abd1c7c6f01e2ae48fbe4966f2e7bf |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 19326203 |
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