Sociodemographic Factors and Clinical Conditions Associated to Hospitalization in Influenza A (H1N1) 2009 Virus Infected Patients in Spain, 2009–2010
| العنوان: | Sociodemographic Factors and Clinical Conditions Associated to Hospitalization in Influenza A (H1N1) 2009 Virus Infected Patients in Spain, 2009–2010 |
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| المؤلفون: | González-Candelas, Fernando, Astray, Jenaro, Alonso, Jordi, Castro, Ady, Cantón, Rafael, Galán, Juan Carlos, Garín, Olatz, Sáez, Marc, Soldevila, Núria, Baricot, Maretva, Castilla, Jesús, Godoy i García, Pere, Delgado-Rodríguez, Miguel, Martín, Vicente, Mayoral, José María, Pumarola, Tomás, Quintana, José María, Tamames, Sonia, Domínguez García, Àngela, CIBERESP Cases and Controls in Pandemic Influenza Working Group |
| المساهمون: | CIBERESP Cases and Controls in Pandemic Influenza Working Group', [González-Candelas,F] Unidad Mixta Genómica y Salud CSISP-Universitat de València, Valencia, Spain. [González-Candelas,F, Alonso,J, Cantón,R, Galán,JC, Garin,O, Sáez,M, Soldevila,N, Baricot,M, Castilla,J, Godoy,P, Delgado-Rodríguez,M, Martín,V, Quintana,JM, Domínguez,A] CIBER Epidemiología y Salud Pública, Madrid, Spain. [Astray,J] Subdirección de Vigilancia, Comunidad de Madrid, Madrid, Spain. [Alonso,J] Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, Barcelona, Spain. [Alonso,J, Garin,O] Unitat de Recerca en Serveis Sanitaris, Institut Municipal d’Investigació Mèdica-Institut de Recerca de l’Hospital del Mar, Barcelona, Spain. [Castro,A] CIBER Enfermedades Respiratorias, Madrid, Spain. [Cantón,R, Galán,JC] Servicio de Microbiología, Hospital Universitario Ramón y Cajal, Madrid, Spain. [Sáez,M] Departament d’Economia, Universitat de Girona, Girona, Spain. [Castilla,J] Instituto de Salud Pública de Navarra, Pamplona, Spain. [Godoy,P] Departament de Salut, Generalitat de Catalunya, Barcelona, Spain. [Delgado-Rodríguez,M] División de Medicina Preventiva y Salud Pública, Universidad de Jaén, Jaén, Spain. [Martín,V] Instituto de Biomedicina, Universidad de León, León, Spain. [Mayoral,JM] Servicio de Vigilancia de Andalucía, Sevilla, Spain. [Pumarola,T] Red Española de Investigación en Patologías Infecciosas (REIPI), Madrid, Spain. [Quintana,JM] Fundación Vasca de Innovación e Investigación Sanitarias, Sondika, Spain. [Tamames,S] Dirección General de Salud Pública, Desarrollo e Innovación, Junta de Castilla y León, Valladolid, Spain. [Domínguez,A] Departament de Salut Pública, Universitat de Barcelona, Barcelona, Spain, Funding was provided by project GR09/0030 of the Instituto de Salud Carlos III/Ministerio de Ciencia e Innovación, Spain., Universitat de Barcelona |
| المصدر: | PLoS ONE Vol. 7 Issue 3 RODERIC. Repositorio Institucional de la Universitat de Valéncia instname Repositorio Abierto de la UdL Universitad de Lleida PLoS ONE, Vol 7, Iss 3, p e33139 (2012) Recercat. Dipósit de la Recerca de Catalunya PLoS ONE PLoS ONE, 2012, vol. 7, núm. 3, p. e33139 Articles publicats (D-EC) DUGiDocs – Universitat de Girona Dipòsit Digital de la UB Universidad de Barcelona |
| بيانات النشر: | Public Library of Science (PLoS), 2012. |
| سنة النشر: | 2012 |
| مصطلحات موضوعية: | Male, Viral Diseases, Pediatrics, Non-Clinical Medicine, Pulmonology, Epidemiology, Named Groups::Persons::Age Groups::Adult::Aged::Aged, 80 and over [Medical Subject Headings], Grip A (H1N1), Named Groups::Persons::Age Groups::Adult::Middle Aged [Medical Subject Headings], Disease, Social and Behavioral Sciences, medicine.disease_cause, Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Probability::Risk::Risk Factors [Medical Subject Headings], Hospital patients, Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings], Influenza A Virus, H1N1 Subtype, Gripe humana, Sociology, Risk Factors, Pandemic, Influenza A virus, Child, Aged, 80 and over, Geographicals::Geographic Locations::Europe::Spain [Medical Subject Headings], Organisms::Viruses::Vertebrate Viruses::RNA Viruses::Orthomyxoviridae::Influenzavirus A::Influenza A virus::Influenza A Virus, H1N1 Subtype [Medical Subject Headings], COPD, education.field_of_study, Multidisciplinary, Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Case-Control Studies [Medical Subject Headings], Named Groups::Persons::Age Groups::Child::Child, Preschool [Medical Subject Headings], Middle Aged, Hospitalization, Infectious Diseases, Analytical, Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Patient Care::Hospitalization [Medical Subject Headings], Child, Preschool, Named Groups::Persons::Age Groups::Adolescent [Medical Subject Headings], Medicine, Female, Public Health, Named Groups::Persons::Age Groups::Infant [Medical Subject Headings], Assistència hospitalària, Research Article, Adult, medicine.medical_specialty, Adolescent, Named Groups::Persons::Age Groups::Adult::Young Adult [Medical Subject Headings], Science, Population, Hospitals -- Pacients, Check Tags::Male [Medical Subject Headings], Named Groups::Persons::Age Groups::Infant::Infant, Newborn [Medical Subject Headings], Influenzavirus, Virus, Young Adult, Influenza, Human, Subtipo H1N1 del Virus de la Influenza A, Named Groups::Persons::Age Groups::Adult [Medical Subject Headings], medicine, Influenza viruses, Humans, Epidemiologia -- Investigació -- Espanya, Espanya, Epidemiologia, education, Pandemics, Biology, Named Groups::Persons::Age Groups::Child [Medical Subject Headings], Aged, Hospital care, Population Biology, business.industry, Public health, Infant, Newborn, Case-control study, Infant, Health Care::Environment and Public Health::Public Health::Disease Outbreaks::Epidemics::Pandemics [Medical Subject Headings], medicine.disease, Check Tags::Female [Medical Subject Headings], Spain, Case-Control Studies, H1N1 influenza, Diseases::Virus Diseases::RNA Virus Infections::Orthomyxoviridae Infections::Influenza, Human [Medical Subject Headings], business |
| الوصف: | The emergence and pandemic spread of a new strain of influenza A (H1N1) virus in 2009 resulted in a serious alarm in clinical and public health services all over the world. One distinguishing feature of this new influenza pandemic was the different profile of hospitalized patients compared to those from traditional seasonal influenza infections. Our goal was to analyze sociodemographic and clinical factors associated to hospitalization following infection by influenza A(H1N1) virus. We report the results of a Spanish nationwide study with laboratory confirmed infection by the new pandemic virus in a case-control design based on hospitalized patients. The main risk factors for hospitalization of influenza A (H1N1) 2009 were determined to be obesity (BMI≥40, with an odds-ratio [OR] 14.27), hematological neoplasia (OR 10.71), chronic heart disease, COPD (OR 5.16) and neurological disease, among the clinical conditions, whereas low education level and some ethnic backgrounds (Gypsies and Amerinds) were the sociodemographic variables found associated to hospitalization. The presence of any clinical condition of moderate risk almost triples the risk of hospitalization (OR 2.88) and high risk conditions raise this value markedly (OR 6.43). The risk of hospitalization increased proportionally when for two (OR 2.08) or for three or more (OR 4.86) risk factors were simultaneously present in the same patient. These findings should be considered when a new influenza virus appears in the human population. Funding was provided by project GR09/0030 of the Instituto de Salud Carlos III/Ministerio de Ciencia e Innovación, Spain. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript |
| وصف الملف: | application/pdf |
| تدمد: | 1932-6203 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52bc101221cd3c701041a223b73c98a5Test https://doi.org/10.1371/journal.pone.0033139Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....52bc101221cd3c701041a223b73c98a5 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 19326203 |
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