نتائج البحث - "genetic processes"

1

Detection of cooperatively bound transcription factor pairs using ChIP-seq peak intensities and expectation maximization

المؤلفون: Sandeep Krishna, Vishaka Datta, Rahul Siddharthan

المصدر: PLoS ONE
PLoS ONE, Vol 13, Iss 7, p e0199771 (2018)

مصطلحات موضوعية: 0301 basic medicine, genetic structures, genetic processes, lcsh:Medicine, Gene Expression, Yeast and Fungal Models, Plasma protein binding, Biochemistry, chemistry.chemical_compound, Database and Informatics Methods, Mice, Protein Interaction Mapping, lcsh:Science, Physics, Genetics, Multidisciplinary, Applied Mathematics, Simulation and Modeling, Drosophila Melanogaster, Eukaryota, Animal Models, Insects, Experimental Organism Systems, Physical Sciences, Drosophila, Sequence Analysis, Algorithms, Research Article, Protein Binding, Chromatin Immunoprecipitation, Arthropoda, Bioinformatics, Saccharomyces cerevisiae, DNA transcription, Genomics, Computational biology, Biology, Research and Analysis Methods, 03 medical and health sciences, Saccharomyces, Model Organisms, Sequence Motif Analysis, Expectation–maximization algorithm, DNA-binding proteins, Escherichia coli, Animals, natural sciences, Gene Regulation, Enhancer, Transcription factor, Sequence (medicine), lcsh:R, Organisms, Fungi, Cooperative binding, Biology and Life Sciences, Proteins, Promoter, biology.organism_classification, Invertebrates, Yeast, Regulatory Proteins, 030104 developmental biology, chemistry, lcsh:Q, DNA, Mathematics, Software, Transcription Factors

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53dc51e63ed83ee4e8705a7d841e34b8Test
http://europepmc.org/articles/PMC6049898Test

2

Comparative analysis of the end-joining activity of several DNA ligases

المؤلفون: Robert J. Bauer, Larry A. McReynolds, Katharina Bilotti, Thomas C. Evans, Alexander M. Zhelkovsky, Gregory J. S. Lohman, Laura E. Crowell

المصدر: PLoS ONE, Vol 12, Iss 12, p e0190062 (2017)
PLoS ONE

مصطلحات موضوعية: 0301 basic medicine, Gel electrophoresis of nucleic acids, Molecular biology, genetic processes, Electrophoretic techniques, DNA electrophoresis, lcsh:Medicine, Biochemistry, Ligases, chemistry.chemical_compound, Sticky and blunt ends, Nucleic Acids, DNA Breaks, Double-Stranded, Ligation Assay, lcsh:Science, chemistry.chemical_classification, Multidisciplinary, Blunt-End Ligation, Physics, Condensed Matter Physics, Enzymes, Physical Sciences, Research Article, DNA Ligases, Materials Science, Material Properties, DNA construction, DNA-binding protein, 03 medical and health sciences, DNA-binding proteins, Genetics, Humans, Molecular Biology Assays and Analysis Techniques, DNA ligase, DNA manipulations, DNA fragment ligation, lcsh:R, Electrophoresis, Capillary, Biology and Life Sciences, Proteins, DNA, DNA-binding domain, Research and analysis methods, enzymes and coenzymes (carbohydrates), Molecular biology techniques, 030104 developmental biology, chemistry, Enzymology, Anisotropy, lcsh:Q, Ligation

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::578297f0e3800e4ec08e417d66e5030aTest
http://europepmc.org/articles/PMC5746248?pdf=renderTest

3

Roles of C-Terminal Region of Yeast and Human Rad52 in Rad51-Nucleoprotein Filament Formation and ssDNA Annealing

المؤلفون: Tomohiko Sugiyama, Nilesh V. Khade

المصدر: PLoS ONE, Vol 11, Iss 6, p e0158436 (2016)
PLoS ONE

مصطلحات موضوعية: Glycerol, 0301 basic medicine, viruses, RAD52, genetic processes, RAD51, lcsh:Medicine, Yeast and Fungal Models, Artificial Gene Amplification and Extension, DNA annealing, Biochemistry, Polymerase Chain Reaction, chemistry.chemical_compound, 0302 clinical medicine, Medicine and Health Sciences, lcsh:Science, Base Pairing, Recombination, Genetic, Multidisciplinary, biology, Physics, Physical sciences, Nucleic acids, Chemistry, 030220 oncology & carcinogenesis, Nucleic acid thermodynamics, Protein Binding, Research Article, Saccharomyces cerevisiae Proteins, DNA recombination, Base pair, Annealing (genetics), Saccharomyces cerevisiae, Biophysics, DNA, Single-Stranded, Monomers (Chemistry), Research and Analysis Methods, Saccharomyces, 03 medical and health sciences, Model Organisms, Single-Strand Annealing, DNA-binding proteins, Genetics, Humans, Protein Interaction Domains and Motifs, Polymer chemistry, Binding site, Molecular Biology Techniques, Molecular Biology, Replication protein A, Binding Sites, Biology and life sciences, lcsh:R, Organisms, Fungi, Recombinational DNA Repair, Proteins, DNA, biology.organism_classification, Molecular biology, Yeast, Rad52 DNA Repair and Recombination Protein, Health Care, DNA binding site, enzymes and coenzymes (carbohydrates), Nucleoproteins, 030104 developmental biology, chemistry, health occupations, lcsh:Q, Rad51 Recombinase, Protein Multimerization

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8f898c7fb71273fd7415902af6fdf06Test
http://europepmc.org/articles/PMC4928909?pdf=renderTest

4

BRCA1 and CtIP Are Both Required to Recruit Dna2 at Double-Strand Breaks in Homologous Recombination

المؤلفون: Junya Kobayashi, Mayumi Hirakawa, Tanya T. Paull, Shunichi Takeda, Hiroyuki Sasanuma, Masato Omura, Nguyen Ngoc Hoa, Kenshi Komatsu, Soo Hyun Yang

المصدر: PLoS ONE
PLoS ONE, Vol 10, Iss 4, p e0124495 (2015)

مصطلحات موضوعية: Cell cycle checkpoint, Immunoprecipitation, Science, Saccharomyces cerevisiae, genetic processes, Biology, medicine.disease_cause, Cell Line, chemistry.chemical_compound, medicine, Animals, Humans, DNA Breaks, Double-Stranded, Gene Knock-In Techniques, Nuclear protein, Homologous Recombination, Chromosome Aberrations, Mutation, Nuclease, Multidisciplinary, Binding Sites, Endodeoxyribonucleases, BRCA1 Protein, fungi, DNA Helicases, Nuclear Proteins, Epistasis, Genetic, Cell Cycle Checkpoints, biology.organism_classification, Molecular biology, Cell biology, Enzyme Activation, enzymes and coenzymes (carbohydrates), Protein Transport, chemistry, biology.protein, health occupations, Medicine, Rad51 Recombinase, biological phenomena, cell phenomena, and immunity, Homologous recombination, Carrier Proteins, Chickens, DNA, Protein Binding, Research Article

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e891c23d60c0edca2ece68ea681ebc3eTest
https://pubmed.ncbi.nlm.nih.gov/25909997Test

5

Structural and Functional Characterization of the Redβ Recombinase from Bacteriophage λ

المؤلفون: Ali D. Malay, Fiona Curtis, Kazuko Matsubara, Gary J. Sharples, Jonathan G. Heddle

المصدر: PLoS ONE
PLoS ONE, Vol 8, Iss 11, p e78869 (2013)
PLoS ONE, 2013, Vol.8(11), pp.e78869 [Peer Reviewed Journal]

مصطلحات موضوعية: DNA recombination, RAD52, genetic processes, lcsh:Medicine, DNA, Single-Stranded, Sequence alignment, DNA annealing, Transmission electron microscopy, Bacteriophage, Recombinases, chemistry.chemical_compound, Structure-Activity Relationship, Viral Proteins, Protein structure, DNA-binding proteins, Recombinase, Bacteriophages, Homologous recombination, lcsh:Science, Protein Structure, Quaternary, Recombinant proteins, Genetics, Multidisciplinary, biology, Chemistry, lcsh:R, biology.organism_classification, Bacteriophage lambda, Protein Structure, Tertiary, enzymes and coenzymes (carbohydrates), DNA, Viral, Biophysics, lcsh:Q, Protein quaternary structure, DNA, Research Article

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c231d123f2fd1d3d942fbfdbadd0834Test
http://europepmc.org/articles/PMC3823998Test

6

MutS Homologue hMSH5: Recombinational DSB Repair and Non-Synonymous Polymorphic Variants

المؤلفون: Katey Feng, Xiling Wu, Chengtao Her, Joshua D. Tompkins, Yang Xu

المصدر: PLoS ONE
PLoS ONE, Vol 8, Iss 9, p e73284 (2013)

مصطلحات موضوعية: DNA Repair, genetic processes, Cancer Treatment, lcsh:Medicine, Cell Cycle Proteins, Biochemistry, law.invention, chemistry.chemical_compound, Oxidative Damage, 0302 clinical medicine, MRE11 Homologue Protein, law, Molecular Cell Biology, Basic Cancer Research, DNA Breaks, Double-Stranded, lcsh:Science, Homologous Recombination, 0303 health sciences, Multidisciplinary, Genomics, Chromatin, 3. Good health, Cell biology, Nucleic acids, DNA-Binding Proteins, Oncology, 030220 oncology & carcinogenesis, Recombinant DNA, Medicine, biological phenomena, cell phenomena, and immunity, medicine.drug, Research Article, DNA damage, DNA repair, Cell Survival, Antineoplastic Agents, Biology, 03 medical and health sciences, medicine, Genetics, Humans, 030304 developmental biology, Cisplatin, Polymorphism, Genetic, lcsh:R, fungi, Radiobiology, DNA, Molecular biology, enzymes and coenzymes (carbohydrates), HEK293 Cells, chemistry, Mutation, lcsh:Q, Rad51 Recombinase, Homologous recombination

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::816bf5f3e8499eeab9a3c6d2e9890a53Test
http://europepmc.org/articles/PMC3762724Test

7

Coordinated Binding of Single-Stranded and Double-Stranded DNA by UvsX Recombinase

المؤلفون: Robyn L. Maher, Scott W. Morrical

المصدر: PLoS ONE
PLoS ONE, Vol 8, Iss 6, p e66654 (2013)

مصطلحات موضوعية: DNA repair, DNA recombination, genetic processes, RAD51, Biophysics, lcsh:Medicine, DNA, Single-Stranded, Biology, DNA replication, Biochemistry, Fluorescence, 03 medical and health sciences, chemistry.chemical_compound, Viral Proteins, Adenosine Triphosphate, Recombinase, Binding site, lcsh:Science, 030304 developmental biology, Enzyme Kinetics, 0303 health sciences, Multidisciplinary, Binding Sites, Oligonucleotide, lcsh:R, 030302 biochemistry & molecular biology, Proteins, Membrane Proteins, DNA, Molecular biology, Enzymes, DNA binding site, Nucleic acids, DNA-Binding Proteins, enzymes and coenzymes (carbohydrates), chemistry, health occupations, Biocatalysis, lcsh:Q, Homologous recombination, Research Article

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa3203376aed5788cbbef4d971bb850bTest
http://europepmc.org/articles/PMC3688935Test

8

Identification of a Small Molecule Inhibitor of RAD52 by Structure-Based Selection

المؤلفون: Wayne E. Childers, Tomasz Skorski, Robert Hromas, Daniel L. McElroy, David A. Ostrov, Katherine J. Sullivan, Kimberly Cramer-Morales, Kimberly Haas

المصدر: PLoS ONE, Vol 11, Iss 1, p e0147230 (2016)
PLoS ONE

مصطلحات موضوعية: Models, Molecular, 0301 basic medicine, Ribonucleotide, Protein Conformation, genetic processes, lcsh:Medicine, Synthetic lethality, chemistry.chemical_compound, Computational Chemistry, Medicine and Health Sciences, Tumor Cells, Cultured, Drug Interactions, lcsh:Science, Crystallography, Multidisciplinary, Organic Compounds, Pharmaceutics, BRCA1 Protein, Physics, Condensed Matter Physics, Small molecule, Molecular Docking, 3. Good health, Molecular Docking Simulation, Chemistry, Physical Sciences, Crystal Structure, Chemical characterization, Female, Cell Binding Assay, Research Article, Biotechnology, Drug Synthesis, DNA repair, DNA, Single-Stranded, Breast Neoplasms, Library Screening, DNA binding assay, Biology, Research and Analysis Methods, Small Molecule Libraries, 03 medical and health sciences, In vivo, Binding analysis, Solid State Physics, Humans, Molecular Biology Techniques, Molecular Biology, Germ-Line Mutation, Pharmacology, Molecular Biology Assays and Analysis Techniques, Pharmaceutical Processing Technology, Organic Chemistry, lcsh:R, Chemical Compounds, Biology and Life Sciences, DNA-binding domain, Molecular biology, Rad52 DNA Repair and Recombination Protein, 030104 developmental biology, chemistry, Small Molecules, lcsh:Q, Homologous recombination, DNA

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20a02b928f31fcb4be51199955f67660Test
https://doi.org/10.1371/journal.pone.0147230Test

9

The Mre11 nuclease is critical for the sensitivity of cells to Chk1 inhibition

المؤلفون: Alan Eastman, Ryan Montano, Ruth Thompson

المصدر: PLoS ONE
PLoS ONE, Vol 7, Iss 8, p e44021 (2012)

مصطلحات موضوعية: genetic processes, lcsh:Medicine, environment and public health, Biochemistry, chemistry.chemical_compound, 0302 clinical medicine, Molecular cell biology, MRE11 Homologue Protein, Drug Discovery, Basic Cancer Research, DNA Breaks, Double-Stranded, Phosphorylation, lcsh:Science, 0303 health sciences, Osteosarcoma, Multidisciplinary, biology, MUS81, 3. Good health, DNA-Binding Proteins, Nucleic acids, Oncology, 030220 oncology & carcinogenesis, Medicine, biological phenomena, cell phenomena, and immunity, Research Article, Biotechnology, Drugs and Devices, Drug Research and Development, DNA damage, DNA repair, Pyrimidinones, DNA replication, 03 medical and health sciences, Cell Line, Tumor, Humans, CHEK1, Biology, 030304 developmental biology, Nuclease, lcsh:R, Thiones, DNA, Molecular biology, enzymes and coenzymes (carbohydrates), Pyrimidines, chemistry, Rad50, Checkpoint Kinase 1, biology.protein, health occupations, Pyrazoles, lcsh:Q, Protein Kinases, DNA Damage

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::249491997a4c56308593a5048e028f36Test
https://pubmed.ncbi.nlm.nih.gov/22937147Test

10

Connecting mutations of the RNA polymerase II C-terminal domain to complex phenotypic changes using combined gene expression and network analyses

المؤلفون: John W. Stiller, Carlyle Rogers, Zhen-Hua Guo

المصدر: PLoS ONE, Vol 5, Iss 6, p e11386 (2010)
PLoS ONE

مصطلحات موضوعية: Mutant, genetic processes, Gene Expression, lcsh:Medicine, RNA polymerase II, Cell Separation, medicine.disease_cause, environment and public health, Molecular Biology/Bioinformatics, chemistry.chemical_compound, 0302 clinical medicine, Gene expression, DNA, Fungal, lcsh:Science, Oligonucleotide Array Sequence Analysis, Genetics, 0303 health sciences, Mutation, Multidisciplinary, Genetics and Genomics/Gene Expression, Genetics and Genomics/Bioinformatics, Flow Cytometry, RNA Polymerase II, Chromosomes, Fungal, Research Article, Molecular Sequence Data, Saccharomyces cerevisiae, Computational biology, Biology, 03 medical and health sciences, medicine, Amino Acid Sequence, Molecular Biology, Gene, Cell Biology/Gene Expression, 030304 developmental biology, fungi, lcsh:R, Genetics and Genomics, Cell Biology, biology.organism_classification, enzymes and coenzymes (carbohydrates), chemistry, biology.protein, health occupations, lcsh:Q, CTD, 030217 neurology & neurosurgery, DNA

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c177b4713bc0b6ac822cf0ebf01c59c3Test
http://europepmc.org/articles/PMC2894937?pdf=renderTest

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