نتائج البحث - "Sequestosome-1"

1

The SQSTM1-NUP214 fusion protein interacts with Crm1, activates Hoxa and Meis1 genes, and drives leukemogenesis in mice

المؤلفون: Sei-Gyung K. Sze, Catherine Lavau, Sarah A. Port, Ralph H. Kehlenbach, Waitman K. Aumann, Veerain Gupta, Daniel S. Wechsler, Katelyn Ripple

المصدر: PLoS ONE
PLoS ONE, Vol 15, Iss 4, p e0232036 (2020)

مصطلحات موضوعية: 0301 basic medicine, Oncogene Proteins, Fusion, Amino Acid Motifs, Receptors, Cytoplasmic and Nuclear, medicine.disease_cause, Biochemistry, Hematologic Cancers and Related Disorders, Cell Fusion, Mice, 0302 clinical medicine, Animal Cells, Sequestosome-1 Protein, Medicine and Health Sciences, Blood and Lymphatic System Procedures, Myeloid Ecotropic Viral Integration Site 1 Protein, Bone Marrow Transplantation, Regulation of gene expression, Mutation, Leukemia, Multidisciplinary, Cell fusion, Myeloid leukemia, Hematology, Up-Regulation, Cell biology, Gene Expression Regulation, Neoplastic, Oncology, 030220 oncology & carcinogenesis, Medicine, Cellular Types, Research Article, Cell Physiology, Science, Bone Marrow Cells, Surgical and Invasive Medical Procedures, Karyopherins, Biology, DNA-binding protein, Cell Line, Digestive System Procedures, 03 medical and health sciences, Protein Domains, Leukemias, DNA-binding proteins, medicine, Animals, Point Mutation, Homeobox, Protein Interactions, Nuclear export signal, Homeodomain Proteins, Transplantation, Cancers and Neoplasms, Biology and Life Sciences, Proteins, Cell Biology, Organ Transplantation, Fusion protein, Liver Transplantation, Nuclear Pore Complex Proteins, 030104 developmental biology, Mutagenesis, Site-Directed, Chromatin immunoprecipitation, Neoplasm Transplantation

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e8aa6b22865b99e13ad03bd5d63c6c8Test
https://doi.org/10.1371/journal.pone.0232036Test

2

Autophagy mediates epithelial cancer chemoresistance by reducing p62/SQSTM1 accumulation

المؤلفون: R Alessia Battista, Leone Giordano, Mario Bussi, Francesca Paradiso, Enrico Milan, Elena Ruggieri, Floriana Cremasco, Massimo Resnati, Simone Cenci, Cecilia Facchi, Ugo Orfanelli

المساهمون: Alessia Battista, R., Resnati, M., Facchi, C., Ruggieri, E., Cremasco, F., Paradiso, F., Orfanelli, U., Giordano, L., Bussi, M., Cenci, S., Milan, E.

المصدر: PLoS ONE
PLoS ONE, Vol 13, Iss 8, p e0201621 (2018)

مصطلحات موضوعية: 0301 basic medicine, lcsh:Medicine, Gene Expression, Docetaxel, medicine.disease_cause, Biochemistry, Antioxidants, Ubiquitin, Sequestosome-1 Protein, Medicine and Health Sciences, Enzyme assays, Neoplasms, Glandular and Epithelial, Colorimetric assays, lcsh:Science, Bioassays and physiological analysis, Chemotherapeutic Agents, Cellular Stress Responses, chemistry.chemical_classification, Multidisciplinary, MTT assay, Cell Death, Pharmaceutics, Drugs, Gene Expression Regulation, Neoplastic, Oncology, Cell Processes, Oncology Agents, Fluorouracil, medicine.drug, Research Article, Autophagic Cell Death, Down-Regulation, Antineoplastic Agents, Biology, 03 medical and health sciences, Downregulation and upregulation, Protein Domains, Drug Therapy, Cell Line, Tumor, medicine, Autophagy, Genetics, Humans, Cisplatin, Pharmacology, Reactive oxygen species, lcsh:R, Biology and Life Sciences, Cell Biology, Research and analysis methods, Oxidative Stress, 030104 developmental biology, chemistry, Cell culture, Drug Resistance, Neoplasm, Cancer cell, Mutation, Biochemical analysis, biology.protein, Cancer research, lcsh:Q, Oxidative stress

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bcbcf4e22c70bdb560572e11a221bdcTest
https://pubmed.ncbi.nlm.nih.gov/30067838Test

3

Molecular effect of an OPTN common variant associated to Paget's disease of bone

المؤلفون: Iris A.L. Silva, M. Leonor Cancela, Edith Gagnon, Laëtitia Michou, Natércia Conceição, Jacques P. Brown

المصدر: PLoS ONE, Vol 13, Iss 5, p e0197543 (2018)
PLoS ONE
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP

مصطلحات موضوعية: 0301 basic medicine, Identification, Candidate gene, Heredity, Transcription Factor, Physiology, Protein Data Bank (RCSB PDB), Osteoclasts, lcsh:Medicine, Cell Cycle Proteins, Biochemistry, Animal Cells, Transcription Factor TFIIIA, Sequestosome-1 Protein, Medicine and Health Sciences, lcsh:Science, Connective Tissue Cells, Optineurin, Genetics, education.field_of_study, DNA methylation, Multidisciplinary, Genetic-Heterogeneity, Chromosome 18Q, Cell Death, Linkage, NF-kappa B, Cell Differentiation, Chromatin, Up-Regulation, Nucleic acids, Genetic Mapping, Connective Tissue, Cell Processes, Epigenetics, Bone Remodeling, Anatomy, Cellular Types, DNA modification, Autophagy Receptor, Chromatin modification, Research Article, Chromosome biology, Locus, Autophagic Cell Death, Active Transport, Cell Nucleus, information science, Variant Genotypes, Locus (genetics), macromolecular substances, Biology, Polymorphism, Single Nucleotide, Cell Line, 03 medical and health sciences, Sequestosome 1, Autophagy, medicine, Humans, Genetic Predisposition to Disease, natural sciences, Bone Resorption, Allele, Bone, education, Gene, Alleles, Genetic Association Studies, lcsh:R, Biology and Life Sciences, Genetic Variation, Membrane Transport Proteins, Kappa-B Activation, Cell Biology, DNA, Binding, Osteitis Deformans, medicine.disease, Introns, Biological Tissue, 030104 developmental biology, Paget's disease of bone, Haplotypes, Genetic Loci, Mutation, health occupations, lcsh:Q, Gene expression, Physiological Processes