التفاصيل البيبلوغرافية
| العنوان: |
Tracheostomy and long-term mortality in ICU patients undergoing prolonged mechanical ventilation. |
| المؤلفون: |
Cinotti, Raphaël1 raphael.cinotti@chu-nantes.fr, Voicu, Sebastian2, Jaber, Samir3, Chousterman, Benjamin4,5, Paugam-Burtz, Catherine6, Oueslati, Haikel7, Damoisel, Charles5, Caillard, Anaïs4,5, Roquilly, Antoine1,8, Feuillet, Fanny9, Mebazaa, Alexandre4,5, Gayat, Etienne4,5, null, null |
| المصدر: |
PLoS ONE. 10/1/2019, Vol. 14 Issue 10, p1-12. 12p. |
| مصطلحات موضوعية: |
*INTENSIVE care units, *TRACHEOTOMY, *HEALTH facilities, *ADULT respiratory distress syndrome |
| مصطلحات جغرافية: |
BELGIUM, FRANCE |
| مستخلص: |
Introduction: In critically ill patients undergoing prolonged mechanical ventilation (MV), the difference in long-term outcomes between patients with or without tracheostomy remains unexplored. Methods: Ancillary study of a prospective international multicentre observational cohort in 21 centres in France and Belgium, including 2087 patients, with a one-year follow-up after admission. We included patients with a MV duration ≥10 days, with or without tracheostomy. We explored the one-year mortality with a classical Cox regression model (adjustment on age, SAPS II, baseline diagnosis and withdrawal of life-sustaining therapies) and a Cox regression model using tracheostomy as a time-dependant variable. Results: 29.5% patients underwent prolonged MV, out of which 25.6% received tracheostomy and 74.4% did not. At one-year, 45.2% patients had died in the tracheostomy group and 51.5% patients had died in the group without tracheostomy (p = 0.001). In the Cox-adjusted regression model, tracheostomy was not associated with improved one-year outcome (HR CI95 0.7 [0.5–1.001], p = 0.051), as well as in the model using tracheostomy as a time-dependent variable (OR CI 95 1 [0.7–1.4], p = 0.9). Conclusions: In our study, there was no statistically significant difference in the one-year mortality of patients undergoing prolonged MV when receiving tracheostomy or not. Trial registration: [ABSTRACT FROM AUTHOR] |
| قاعدة البيانات: |
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