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المؤلفون: James C. Reed, William M. Philbrick, Kevan C. Herold, Gabriel Betancur, Maria Korah, Paula Preston-Hurlburt, Carrie L. Lucas
المصدر: PLoS ONE
PLoS ONE, Vol 15, Iss 9, p e0236921 (2020)مصطلحات موضوعية: 0301 basic medicine, CD4-Positive T-Lymphocytes, Glycation End Products, Advanced, Male, endocrine system diseases, Receptor for Advanced Glycation End Products, ERK signaling cascade, CD8-Positive T-Lymphocytes, Jurkat cells, Biochemistry, RAGE (receptor), White Blood Cells, Jurkat Cells, 0302 clinical medicine, Endocrinology, Medical Conditions, Cell Signaling, Animal Cells, Medicine and Health Sciences, Cytotoxic T cell, Child, Staining, Multidisciplinary, Chemistry, T Cells, ZAP70, Signaling cascades, Cell Staining, Small interfering RNA, Nucleic acids, medicine.anatomical_structure, cardiovascular system, Medicine, Female, Signal transduction, Cellular Types, Research Article, Signal Transduction, Adult, Cell signaling, Adolescent, Endocrine Disorders, Science, T cell, Immune Cells, Immunology, Cytotoxic T cells, Research and Analysis Methods, Transfection, 03 medical and health sciences, Young Adult, medicine, Genetics, Diabetes Mellitus, Humans, cardiovascular diseases, Non-coding RNA, Molecular Biology Techniques, Molecular Biology, Inflammation, Blood Cells, nutritional and metabolic diseases, Biology and Life Sciences, Cell Biology, Gene regulation, 030104 developmental biology, Diabetes Mellitus, Type 1, Specimen Preparation and Treatment, Metabolic Disorders, Cancer research, RNA, Gene expression, human activities, CD8, 030215 immunology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1577b344dad8e8c8a4dd810bf63d920fTest
http://europepmc.org/articles/PMC7521722Test -
2Modulation of NCAM/FGFR1 signaling suppresses EMT program in human proximal tubular epithelial cells
المؤلفون: Björn Tampe, Gunsmaa Nyamsuren, Xingbo Xu, Maja Životić, Müller Ca, Aleksandar Lipkovski, Gerhard A. Müller, Jasmina Markovic-Lipkovski, Michael Zeisberg
المصدر: PLoS ONE
PLoS ONE, Vol 13, Iss 11, p e0206786 (2018)مصطلحات موضوعية: 0301 basic medicine, Cell signaling, Adhesion molecules, Kidneys, Fibrosis, Chronic kidney disease, Gene expression, Epithelial cells, Fibroblast growth factor, Signal initiation, Fibroblast Growth Factor, Physiology, lcsh:Medicine, Gene Expression, MMP9, Signal transduction, Fibroblast growth factor, CDH2, Epithelium, Kidney Tubules, Proximal, 0302 clinical medicine, Endocrinology, Animal Cells, Cell Movement, Chronic Kidney Disease, Medicine and Health Sciences, Protein Isoforms, lcsh:Science, Neural Cell Adhesion Molecules, Multidisciplinary, Cell adhesion molecule, Chemistry, Signaling cascades, Middle Aged, 3. Good health, Cell biology, Fibroblast growth factor receptor, Nephrology, 030220 oncology & carcinogenesis, Kidney Diseases, Anatomy, Cellular Types, Research Article, Adult, Epithelial-Mesenchymal Transition, Adhesion Molecules, Cell Line, Transforming Growth Factor beta1, 03 medical and health sciences, Growth Factors, Genetics, Humans, RNA, Messenger, Receptor, Fibroblast Growth Factor, Type 1, Smad3 Protein, Biology and life sciences, Endocrine Physiology, Fibroblast growth factor receptor 1, lcsh:R, Epithelial Cells, Renal System, Molecular Development, stomatognathic diseases, 030104 developmental biology, Biological Tissue, Pyrimidines, TGF-beta signaling cascade, SNAI1, lcsh:Q, Neural cell adhesion molecule, Snail Family Transcription Factors, Developmental Biology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75d72aa19abcedecfd6bf2355c9c2dbcTest
http://europepmc.org/articles/PMC6211750Test -
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المؤلفون: Sasia-Marie Jones, Biree Andemariam, Jing Zhang, George Lykotrafitis
المصدر: PLoS ONE
PLoS ONE, Vol 14, Iss 5, p e0216467 (2019)مصطلحات موضوعية: 0301 basic medicine, Male, Cell, Cell Membranes, 030204 cardiovascular system & hematology, Microscopy, Atomic Force, Biochemistry, Intracellular Receptors, Mice, 0302 clinical medicine, Catecholamines, Cell Signaling, Chlorocebus aethiops, Medicine and Health Sciences, Membrane Receptor Signaling, Amines, Receptor, Multidisciplinary, Chemistry, Organic Compounds, Neurotransmitter Receptor Signaling, Neurochemistry, Neurotransmitters, Hematology, 3. Good health, Spring, medicine.anatomical_structure, Epinephrine, Valsartan, Genetic Diseases, Physical Sciences, COS Cells, Medicine, Female, Seasons, Cellular Structures and Organelles, Intracellular, medicine.drug, Research Article, Signal Transduction, Adult, medicine.medical_specialty, Biogenic Amines, Transmembrane Receptors, Adolescent, Science, Erythrocytes, Abnormal, Receptor, Angiotensin, Type 1, Sickle Cell Trait, 03 medical and health sciences, Autosomal Recessive Diseases, Internal medicine, medicine, Animals, Humans, Clinical Genetics, Sickle cell trait, Sickle Cell Disease, Organic Chemistry, Erythrocyte Membrane, Chemical Compounds, Biology and Life Sciences, Proteins, Cell Biology, medicine.disease, Angiotensin II, Hormones, Hemoglobinopathies, Red blood cell, 030104 developmental biology, Endocrinology, HEK293 Cells, Earth Sciences, G Protein Coupled Receptors, Cell Adhesion Molecules, Neuroscience
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15c6a15af8ea5de99084afa21a8f2c1fTest
http://europepmc.org/articles/PMC6513067Test -
4Protein tyrosine phosphatase 1B as a therapeutic target for Graves’ orbitopathy in an in vitro model
المؤلفون: Jin Sook Yoon, Ji-Young Kim, Kikkawa Don, Jae Sang Ko, Eun Jig Lee, Hyeong Ju Byeon
المصدر: PLoS ONE, Vol 15, Iss 8, p e0237015 (2020)
PLoS ONEمصطلحات موضوعية: Male, 0301 basic medicine, Physiology, medicine.medical_treatment, Protein Expression, Apoptosis, Protein tyrosine phosphatase, Biochemistry, 0302 clinical medicine, Animal Cells, Immune Physiology, Medicine and Health Sciences, RNA, Small Interfering, Immune Response, Connective Tissue Cells, Protein Tyrosine Phosphatase, Non-Receptor Type 1, Innate Immune System, Multidisciplinary, Cell Death, Chemistry, Small interfering RNA, Middle Aged, Endoplasmic Reticulum Stress, Nucleic acids, Cytokine, Connective Tissue, Cell Processes, 030220 oncology & carcinogenesis, Cytokines, Medicine, Female, Tumor necrosis factor alpha, Cellular Types, Anatomy, Inflammation Mediators, Signal transduction, Research Article, Signal Transduction, Adult, Cell Survival, Science, Immunology, Prefrontal Cortex, In Vitro Techniques, Transfection, Research and Analysis Methods, Proinflammatory cytokine, 03 medical and health sciences, Signs and Symptoms, Gene Expression and Vector Techniques, Genetics, medicine, Animals, Humans, Gene Silencing, Molecular Biology Techniques, Non-coding RNA, Molecular Biology, Protein kinase B, Inflammation, Molecular Biology Assays and Analysis Techniques, Biology and Life Sciences, Cell Biology, Fibroblasts, Molecular Development, Fibrosis, Molecular biology, Gene regulation, Graves Ophthalmopathy, Oxidative Stress, Biological Tissue, 030104 developmental biology, Immune System, RNA, Cattle, Gene expression, PTPN1, Clinical Medicine, Reactive Oxygen Species, Developmental Biology, Transforming growth factor
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb4b11e7d3688c01d77bb19cda654a5aTest
https://doi.org/10.1371/journal.pone.0237015Test -
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المؤلفون: Russell P. Hall, Robert D. Streilein, Sravya M. Bhatia
المصدر: PLoS ONE
PLoS ONE, Vol 15, Iss 6, p e0233957 (2020)مصطلحات موضوعية: Male, 0301 basic medicine, Nicotinic Acetylcholine Receptors, Pathogenesis, Receptors, Nicotinic, Pathology and Laboratory Medicine, medicine.disease_cause, Biochemistry, Autoantigens, Steroid Therapy, 030207 dermatology & venereal diseases, 0302 clinical medicine, Prednisone, Iron-Binding Proteins, Medicine and Health Sciences, Enzyme-Linked Immunoassays, Multidisciplinary, Desmoglein 3, integumentary system, biology, Pharmaceutics, Organic Compounds, Desmoglein 1, Pemphigus Vulgaris, Middle Aged, Chemistry, Physical Sciences, Medicine, Steroids, Female, Rituximab, Research Article, Signal Transduction, medicine.drug, Adult, Patients, Transmembrane Receptors, Science, Immunology, Research and Analysis Methods, Iodide Peroxidase, Desmoglein, Autoimmune Diseases, Young Adult, 03 medical and health sciences, Drug Therapy, Thyroid peroxidase, medicine, Humans, Immunoassays, Aged, Autoantibodies, Retrospective Studies, Receptor, Muscarinic M3, business.industry, Organic Chemistry, Pemphigus vulgaris, Chemical Compounds, Autoantibody, Varicella zoster virus, Biology and Life Sciences, Proteins, Cell Biology, medicine.disease, Health Care, Pemphigus, 030104 developmental biology, Acetylcholine Receptors, Immunoglobulin G, Immunologic Techniques, biology.protein, Clinical Immunology, Clinical Medicine, business
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc243ae5ee4e87093bb165ce663b5453Test
https://doi.org/10.1371/journal.pone.0233957Test -
6Mechanism of anti-remodelling action of treprostinil in human pulmonary arterial smooth muscle cells
المؤلفون: Panja M. Boehm, Christoph Kornauth, Felicitas Oberndorfer, Walter Klepetko, Christopher Lambers, Michael Tamm, Michael Roth
المصدر: PLoS ONE
PLoS ONE, Vol 13, Iss 11, p e0205195 (2018)مصطلحات موضوعية: Male, Cell signaling, Physiology, Cell, Becaplermin, lcsh:Medicine, Prostacyclin, 030204 cardiovascular system & hematology, Pharmacology, Signal transduction, Biochemistry, Extracellular matrix, 0302 clinical medicine, Endocrinology, Cyclic AMP, Medicine and Health Sciences, Myocyte, Familial Primary Pulmonary Hypertension, Lipid Hormones, Pulmonary Arteries, lcsh:Science, Mitogen-Activated Protein Kinase 1, Multidisciplinary, biology, Chemistry, Signaling cascades, Arteries, Middle Aged, Extracellular Matrix, medicine.anatomical_structure, Female, Cellular Structures and Organelles, Anatomy, medicine.drug, Research Article, Adult, Collagen Type IV, Myocytes, Smooth Muscle, Pulmonary Artery, Vascular Remodeling, Collagen Type I, Transforming Growth Factor beta1, 03 medical and health sciences, Growth Factors, medicine, Humans, Secretion, Cell Proliferation, Endocrine Physiology, lcsh:R, Connective Tissue Growth Factor, Biology and Life Sciences, Proteins, Cell Biology, Epoprostenol, Hormones, Extracellular Matrix Composition, Fibronectins, CTGF, Fibronectin, 030228 respiratory system, Gene Expression Regulation, TGF-beta signaling cascade, biology.protein, CCAAT-Enhancer-Binding Proteins, Cardiovascular Anatomy, Blood Vessels, lcsh:Q, Physiological Processes, Collagens, Treprostinil
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4115f92933d2ee65ee174483bcd59e5Test
https://pubmed.ncbi.nlm.nih.gov/30383775Test -
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المؤلفون: Rainer Claus, Justus Duyster, Marcus Dühren-von-Minden, Christine Dierks, Kathrin Kläsener, Maike Buchner, Kerstin Leberecht, Hassan Jumaa, Fabio Malavasi, Marco Benkisser-Petersen, Arlette Dörffel, Hendrik Veelken, Meike Burger, Katja Zirlik, Michael Reth
المصدر: PLoS ONE, Vol 11, Iss 12, p e0169159 (2016)
PLoS One
PLoS ONE
PLoS ONE, 11(12)مصطلحات موضوعية: 0301 basic medicine, Male, Cell signaling, B Cells, R406 inhibited, Pyridines, Chronic lymphocytic leukemia, Syk, lcsh:Medicine, Apoptosis, CD38, Signal transduction, ERK signaling cascade, Biochemistry, Receptor tyrosine kinase, Hematologic Cancers and Related Disorders, White Blood Cells, 0302 clinical medicine, Spectrum Analysis Techniques, Animal Cells, Cell Movement, immune system diseases, hemic and lymphatic diseases, Medicine and Health Sciences, Tumor Cells, Cultured, SYK, Post-Translational Modification, Phosphorylation, Ligation Assay, Extracellular Signal-Regulated MAP Kinases, lcsh:Science, Chronic Lymphoblastic Leukemia, Aged, 80 and over, Multidisciplinary, Membrane Glycoproteins, biology, Cell Death, Chemistry, Signaling cascades, hemic and immune systems, Hematology, Middle Aged, Flow Cytometry, Cell Motility, Oncology, Spectrophotometry, Cell Processes, Lymphoblastic Leukemia, Female, Cytophotometry, Cellular Types, Research Article, Adult, Cell Survival, Immune Cells, Immunology, Cell Migration, Research and Analysis Methods, 03 medical and health sciences, Downregulation and upregulation, Leukemias, Oxazines, medicine, Humans, Syk Kinase, ddc:610, SYK, AKT, CD38, R406 inhibited, Antibody-Producing Cells, Molecular Biology Techniques, Protein kinase B, Molecular Biology, neoplasms, Aged, Molecular Biology Assays and Analysis Techniques, Blood Cells, AKT, lcsh:R, Cancers and Neoplasms, Biology and Life Sciences, Proteins, Cell Biology, medicine.disease, ADP-ribosyl Cyclase 1, Leukemia, Lymphocytic, Chronic, B-Cell, Chemokine CXCL12, 030104 developmental biology, biology.protein, Cancer research, Myeloid Cell Leukemia Sequence 1 Protein, lcsh:Q, Proto-Oncogene Proteins c-akt, 030215 immunology, Developmental Biology
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17d291812eb97c055e488c3b8b2968ddTest
http://europepmc.org/articles/PMC5201248?pdf=renderTest -
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المؤلفون: Jae Min Shin, Il Ho Park, Ju Hyung Kang, Heung Man Lee, Seoung Ae Lee
المصدر: PLoS ONE, Vol 11, Iss 12, p e0168195 (2016)
PLoS ONEمصطلحات موضوعية: Male, 0301 basic medicine, Cell signaling, Muscle Physiology, Physiology, Interleukin-1beta, Gene Expression, lcsh:Medicine, Signal transduction, Biochemistry, Extracellular matrix, chemistry.chemical_compound, 0302 clinical medicine, Animal Cells, Cell Movement, Medicine and Health Sciences, Enzyme assays, Colorimetric assays, Sulfones, lcsh:Science, Bioassays and physiological analysis, Cells, Cultured, Connective Tissue Cells, MTT assay, Multidisciplinary, biology, Chemistry, NF-kappa B, Signaling cascades, Cell Differentiation, Extracellular Matrix, Blot, Connective Tissue, 030220 oncology & carcinogenesis, Physical Sciences, Female, Collagen, Cellular Types, Anatomy, Cellular Structures and Organelles, Matrix Metalloproteinase 1, Mitogen-Activated Protein Kinases, Nasal Cavity, Myofibroblast, Research Article, Muscle Contraction, Bromides, Adult, MAPK signaling cascades, Inflammatory Diseases, Down-Regulation, Fibroblast migration, 03 medical and health sciences, Nitriles, Humans, Protein kinase B, Flavonoids, Migration Assay, lcsh:R, Chemical Compounds, Biology and Life Sciences, Proteins, Cell Biology, Fibroblasts, Molecular biology, Actins, Fibronectins, Research and analysis methods, Fibronectin, Biological Tissue, 030104 developmental biology, Biochemical analysis, biology.protein, lcsh:Q, Collagens, Proto-Oncogene Proteins c-akt, Baicalin
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0e6a513abb51e5e9a04ef15b864f4e8Test
http://europepmc.org/articles/PMC5176301?pdf=renderTest -
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المؤلفون: Soo-Kyoung Park, Sun-Hee Yeon, Jun Xu, Ruining Han, Ki-Sang Rha, Yong-De Jin, Yeong-Kyu Park, Yong Min Kim
المصدر: PLoS ONE
PLoS ONE, Vol 12, Iss 8, p e0181806 (2017)مصطلحات موضوعية: Male, Cell signaling, lcsh:Medicine, Artificial Gene Amplification and Extension, Signal transduction, ERK signaling cascade, Matrix metalloproteinase, Pathology and Laboratory Medicine, Biochemistry, Polymerase Chain Reaction, Extracellular matrix, 0302 clinical medicine, Cell Movement, Animal Cells, Medicine and Health Sciences, Small interfering RNAs, Nasal polyps, lcsh:Science, 030223 otorhinolaryngology, Immune Response, Connective Tissue Cells, Receptors, Interleukin-17, Multidisciplinary, biology, Chemistry, Interleukin-17, NF-kappa B, Signaling cascades, Cell Differentiation, Middle Aged, Nucleic acids, medicine.anatomical_structure, Connective Tissue, Female, Matrix Metalloproteinase 1, Mitogen-Activated Protein Kinases, Cellular Types, Anatomy, Myofibroblast, Research Article, Adult, MAPK signaling cascades, Immunology, Nose, Research and Analysis Methods, Gene Expression Regulation, Enzymologic, Fibroblast migration, 03 medical and health sciences, Nasal Polyps, Signs and Symptoms, Diagnostic Medicine, Matrix Metalloproteinase 13, Genetics, medicine, Humans, Vimentin, Sinusitis, Non-coding RNA, Molecular Biology Techniques, Fibroblast, Molecular Biology, Inflammation, lcsh:R, Biology and Life Sciences, Proteins, Receptors, Interleukin, Cell Biology, Reverse Transcriptase-Polymerase Chain Reaction, Fibroblasts, medicine.disease, Actins, Fibronectins, Gene regulation, Enzyme Activation, Fibronectin, Cytoskeletal Proteins, Biological Tissue, biology.protein, Cancer research, RNA, lcsh:Q, Gene expression, Collagens, 030215 immunology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3eba546929769b50d1b59c8dd39813f8Test
https://doi.org/10.1371/journal.pone.0181806Test