Correction: Surgical and regional treatments for colorectal cancer metastases in older patients: A systematic review and meta-analysis
| العنوان: | Correction: Surgical and regional treatments for colorectal cancer metastases in older patients: A systematic review and meta-analysis |
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| المؤلفون: | Florence Canuï-Poitrine, Daniele Sommacale, Thomas Aparicio, Alain Luciani, R. Brustia, Capucine Baldini, Evelyne Liuu, Elena Paillaud, Patrick Pessaux, Alexis Laurent, Vania Tacher, Bertrand Le Roy, Nicola de’Angelis, Hicham Kobeiter |
| المساهمون: | Institut de Recherche sur les Maladies Virales et Hépatiques (IVH), Université de Strasbourg (UNISTRA)-Institut National de la Santé et de la Recherche Médicale (INSERM), univOAK, Archive ouverte, Hôpital Henri Mondor, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Henri Mondor-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), Université Paris-Saclay, Institut Gustave Roussy (IGR), Département d’Innovation Thérapeutique et essais précoces [Gustave Roussy] (DITEP), CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Nouvel Hôpital Civil de Strasbourg, Hôpital Robert Debré, Hôpital Robert Debré-Centre Hospitalier Universitaire de Reims (CHU Reims), Université de Reims Champagne-Ardenne (URCA), CHU Saint-Etienne, Hôpital Européen Georges Pompidou [APHP] (HEGP), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO), Hopital Saint-Louis [AP-HP] (AP-HP), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Université Paris Diderot - Paris 7 (UPD7), Hôpital de la Milétrie, Centre hospitalier universitaire de Poitiers (CHU Poitiers) |
| المصدر: | PLoS ONE PLoS ONE, Public Library of Science, 2020, 15 (4), ⟨10.1371/journal.pone.0230914⟩ PLoS ONE, Vol 16, Iss 4, p e0251005 (2021) PLoS ONE, Vol 15, Iss 4, p e0230914 (2020) PLoS ONE, 2020, 15 (4), pp.e0230914. ⟨10.1371/journal.pone.0230914⟩ |
| بيانات النشر: | Public Library of Science (PLoS), 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | [SDV.MHEP.CHI] Life Sciences [q-bio]/Human health and pathology/Surgery, Colorectal cancer, Cancer Treatment, Psychological intervention, Metastasis, Postoperative Complications, 0302 clinical medicine, Basic Cancer Research, Medicine and Health Sciences, Medicine, Neoplasm Metastasis, Laparoscopy, Multidisciplinary, medicine.diagnostic_test, Hazard ratio, Age Factors, 3. Good health, Oncology, 030220 oncology & carcinogenesis, Meta-analysis, 030211 gastroenterology & hepatology, Colorectal Neoplasms, Research Article, Hepatic Resection, Risk, medicine.medical_specialty, Science, MEDLINE, [SDV.CAN]Life Sciences [q-bio]/Cancer, Surgical and Invasive Medical Procedures, [SDV.MHEP.CHI]Life Sciences [q-bio]/Human health and pathology/Surgery, Sciences du Vivant [q-bio]/Médecine humaine et pathologie, Digestive System Procedures, 03 medical and health sciences, [SDV.CAN] Life Sciences [q-bio]/Cancer, Internal medicine, Humans, Colorectal Cancer, Surgical Resection, business.industry, Cancers and Neoplasms, Correction, [SDV.MHEP.HEG]Life Sciences [q-bio]/Human health and pathology/Hépatology and Gastroenterology, medicine.disease, [SDV.MHEP.HEG] Life Sciences [q-bio]/Human health and pathology/Hépatology and Gastroenterology, digestive system diseases, Health Care, [SDV.SPEE] Life Sciences [q-bio]/Santé publique et épidémiologie, Relative risk, [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie, Health Statistics, Morbidity, business, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology |
| الوصف: | The present study explored the existing literature to describe the outcomes of surgical and regional treatments for colorectal cancer metastases (mCRC) in older patients. Methods A literature search was conducted in PubMed, EMBASE, Cochrane and ClinicalTrials.gov for studies published since 2000 that investigated the short- and long-term outcomes of regional treatments (surgical or non-surgical) for mCRC in patients aged ≥65 years. Pooled data analyses were conducted by calculating the risk ratio (RR), mean differences (MD) and hazard ratio (HR) between older and younger patients or between two different approaches in older patients. Results After screening 266 articles, 29 were included in this review. These studies reported the outcomes of surgery (n = 19) and non-surgical local ablation treatments (n = 3) for CRC metastases in older vs. younger patients or compared the outcomes of different interventions in older patients (n = 7). When comparing older vs. younger patients undergoing liver surgery for mCRC, pooled data analysis showed higher postoperative mortality [RR = 2.53 (95%CI: 2.00-3.21)] and shorter overall survival [HR = 1.17 (95%CI: 1.07-1.18)] in older patients, whereas no differences in operative outcomes, postoperative complications and disease-free survival were found. When comparing laparoscopy vs. open surgery for liver resection in older mCRC patients, laparoscopy was associated with fewer postoperative complications [RR = 0.27 (95%CI: 0.10-0.73)]. Conclusion Liver resection for mCRC should not be disregarded a priori in older patients, who show similar operative and postoperative outcomes as younger patients. However, clinicians should consider that they are at increased risk of postoperative mortality and have a worse overall survival, which may reflect comorbidities and frailty. journal article 2020 2020 04 22 imported |
| وصف الملف: | application/pdf |
| تدمد: | 1932-6203 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6799cce7ca9af029007b40bbd53307bTest https://doi.org/10.1371/journal.pone.0230914Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....b6799cce7ca9af029007b40bbd53307b |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 19326203 |
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