Thiol-based Oxidative Posttranslational Modifications (OxiPTMs) of Plant Proteins
| العنوان: | Thiol-based Oxidative Posttranslational Modifications (OxiPTMs) of Plant Proteins |
|---|---|
| المؤلفون: | Francisco J Corpas, Salvador González-Gordo, Marta Rodríguez-Ruiz, María A Muñoz-Vargas, José M Palma |
| المساهمون: | European Commission, Ministerio de Ciencia e Innovación (España), Junta de Andalucía |
| المصدر: | Plant and Cell Physiology. 63:889-900 |
| بيانات النشر: | Oxford University Press (OUP), 2022. |
| سنة النشر: | 2022 |
| مصطلحات موضوعية: | Physiology, S-glutathionylation, Cell Biology, Plant Science, General Medicine, S-nitrosation, Glutathione, Oxidative Stress, Persulfidation, Sulfhydryl Compounds, S-cyanylation and S-acylation, S-sulfenylation, Oxidation-Reduction, Protein Processing, Post-Translational, Plant Proteins |
| الوصف: | The thiol group of cysteine (Cys) residues, often present in the active center of the protein, is of particular importance to protein function, which is significantly determined by the redox state of a protein's environment. Our knowledge of different thiol-based oxidative posttranslational modifications (oxiPTMs), which compete for specific protein thiol groups, has increased over the last 10 years. The principal oxiPTMs include S-sulfenylation, S-glutathionylation, S-nitrosation, persulfidation, S-cyanylation and S-acylation. The role of each oxiPTM depends on the redox cellular state, which in turn depends on cellular homeostasis under either optimal or stressful conditions. Under such conditions, the metabolism of molecules such as glutathione, NADPH (reduced nicotinamide adenine dinucleotide phosphate), nitric oxide, hydrogen sulfide and hydrogen peroxide can be altered, exacerbated and, consequently, outside the cell's control. This review provides a broad overview of these oxiPTMs under physiological and unfavorable conditions, which can regulate the function of target proteins. European Regional Development Fund cofinanced grant from the Spanish Ministry of Science and Innovation (PID2019-103924GB-I00); Plan Andaluz de Investigacion, Desarrollo e Innovacion (PAIDI 2020) (P18-FR-1359); Junta de Andalucía (group BIO192), Spain to F.J.C. and J.M.P.. |
| تدمد: | 1471-9053 0032-0781 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3fd372d627fb03ec7e07a8c15a22a12Test https://doi.org/10.1093/pcp/pcac036Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....d3fd372d627fb03ec7e07a8c15a22a12 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14719053 00320781 |
|---|