التفاصيل البيبلوغرافية
| العنوان: |
Differences in visible light-induced pigmentation according to wavelengths: a clinical and histological study in comparison with UVB exposure. |
| المؤلفون: |
Duteil, Luc, Cardot ‐ Leccia, Nathalie, Queille ‐ Roussel, Catherine, Maubert, Yves, Harmelin, Yona, Boukari, Fériel, Ambrosetti, Damien, Lacour, Jean ‐ Philippe, Passeron, Thierry |
| المصدر: |
Pigment Cell & Melanoma Research; Sep2014, Vol. 27 Issue 5, p822-826, 6p |
| مصطلحات موضوعية: |
VISIBLE spectra, PHOTOBIOLOGY, MELANOGENESIS, HUMAN skin color, KERATINOCYTES, ULTRAVIOLET radiation |
| مستخلص: |
The visible light spectrum is wide, and it can be hypothesized that all the wavelengths between 400-700 nm do not induce the same photobiological effects on pigmentation. We assessed the potential pro-pigmenting effects of two single wavelengths located at both extremities of the visible spectrum: the blue/violet line (λ = 415 nm) and the red line (λ = 630 nm). We made colorimetric, clinical, and histological assessments with increasing doses of those lights on healthy volunteers. Then, we compared these irradiations to non-exposed and UVB-exposed skin. Colorimetric and clinical assessments showed a clear dose effect with the 415-nm irradiation, in both skin type III and IV subjects, whereas the 630 nm did not induce hyperpigmentation. When compared to UVB irradiation, the blue-violet light induced a significantly more pronounced hyperpigmentation that lasted up to 3 months. Histological examination showed a significant increase of keratinocyte necrosis and p53 with UVB, as compared to 415- and 630-nm exposures. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
