Functional Strain-Line Pattern in the Human Left Ventricle
| العنوان: | Functional Strain-Line Pattern in the Human Left Ventricle |
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| المؤلفون: | Jan Mangual, Partho P. Sengupta, Giuseppe Caracciolo, Alessio De Luca, Federico Domenichini, Amil M. Shah, Giovanni Tonti, Jagat Narula, Elisabeth Kraigher-Krainer, Scott D. Solomon, Gianni Pedrizzetti, Loira Toncelli, Giorgio Galanti |
| المساهمون: | Pedrizzetti, Gianni, Kraigher Krainer, E, De Luca, A, Caracciolo, G, Mangual, Jo, Shah, A, Toncelli, L, Domenichini, F, Tonti, G, Galanti, G, Sengupta, Pp, Narula, J, Solomon, S. |
| المصدر: | Physical Review Letters. 109 |
| بيانات النشر: | American Physical Society (APS), 2012. |
| سنة النشر: | 2012 |
| مصطلحات موضوعية: | Cardiac function curve, Physics, Beating heart, Cardiac cycle, Principal direction, Heart Ventricles, Models, Cardiovascular, General Physics and Astronomy, Heart, Strain (injury), Anatomy, medicine.disease, Ventricular Function, Left, cardiac mechanics, medicine.anatomical_structure, Ventricle, Line (geometry), medicine, Humans, Deformation (engineering), Magnetic Resonance Angiography |
| الوصف: | Analysis of deformations in terms of principal directions appears well suited for biological tissues that present an underlying anatomical structure of fiber arrangement. We applied this concept here to study deformation of the beating heart in vivo analyzing 30 subjects that underwent accurate three-dimensional echocardiographic recording of the left ventricle. Results show that strain develops predominantly along the principal direction with a much smaller transversal strain, indicating an underlying anisotropic, one-dimensional contractile activity. The strain-line pattern closely resembles the helical anatomical structure of the heart muscle. These findings demonstrate that cardiac contraction occurs along spatially variable paths and suggest a potential clinical significance of the principal strain concept for the assessment of mechanical cardiac function. The same concept can help in characterizing the relation between functional and anatomical properties of biological tissues, as well as fiber-reinforced engineered materials. |
| وصف الملف: | STAMPA |
| تدمد: | 1079-7114 0031-9007 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0201a8284cd821912ac6439b050d7353Test https://doi.org/10.1103/physrevlett.109.048103Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....0201a8284cd821912ac6439b050d7353 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 10797114 00319007 |
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