Influence of Geant4 parameters on dose distribution and computation time for carbon ion therapy simulation
| العنوان: | Influence of Geant4 parameters on dose distribution and computation time for carbon ion therapy simulation |
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| المؤلفون: | Philippe Lautesse, L. Grevillot, Thibault Frisson, David Sarrut, N. Zahra |
| المساهمون: | Institut de Physique Nucléaire de Lyon (IPNL), Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3), Centre Léon Bérard [Lyon], Centre de Recherche et d'Application en Traitement de l'Image et du Signal (CREATIS), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National des Sciences Appliquées de Lyon (INSA Lyon), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-École Supérieure Chimie Physique Électronique de Lyon-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Matière Nucléaire, Institut de Physique des 2 Infinis de Lyon (IP2I Lyon), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS), CCIN2P3 |
| المصدر: | Physica Medica Physica Medica, Elsevier, 2010, 26 (4), pp.202-8. ⟨10.1016/j.ejmp.2009.12.001⟩ |
| بيانات النشر: | Elsevier BV, 2010. |
| سنة النشر: | 2010 |
| مصطلحات موضوعية: | MESH: Radiation Dosage, Work (thermodynamics), Time Factors, Computation, Biophysics, General Physics and Astronomy, Linear energy transfer, MESH: Carbon, Bragg peak, Dose distribution, Radiation Dosage, Models, Biological, 030218 nuclear medicine & medical imaging, MESH: Software, 03 medical and health sciences, 0302 clinical medicine, Neoplasms, Humans, Dosimetry, MESH: Neoplasms, Radiology, Nuclear Medicine and imaging, MESH: Radiotherapy Dosage, Physics, MESH: Humans, MESH: Time Factors, Uncertainty, MESH: Models, Biological, Radiotherapy Dosage, General Medicine, Carbon, 030220 oncology & carcinogenesis, Carbon ion therapy, Particle, [SDV.IB]Life Sciences [q-bio]/Bioengineering, Atomic physics, Tomography, X-Ray Computed, MESH: Tomography, X-Ray Computed, Software, MESH: Uncertainty |
| الوصف: | International audience; The aim of this work was to study the influence of Geant4 parameters on dose distribution and computational time for simulations of carbon ion therapy. The study was done using Geant4 version 9.0. The dose distribution in water for incident monoenergetic carbon ion beams of 300 MeV/u were compared for different values of secondary particle production threshold and different step limits. Variations of depth dose of about 2 mm were observed in some cases, which induced a 30% variation of dose deposit in the Bragg peak region. Other tests were done using Geant4 version 9.2 to verify the results from this study. The two versions provided converging results and led to the same conclusions. |
| تدمد: | 1120-1797 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3175017ef3d6c0e7b9a3837eaba67ebbTest https://doi.org/10.1016/j.ejmp.2009.12.001Test |
| حقوق: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....3175017ef3d6c0e7b9a3837eaba67ebb |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 11201797 |
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