نتائج البحث

1

A gene variant near ATM affects the response to metformin and metformin plasma levels

المؤلفون: Ron H.N. van Schaik, Adriaan Kooy, Mattijs Out, Coen D.A. Stehouwer, Matthijs L. Becker, Philippe Lehert

المساهمون: Interne Geneeskunde, RS: CARIM - R3.01 - Vascular complications of diabetes and the metabolic syndrome, MUMC+: HVC Pieken Maastricht Studie (9), MUMC+: MA Interne Geneeskunde (3), Pharmacy, Clinical Chemistry

المصدر: Pharmacogenomics, 19(8), 715-726. FUTURE MEDICINE LTD
Pharmacogenomics, 19(8), 715-726. Future Medicine Ltd.

مصطلحات موضوعية: Male, 0301 basic medicine, PHARMACOKINETICS, endocrine system diseases, ATM protein, medicine.medical_treatment, SLC47A1 GENE, Ataxia Telangiectasia Mutated Proteins, Type 2 diabetes, OCT1, law.invention, 0302 clinical medicine, Randomized controlled trial, TOXIN EXTRUSION 1, law, Insulin, Medicine, Aged, 80 and over, GLYCEMIC RESPONSE, INSULIN-RESISTANCE, digestive, oral, and skin physiology, Organic Cation Transporter 1, drug, Middle Aged, Metformin, Molecular Medicine, Female, medicine.drug, Adult, medicine.medical_specialty, Genotype, Organic Cation Transport Proteins, TYPE-2 DIABETES-MELLITUS, 030209 endocrinology & metabolism, Polymorphism, Single Nucleotide, dose-response relationship, 03 medical and health sciences, Insulin resistance, Pharmacokinetics, Internal medicine, Post-hoc analysis, Genetics, Humans, Hypoglycemic Agents, human, ATAXIA-TELANGIECTASIA, CATION TRANSPORTER 1, POLYMORPHISMS, Aged, Pharmacology, business.industry, Type 2 Diabetes Mellitus, nutritional and metabolic diseases, medicine.disease, 030104 developmental biology, Endocrinology, Diabetes Mellitus, Type 2, business, metformin

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d45234f1904d5cec75c57e7d35f0aabTest
https://research.rug.nl/en/publications/a6849eb9-2c6b-47b0-9156-7b42dbd01519Test

2

Effects of genetic variability on rifampicin and isoniazid pharmacokinetics in South African patients with recurrent tuberculosis

المؤلفون: Maxwell Chirehwa, Katya Govender, Kogieleum Naidoo, Sinaye Ncgapu, Paolo Denti, Ravesh Singh, John W. Adamson, Nonhlanhla Yende-Zuma, Helen McIlleron, Nesri Padayatchi, Anushka Naidoo, Veron Ramsuran

المصدر: Pharmacogenomics. 20:225-240

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfef653446ab981495bcfe7cd449f518Test
https://doi.org/10.2217/pgs-2018-0166Test

3

Pharmacogenomics and pharmacokinetics of efavirenz 400 or 600 mg in 184 treatment-naive HIV-infected patients in China

المؤلفون: Jingna Xun, Li Liu, Renfang Zhang, Hongzhou Lu, Jun Chen, Qiong Huang, Rong Chen, Yinzhong Shen, Corky Steinhart, Zhiliang Hu

المصدر: Pharmacogenomics. 21(13)

مصطلحات موضوعية: Adult, Cyclopropanes, Male, China, Efavirenz, CYP2B6, Anti-HIV Agents, HIV Infections, Pharmacology, 030226 pharmacology & pharmacy, Polymorphism, Single Nucleotide, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Pharmacokinetics, immune system diseases, Genetics, medicine, Hiv infected patients, Humans, 030212 general & internal medicine, ATP Binding Cassette Transporter, Subfamily B, Member 1, Tenofovir, business.industry, virus diseases, Lamivudine, biochemical phenomena, metabolism, and nutrition, Benzoxazines, Regimen, Cytochrome P-450 CYP2B6, chemistry, Pharmacogenetics, Pharmacodynamics, Pharmacogenomics, Alkynes, Molecular Medicine, Reverse Transcriptase Inhibitors, Female, business, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45651285ef3522b3e137d2597c1e76a7Test
https://pubmed.ncbi.nlm.nih.gov/32838647Test

4

Identification of host variants associated with overall survival of esophageal cancer patients receiving platinum-based therapy

المؤلفون: Enrica Rumiato, Alberto Ruol, Daniela Saggioro, Sandro Malacrida, Vanna Chiarion Sileni, Alberto Amadori, Elisa Boldrin, Giorgio Battaglia

المصدر: Pharmacogenomics. 21(6)

مصطلحات موضوعية: 0301 basic medicine, Oncology, Adult, Male, medicine.medical_specialty, Esophageal Neoplasms, medicine.medical_treatment, Antineoplastic Agents, Germline, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, Genetics, medicine, Overall survival, Humans, PPAR delta, Stage (cooking), Neoadjuvant therapy, Aged, Pharmacology, Cisplatin, Aged, 80 and over, business.industry, Organic Cation Transporter 1, Genetic Variation, Esophageal cancer, Middle Aged, medicine.disease, Neoadjuvant Therapy, Survival Rate, 030104 developmental biology, 030220 oncology & carcinogenesis, Molecular Medicine, Female, business, Pharmacogenetics, Drug metabolism, medicine.drug, Follow-Up Studies

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f25ccbba47523f98519af6fb05511758Test
https://pubmed.ncbi.nlm.nih.gov/32285752Test

5

SLCO1A2, SLCO1B1 and SLCO2B1 polymorphisms influences chloroquine and primaquine treatment in Plasmodium vivax malaria

المؤلفون: Maristela G Cunha, Maria Deise de Oliveira Ohnishi, Vinicius A. Sortica, Ândrea Kc Ribeiro-dos-Santos, Juliana Dal-Ri Lindenau, Ana Maria Revorêdo da Silva Ventura, Luciano Sp Guimarães, Sidney Eb Santos, Mara H. Hutz

المصدر: Pharmacogenomics
Repositório Digital do Instituto Evandro Chagas (Patuá)
Instituto Evandro Chagas (IEC)
instacron:IEC

مصطلحات موضوعية: 0301 basic medicine, Male, Primaquine, Organic Anion Transporters, chloroquine and primaquine, Parasitemia, Pharmacology, Polimorfismo Gen?tico, 0302 clinical medicine, Chloroquine, Primaquina / administra??o & dosagem, Genotype, transporter genes, biology, Liver-Specific Organic Anion Transporter 1, Treatment Outcome, Molecular Medicine, Drug Therapy, Combination, Female, Testes Farmacogen?micos, Brazil, medicine.drug, Research Article, Adult, 030231 tropical medicine, malaria, ABCC4, 03 medical and health sciences, Antimalarials, Mal?ria, parasitic diseases, Genetics, medicine, Malaria, Vivax, Humans, Cloroquina / administra??o & dosagem, Polymorphism, Genetic, medicine.disease, 030104 developmental biology, Immunology, biology.protein, SLCO1B1, Plasmodium vivax, Malaria, Pharmacogenetics

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::485c426a8e13a3bd62a4a7e6c96aa156Test
http://europepmc.org/articles/PMC7099631Test

6

Role of vitamin D pathway gene polymorphisms on rifampicin plasma and intracellular pharmacokinetics

المؤلفون: Giovanni Di Perri, Giovanna Fatiguso, Andrea Calcagno, Antonio D'Avolio, Ilaria Motta, Jessica Cusato, Sarah Allegra, Lorena Baietto, Fabio Favata, Stefano Bonora

المصدر: Pharmacogenomics. 18:865-880

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cc7df0c55eed770e2051b61c62df170Test
https://doi.org/10.2217/pgs-2017-0176Test

7

Polymorphisms in SLCO1B1 and UGT1A1 are associated with sorafenib-induced toxicity

المؤلفون: Esther Oomen-de Hoop, Leni van Doorn, Anne Lenting, Ferry A.L.M. Eskens, Sander Bins, Ron H.N. van Schaik, Samira El Bouazzaoui, Ron H.J. Mathijssen

المساهمون: Medical Oncology, Clinical Chemistry

المصدر: Pharmacogenomics, 17(14), 1483-1490. Future Medicine Ltd.

مصطلحات موضوعية: Adult, Male, Niacinamide, 0301 basic medicine, Oncology, Sorafenib, medicine.medical_specialty, Genotype, Abcg2, Antineoplastic Agents, Pharmacology, Polymorphism, Single Nucleotide, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, Genetics, Humans, Medicine, Glucuronosyltransferase, Aged, Retrospective Studies, biology, Liver-Specific Organic Anion Transporter 1, business.industry, Phenylurea Compounds, Liver Neoplasms, Middle Aged, medicine.disease, Multidrug Resistance-Associated Protein 2, digestive system diseases, Diarrhea, 030104 developmental biology, Treatment interruption, 030220 oncology & carcinogenesis, Hepatocellular carcinoma, Toxicity, biology.protein, Molecular Medicine, Female, medicine.symptom, business, SLCO1B1, Pharmacogenetics, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c97956b7127fa39e9116d1ccee26e59Test
https://doi.org/10.2217/pgs-2016-0063Test

8

Genome-wide association study identifies CAMKID variants involved in blood pressure response to losartan: the SOPHIA study

المؤلفون: Lorenzo Malatino, Cristina Barlassina, Giuseppe Regolisti, Emanuela Bulla, Tracy Ann Williams, Franco Veglio, Alessandra Sturani, Martina Chittani, Erika Salvi, Daniele Cusi, Andrea Semplicini, Giovanni Fresu, Eric Boerwinkle, Patrizia Bulla, Timo P. Hiltunen, Giuseppe Argiolas, Francesca Frau, Paolo Manunta, Daniele Braga, Silvia Pitzoi, Paolo Mulatero, Giuseppe A. Scioli, Maria Francesca Ortu, Kimmo Kontula, Valeria Glorioso, Chiara Lanzani, Roberta Zaninello, Francesco Fallo, Daniela Antonella Piras, Ezio Degli Esposti, Benedetta Stancanelli, Angela Sciacqua, Ferruccio Galletti, Michele Bardini, Nicola Glorioso, Giovanbattista Desideri, Chiara Troffa, Dinesh Velayutham, Giampaolo Bernini, Francesco Perticone, Claudio Ferri, Stephen T. Turner

المساهمون: Frau, F, Zaninello, R, Salvi, E, Ortu, Mf, Braga, D, Velayutham, D, Argiolas, G, Fresu, G, Troffa, C, Bulla, E, Bulla, P, Pitzoi, S, Piras, Da, Glorioso, V, Chittani, M, Bernini, G, Bardini, M, Fallo, F, Malatino, L, Stancanelli, B, Regolisti, G, Ferri, C, Desideri, G, Scioli, Ga, Galletti, Ferruccio, Sciacqua, A, Perticone, F, Degli Esposti, E, Sturani, A, Semplicini, A, Veglio, F, Mulatero, P, Williams, Ta, Lanzani, C, Hiltunen, Tp, Kontula, K, Boerwinkle, E, Turner, St, Manunta, P, Barlassina, C, Cusi, D, Glorioso, N.

المصدر: Pharmacogenomics. 15:1643-1652

مصطلحات موضوعية: Male, Angiotensin receptor, losartan, Blood Pressure, Genome-wide association study, 030204 cardiovascular system & hematology, Pharmacology, Essential hypertension, genomic, chemistry.chemical_compound, 0302 clinical medicine, Hydrochlorothiazide, 0303 health sciences, angiotensin II receptor blockers, Aldosterone, genome-wide association analysi, Medicine (all), Single Nucleotide, Middle Aged, 3. Good health, angiotensin II receptor blocker, Losartan, Molecular Medicine, Female, Arterial hypertension, Genetic markers, medicine.drug, Adult, hypertension, Polymorphism, Single Nucleotide, 03 medical and health sciences, genomics, Genetics, medicine, Humans, Polymorphism, angiotennsin II receptor, pharmacogenomics, 030304 developmental biology, business.industry, medicine.disease, genome-wide association analysis, Angiotensin II Type 1 Receptor Blockers, Calcium-Calmodulin-Dependent Protein Kinase Type 1, Hypertension, Genome-Wide Association Study, Blood pressure, chemistry, Pharmacogenomics, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c494ceb4da81de88f873cadcca3ce4aTest
https://doi.org/10.2217/pgs.14.119Test

9

Differences in genetic variants in lopinavir disposition among HIV-infected Bantu Africans

المؤلفون: Pete Smith, Sandra Castel, Miguel Lacerda, Nyarai D Soko, Michelle Skelton, Lubbe Wiesner, Elizabeth Kampira, Collet Dandara, Bafokeng Mpeta, Keleabetswe L Mpye

المصدر: Pharmacogenomics. 17:679-690

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb1c0c11f1b39a5009073fc6c9ead931Test
https://doi.org/10.2217/pgs.16.14Test

10

Prolactin levels: sex differences in the effects of risperidone, 9-hydroxyrisperidone levels, CYP2D6 and ABCB1 variants

المؤلفون: Francisco J. Diaz, Jose de Leon, Georgios Schoretsanitis

المصدر: Pharmacogenomics. 19(10)

مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, ABCB1 gene, CYP2D6, 9-Hydroxyrisperidone, ATP Binding Cassette Transporter, Subfamily B, Genotype, Risperidone+9-Hydroxyrisperidone, Biology, 030226 pharmacology & pharmacy, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, Paliperidone Palmitate, Genetics, medicine, Humans, ATP Binding Cassette Transporter, Subfamily B, Member 1, Genetic Association Studies, Pharmacology, Sex Characteristics, Risperidone, Haplotype, Plasma prolactin, Middle Aged, Prolactin, 030227 psychiatry, Endocrinology, Cytochrome P-450 CYP2D6, Haplotypes, Molecular Medicine, Female, hormones, hormone substitutes, and hormone antagonists, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30e3e930a7a9900bfe996a9af000f953Test
https://pubmed.ncbi.nlm.nih.gov/29914302Test

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