دورية أكاديمية

Venoarterial Extracorporeal Membrane Oxygenation With or Without Advanced Intervention for Massive Pulmonary Embolism

التفاصيل البيبلوغرافية
العنوان: Venoarterial Extracorporeal Membrane Oxygenation With or Without Advanced Intervention for Massive Pulmonary Embolism
المؤلفون: Cardona, Stephanie, Downing, Jessica V, Witting, Michael D, Haase, Daniel J, Powell, Elizabeth K, Dahi, Siamak, Pasrija, Chetan, Tran, Quincy K
المصدر: Perfusion ; page 026765912311779 ; ISSN 0267-6591 1477-111X
بيانات النشر: SAGE Publications
سنة النشر: 2023
مصطلحات موضوعية: Advanced and Specialized Nursing, Cardiology and Cardiovascular Medicine, Safety Research, Radiology, Nuclear Medicine and imaging, General Medicine
الوصف: Introduction Massive pulmonary embolism (MPE) is a rare but highly fatal condition. Our study’s objective was to evaluate the association between advanced interventions and survival among patients with MPE treated with venoarterial extracorporeal membrane oxygenation (VA-ECMO). Methods This is a retrospective review of the Extracorporeal Life Support Organization (ELSO) registry data. We included adult patients with MPE who were treated with VA-ECMO during 2010–2020. Our Primary outcome was survival to hospital discharge; secondary outcomes were ECMO duration among survivors and rates of ECMO-related complications. Clinical variables were compared using the Pearson chi-square and Kruskal-Wallis H tests. Results We included 802 patients; 80 (10%) received SPE and 18 (2%) received CDT. Overall, 426 (53%) survived to discharge; survival was not significantly different among those treated with SPE or CDT on VA-ECMO (70%) versus VA-ECMO alone (52%) or SPE or CDT before VA-ECMO (52%). Multivariable regression found a trend towards increased survival among those treated with SPE or CDT while on ECMO (AOR 1.8, 95% CI 0.9–3.6), but no significant correlation. There was no association between advanced interventions and ECMO duration among survivors, or rates of ECMO-related complications. Conclusion Our study found no difference in survival in patients with MPE who received advanced interventions prior to ECMO, and a slight non-significant benefit in those who received advanced interventions while on ECMO.
نوع الوثيقة: article in journal/newspaper
اللغة: English
DOI: 10.1177/02676591231177909
الإتاحة: https://doi.org/10.1177/02676591231177909Test
حقوق: http://journals.sagepub.com/page/policies/text-and-data-mining-licenseTest
رقم الانضمام: edsbas.898449A8
قاعدة البيانات: BASE