دورية أكاديمية

Mortality and neurodevelopmental outcomes in very low birth weight infants with esophageal atresia.

التفاصيل البيبلوغرافية
العنوان: Mortality and neurodevelopmental outcomes in very low birth weight infants with esophageal atresia.
المؤلفون: Miyake, Hiromu, Nakano, Reiji, Yamamoto, Seiichiro, Isayama, Tetsuya, Sasaki, Hatoko
المصدر: Pediatric Surgery International; 11/17/2023, Vol. 39 Issue 1, p1-11, 11p
مصطلحات موضوعية: LOW birth weight, VERY low birth weight, ESOPHAGEAL atresia, BIRTH weight, NEURAL development
مصطلحات جغرافية: JAPAN
مستخلص: Purpose: Very low birth weight infants (VLBWIs) have been thought as risk of bad outcomes in the patients with esophageal atresia (EA). However, detailed outcomes of EA within VLBWIs were not fully understood. We aimed to reveal short- and long-term outcomes in VLBWIs with EA. Methods: Clinical data regarding VLBWIs with EA registered in Neonatal Research Network Japan, a multicenter research database in Japan, were collected. Patients with chromosomal abnormality were excluded. Short term outcome was survival discharge from NICU and long-term outcome was neurodevelopmental impairment (NDI) at 3 years. Results: A total of 103 patients were analyzed. the overall survival discharge rate from NICU was 68.0% (70/103). The risk of death was increased as the birth weight got reduced. The presence of associated anomaly increased the risk of death. Three-year neurodevelopmental information was available in 32.9% (23/70) of patients. Of the 23 included patients for 3-year follow-up, 34.8% had NDI. The risk of NDI was increased as the birth weight reduced. Conclusions: In VLBWIs with EA, survival discharge from NICU was still not high. More immature patients and patients with an associated anomaly had worse outcomes. Among patients who survived, NDI was confirmed in a certain number of patients. [ABSTRACT FROM AUTHOR]
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قاعدة البيانات: Complementary Index
الوصف
تدمد:01790358
DOI:10.1007/s00383-023-05579-8