التفاصيل البيبلوغرافية
| العنوان: |
GASTRIC ANGIODYSPLASIA IN A CHILD WITH BERNARD-SOULIER SYNDROME: Efficacy of Octreotide in Long-Term Management. |
| المؤلفون: |
Kaya, Zühre, Gürsel, Türkiz, Dalgic, Buket, Aslan, Deniz |
| المصدر: |
Pediatric Hematology & Oncology; Apr2005, Vol. 22 Issue 3, p223-227, 5p |
| مصطلحات موضوعية: |
BLOOD-vessel abnormalities, OCTREOTIDE acetate, GASTROINTESTINAL diseases, JUVENILE diseases, HEMORRHAGE |
| مستخلص: |
Gastrointestinal angiodysplasia in association with Bernard-Soulier syndrome has been previously described in adults. The authors report on a 14-year-old boy presenting with massive upper gastrointestinal bleeding due to a large gastric angiodysplasia, in whom medical history and laboratory investigations were consistent with Bernard-Soulier syndrome. The vascular lesion was so widespread that surgical or endoscopic therapy was not considered. Therefore, treatment with octreotide, a somatostatin analog, was commenced, following a short course of tranexamic acid and proton pump inhibitor. During the 16-month follow-up with octreotide therapy, no occult or gross bleeding occurred. This case illustrates the utility of using octreotide for the long-term treatment of children with bleeding disorders and angiodysplasia. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
