دورية أكاديمية

Pediatric Diabetes Consortium Type 1 Diabetes New Onset (NeOn) Study: factors associated with HbA1c levels one year after diagnosis.

التفاصيل البيبلوغرافية
العنوان: Pediatric Diabetes Consortium Type 1 Diabetes New Onset (NeOn) Study: factors associated with HbA1c levels one year after diagnosis.
المؤلفون: Redondo, Maria J, Connor, Crystal G, Ruedy, Katrina J, Beck, Roy W, Kollman, Craig, Wood, Jamie R, Buckingham, Bruce, Klingensmith, Georgeanna J, Silverstein, Janet, Tamborlane, William V
المصدر: Pediatric Diabetes; Jun2014, Vol. 15 Issue 4, p294-302, 9p
مصطلحات موضوعية: DIABETIC acidosis, TREATMENT of diabetes, TYPE 1 diabetes, AUTOANTIBODIES, BICARBONATE ions, ETHNIC groups, GLUTAMIC acid, GLYCOSYLATED hemoglobin, INCOME, INSULIN, MEDICAL societies, PEDIATRICS, RACE, DATA analysis, SOCIOECONOMIC factors, BODY mass index, ACQUISITION of data, DISEASE duration, DIAGNOSIS
مستخلص: Objective To identify determinants of hemoglobin A1c ( HbA1c) levels 1 yr after the diagnosis of type 1 diabetes ( T1D) in participants in the Pediatric Diabetes Consortium ( PDC) T1D New Onset ( NeOn) Study. Research design and methods: Diabetes-specific as well as socioeconomic factors during the first year following diagnosis were analyzed in 857 participants (mean age 9.1 yrs, 51% female, 66% non-Hispanic White) not participating in an intervention study who had an HbA1c value at 12 months. Result Mean ± SD HbA1c at 1 yr was 62 ± 16 mmol/mol (7.8% ± 1.5). In univariate and multivariate analyses, clinical center, non-Hispanic White race, private health insurance, living with both parents, higher frequency of self-monitoring of blood glucose ( SMBG), and lower insulin requirements were associated with lower HbA1c concentrations at 1 yr (p < 0.01). No association was found with gender, age, Tanner stage, body mass index ( BMI), diabetic ketoacidosis ( DKA) at onset, number of positive autoantibodies or HbA1c at onset, or number of visits to diabetes physician during the first year. Conclusions White race, higher socioeconomic status, two-parent household, more frequent SMBG, and low insulin requirements are associated with lower HbA1c concentration 1 yr after the onset of T1D in children. [ABSTRACT FROM AUTHOR]
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قاعدة البيانات: Complementary Index
الوصف
تدمد:1399543X
DOI:10.1111/pedi.12061