دورية
The effect of praziquantel treatment on glutathione concentration in Schistosoma mansoni (Praziquantel and glutathione in Schistosoma mansoni )
| العنوان: | The effect of praziquantel treatment on glutathione concentration in |
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| المؤلفون: | *, F. RIBEIRO, , *, P. M. Z. COELHO, , *, L. Q. VIEIRA, §, *, D. G. WATSON, **, KUSEL, J. R. |
| المصدر: | Parasitology; March 1998, Vol. 116 Issue: 3 p229-236, 8p |
| مستخلص: | A fluorescent dye monochlorobimane (MCB) that binds glutathione (GSH) was used as a tool for measuring the concentration of GSH in skin and mechanically-transformed schistosomula. The specificity of MCB binding to GSH was confirmed by thin layer chromatography (TLC) and high performance liquid chromatography (HPLC). The MCB binding to GSH is an energy-dependent process since no labelling could be seen at low temperature. When 24-h-old schistosomula were depleted of GSH by buthionine sulfoximine (a specific inhibitor of GSH synthesis) for 18 h, a significant decrease ( |
| قاعدة البيانات: | Supplemental Index |
| تدمد: | 00311820 14698161 |
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