Dissection of the cecal microbial community in chickens after Eimeria tenella infection
| العنوان: | Dissection of the cecal microbial community in chickens after Eimeria tenella infection |
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| المؤلفون: | Chun-Wei Shi, Jian-Zhong Wang, Hong-Liang Chen, Wen-Tao Yang, Yanlong Jiang, Quan Zhao, Guang-Xun Zhao, Liping Ye, Xin-Yu Zhao, Gui-Lian Yang, Chun-Feng Wang, Hai-Bin Huang, Hao-Rui Li |
| المصدر: | Parasites & Vectors Parasites & Vectors, Vol 13, Iss 1, Pp 1-15 (2020) |
| بيانات النشر: | Springer Science and Business Media LLC, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | 0301 basic medicine, 030106 microbiology, Drug resistance, medicine.disease_cause, digestive system, Eimeria, lcsh:Infectious and parasitic diseases, Microbiology, 03 medical and health sciences, Cecum, Coccidia, RNA, Ribosomal, 16S, Lactobacillus, Chicken coccidiosis, parasitic diseases, medicine, Animals, lcsh:RC109-216, 16S rRNA, Poultry Diseases, Bacteria, biology, Coccidiosis, Research, Pathogenic bacteria, Alternative therapeutics, medicine.disease, biology.organism_classification, Gastrointestinal Microbiome, 030104 developmental biology, Infectious Diseases, medicine.anatomical_structure, Cecal microbiota, Parasitology, Metagenomics, Chickens, Eimeria tenella, Ruminococcaceae |
| الوصف: | BackgroundEimeriaspp. are responsible for chicken coccidiosis which is the most important enteric protozoan disease resulting in tremendous economic losses in the poultry industry. Understanding the interaction between the avian cecal microbiota and coccidia is of interest in the development of alternative treatments that do not rely on chemotherapeutics and do not lead to drug resistance.MethodsWe utilized16SrRNA gene sequencing to detect the dynamics of the cecal microbial community in AA broilers challenged withEimeria tenella. Histopathological analysis of the cecum was also conducted.ResultsWe found that microbial shifts occur during the infection.Lactobacillus,Faecalibacterium,RuminococcaceaeUCG-013,RomboutsiaandShuttleworthiadecreased in abundance. However, the opportunistic pathogensEnterococcusandStreptococcusincreased in abundance over time in response to the infection.ConclusionsEimeria tenelladisrupts the integrity of the cecal microbiota and could promote the establishment and growth of potentially pathogenic bacteria. Defining bacterial populations affected by coccidial infection might help identify bacterial markers for intestinal disease as well as populations or species that could be beneficial in maintaining and restoring gut homeostasis during and after infection withE. tenella. |
| تدمد: | 1756-3305 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::522ec628b18ae4c784ed3ef8e6d50f9bTest https://doi.org/10.1186/s13071-020-3897-6Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....522ec628b18ae4c784ed3ef8e6d50f9b |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 17563305 |
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