Prognostic Implications of the Immune Tumor Microenvironment in Patients With Pancreatic and Gastrointestinal Neuroendocrine Tumors

التفاصيل البيبلوغرافية
العنوان: Prognostic Implications of the Immune Tumor Microenvironment in Patients With Pancreatic and Gastrointestinal Neuroendocrine Tumors
المؤلفون: Haiying Xu, Anil Kotte, Marina Baretti, Robert A. Anders, Feriyl Bhaijee, Marianna Zahurak, Timothy M. Pawlik, Elizabeth L. Engle, Ana De Jesus-Acosta, Qingfeng Zhu
المصدر: Pancreas. 50:719-726
بيانات النشر: Ovid Technologies (Wolters Kluwer Health), 2021.
سنة النشر: 2021
مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Time Factors, Adolescent, CD3 Complex, T-Lymphocytes, Endocrinology, Diabetes and Metabolism, Programmed Cell Death 1 Receptor, Neuroendocrine tumors, Gastroenterology, B7-H1 Antigen, Young Adult, 03 medical and health sciences, Lymphocytes, Tumor-Infiltrating, 0302 clinical medicine, Endocrinology, Immune system, Internal medicine, PD-L1, Biomarkers, Tumor, Tumor Microenvironment, Internal Medicine, medicine, Humans, Aged, Gastrointestinal Neoplasms, Retrospective Studies, Tumor microenvironment, Hepatology, biology, Tumor-infiltrating lymphocytes, business.industry, Odds ratio, Middle Aged, medicine.disease, Progression-Free Survival, Pancreatic Neoplasms, Neuroendocrine Tumors, medicine.anatomical_structure, 030220 oncology & carcinogenesis, biology.protein, Female, 030211 gastroenterology & hepatology, Pancreas, business, CD8
الوصف: OBJECTIVES The aim of this study was to characterize the tumor microenvironment of patients with gastroenteropancreatic neuroendocrine tumors relative to progression-free survival (PFS). METHODS Immune profiling for CD3, CD8, programmed death-1/programmed death-ligand 1, and indoleamine 2,3-dioxygenase expression in 2 cohorts of gastroenteropancreatic neuroendocrine tumors: patients with short PFS (
تدمد: 1536-4828
0885-3177
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8429160a0cbd5f891c86624a537e751Test
https://doi.org/10.1097/mpa.0000000000001831Test
رقم الانضمام: edsair.doi.dedup.....c8429160a0cbd5f891c86624a537e751
قاعدة البيانات: OpenAIRE