التفاصيل البيبلوغرافية
| العنوان: |
Flare-up of hand osteoarthritis caused by zoledronic acid infusion. |
| المؤلفون: |
de Castro, G. R. Werner1,2 castrogrwc@gmail.com, Neves, F. S.1,2, de Magalhães Souza Fialho, S. C.2, Pereira, I. A.2, Ribeiro, G.2, Zimmermann, A. F.1,2 |
| المصدر: |
Osteoporosis International. Sep2010, Vol. 21 Issue 9, p1617-1619. 3p. 1 Color Photograph. |
| مصطلحات موضوعية: |
*CASE studies, *OSTEOARTHRITIS, *OSTEOPOROSIS, *INTRAVENOUS therapy, *DIPHOSPHONATES, *JOINTS (Anatomy), *CYTOKINES, *T cells, *BONE resorption inhibitors, *INFLAMMATION, *INFUSION therapy, *X-ray densitometry in medicine, *DISEASE exacerbation |
| مستخلص: |
Zoledronic acid is effective for osteoporosis at a single annual intravenous dose. It usually causes few adverse effects; the most common are related to acute phase reactions. We reported the case of a 64-year-old woman who presented flare-up of hand osteoarthritis after zoledronic acid infusions. Despite the fact that arthralgia is a common side effect of intravenous bisphosphonates, development of inflammatory signs in osteoarthritic joints is a rare event. We hypothesized that this side effect is caused by a release of cytokines secondary to activation of gamma-delta T lymphocytes. [ABSTRACT FROM AUTHOR] |
| قاعدة البيانات: |
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